Result for
Tag: transmission
March 15, 2021
Household SARS-CoV-2 Transmission and Children: A Network Prospective Study
A study of SARS-CoV-2 household transmission in Spain found that while viral transmission was common among household members (62.3%), among the 1,040 children under age 16 included in the study, more than 70% (756) of cases were acquired from an adult, whereas only 7.7% (80) were index cases. Almost half (47.2%) were asymptomatic, 10.8% had…
Transmission of SARS-CoV-2 Infection among Children in Summer Schools Applying Stringent Control Measures in Barcelona, Spain
A study of SARS-CoV-2 transmission among children and staff in summer schools in Spain during July 2020 found that the transmission rate under strict prevention measures was lower in school-like facilities than the general population. The authors compared transmission rates using a normalized effective reproduction number that accounted for the time spent in each setting….
March 12, 2021
Impact of the COVID-19 Vaccine on Asymptomatic Infection Among Patients Undergoing Pre-Procedural COVID-19 Molecular Screening
The risk of asymptomatic SARS-CoV-2 infection was significantly lower among patients who had received at least 1 dose of an mRNA COVID-19 vaccine compared to unvaccinated patients, based on a retrospective cohort study of asymptomatic adult patients (n=39,156) across multiple US states undergoing a pre-procedural SARS-CoV-2 molecular screening test. SARS-CoV-2 was detected in 3% of…
March 11, 2021
COVID-19 Infections among Students and Staff in New York City Public Schools
Testing of asymptomatic students and staff in New York public schools determined that the incidence of COVID-19 was lower among the school population (341.1 cases per 100,000) compared to the citywide population (528.9 cases per 100,000). Of 234,132 asymptomatic persons tested for SARS-CoV-2 infection in New York City public schools during October to December 2020,…
March 10, 2021
Transmission Infectivity and Antibody Neutralization of an Emerging SARS-CoV-2 Variant in California Carrying a L452R Spike Protein Mutation
[Pre-print, not peer-reviewed] Whole genome sequencing of 2,172 remnant nasal/nasopharyngeal swab samples from 44 counties in California identified a novel SARS-CoV-2 variant characterized by three mutations in the spike protein named B.1.427/B.1.429 or 20C/L452R. This variant emerged around May 2020, and by January 29, 2021 represented >50% of sequenced cases, exhibiting an estimated 19-24% increase…
March 8, 2021
SARS-CoV-2 Transmission in Intercollegiate Athletics Not Fully Mitigated with Daily Antigen Testing
[Pre-print, not peer-reviewed] Two SARS-CoV-2 outbreaks occurred among US university athletic programs during the fall 2020 despite mandatory directly observed daily antigen testing, suggesting that antigen testing alone may not be sufficient to prevent outbreaks in congregate settings. In the first outbreak, 32 confirmed cases occurred within an athletics program after the index patient attended…
March 5, 2021
Just 2% of SARS-CoV-2-Positive Individuals Carry 90% of the Virus Circulating in Communities
[Pre-print, not peer-reviewed] An analysis of saliva specimens collected through a campus-wide surveillance program for SARS-CoV-2 among students at the University of Colorado, Boulder during the Fall academic semester of 2020 found that 2% (1,405 of 72,500 specimens tested) of the samples were positive for SARS-CoV-2. All of the positive students self-reported no symptoms on…
March 3, 2021
Persistent SARS-CoV-2 RNA Shedding without Evidence of Infectiousness: A Cohort Study of Individuals with COVID-19
A study of SARS-CoV-2 viral shedding showed that while most (97%) of people with mild to moderate COVID-19 continue to shed viral RNA for more than 10 days after symptom onset, virus could not be recovered by cell culture in any of the 35 individuals sampled more than 10 days after symptom onset. The authors…
Estimation of Secondary Household Attack Rates for Emergent SARS-CoV-2 Variants Detected by Genomic Surveillance at a Community-Based Testing Site in San Francisco
[Pre-print, not peer-reviewed] Some SARS-CoV-2 variants circulating in San Francisco with increasing prevalence may spread more efficiently to household contacts when compared to prior variants. Using SARS-CoV-2 genomic sequencing and epidemiological data collected from a walk-up rapid testing site in San Francisco, household contacts exposed to individuals infected with certain variants (including those with mutations…
March 2, 2021
Household COVID-19 Risk and in-Person Schooling
[Pre-print, not peer-reviewed] School-based mitigation measures reduced the odds of reporting COVID-19 like illness (CLI) and/or a positive SARS-CoV-2 PCR test result among household members living with a child attending in-person learning, according to an online survey of over 2 million US respondents conducted between November 2020 to January 2021. While the risk of reporting…
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