Alliance for Pandemic Preparedness

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Tag: transmission


February 23, 2021

Reopening Schools in the Context of Increasing COVID-19 Community Transmission: The French Experience

Children and adolescents in France had lower risk of a positive SARS-CoV-2 PCR test and lower incidence of infection compared to adults during the first 2 months of the 2020-2021 school year (August to October 2020), though risk among older adolescents was close to that of adults. Schools re-opened with infection control measures in place,…


February 22, 2021

Inflight Transmission of COVID-19 Based on Experimental Aerosol Dispersion Data

A study simulating aerosol dispersion in a B77-200 aircraft to estimate SARS-CoV-2 infection probability calculated that the MID-AFT (economy class) portion of the cabin exhibited the highest infection probability, with the average individual infection probability (without masks) for a 2-hour flight in this section varying from 0.1% for a ‘Mild Scenario’ to 2.5% for a…


The Rise of SARS-CoV-2 Variant B.1.1.7 in Israel Intensifies the Role of Surveillance and Vaccination in Elderly

[Pre-print, not peer-reviewed] An analysis of over 300,000 RT-PCR samples collected in Israel between December 6th, 2020 and February 10th, 2021 in the general community and nursing homes found that the B.1.1.7 variant outcompeted the wildtype SARS-CoV-2 strain, representing 90% of positive tests. The variant was 45% more transmissible than wildtype. In addition, the transmission…


Reported COVID-19 Incidence in Wisconsin High School Athletes During Fall 2020

[Pre-print, not peer-reviewed] A study of COVID-19 in high school athletes in Wisconsin in September 2020 showed that 207 schools that reinitiated sports reported 270 COVID-19 cases among 30,074 players, for case and incidence rates of 809 cases per 100,000 players and 32.6 cases per 100,000 player-days, respectively. 115 (55%) cases were attributed to household…


Disparate Patterns of Movements and Visits to Points of Interest Located in Urban Hotspots across US Metropolitan Cities during COVID-19

A study examining the effect of social distancing on changes in visits to urban hotspot points of interest (POIs) in US cities from January to May 2020 found that one group of cities, including San Francisco, Seattle, and Chicago, there was a substantial decrease in hotspot POI visitors, while in another group, including Austin, Houston…


Clusters of SARS-CoV-2 Infection Among Elementary School Educators and Students in One School District — Georgia, December 2020–January 2021

An investigation of SARS-CoV-2 transmission in a school district in Georgia between December 1, 2020–January 22, 2021 identified nine clusters of COVID-19 cases involving 13 educators and 32 students at six of eight elementary schools. Two clusters involved probable educator-to-educator transmission that was followed by educator-to-student transmission in classrooms, resulting in approximately one half (15…


February 18, 2021

Epidemiological Dynamics of the Incidence of COVID-19 in Children and the Relationship with the Opening of Schools in Catalonia (Spain)

[Pre-print, not peer reviewed] Incidence of COVID-19 among children aged <18 years in Catalonia, Spain during the first 20 weeks of the 2020-2021 school year remained significantly lower than in the general population, except during late January 2021.  Test positivity was also lower among children than the general population, except in January 2021, when active…


February 17, 2021

Characteristics of SARS-CoV-2 Transmission among Meat Processing Workers in Nebraska, USA, and Effectiveness of Risk Mitigation Measures

There was a 19% COVID-19 attack rate (n=5,002 cases) among Nebraska meat processing workers during April 1–July 31, 2020. After implementing universal masking and physical barrier interventions, 8 of 13 facilities showed a statistically significant reduction in COVID-19 incidence in less than 10 days. While 67% of cases occurred among workers who identified as Hispanic…


February 11, 2021

Symptoms and Laboratory Manifestations of Mild COVID-19 in a Repatriated Cruise Ship Cohort

Among 49 passengers traveling from Uruguay to Australia on a cruise ship with high COVID-19 incidence in April 2020, 42% were asymptomatic and only 15% of symptomatic cases reported fever. Serial respiratory and rectal swabs were positive for 10% and 5% of participants, respectively, after a median of 3 weeks post-symptom onset. The authors suggest…


Emergence of a Novel SARS-CoV-2 Variant in Southern California

A novel variant of SARS-CoV-2 called “CAL.20C” was identified in Southern California and emerged contemporaneously with a local surge in cases. The authors define the variant on the basis of three mutations in the S-protein (S13I; W152C; and L452R) which differentiate the subclade from the 20C clade currently predominant in North America. The functional effect…



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