Result for
Tag: vaccinations
June 10, 2021
A Model and Predictions for COVID-19 Considering Population Behavior and Vaccination
A SARS-CoV-2 transmission model incorporating social behavioral changes in response to infection rates and vaccination rates suggests that a large increase in the sense of safety and a lowering of precautions due to vaccination to pre-pandemic levels could result in a surge of infections. However, the model predicted that new infections rates could approach zero…
Association of COVID-19 Vaccination Prioritization and Hospitalization among Older Washingtonians
Prioritization of individuals aged ≥65 years in Washington State for COVID-19 vaccination in January 2021 resulted in an estimated 434 fewer hospitalizations and 122 fewer deaths through March 2021 according to an analysis that compared actual age-specific COVID-19 hospitalization and fatality rates with a synthetic control group generated from a model based on age-specific COVID-19…
May 18, 2021
Surveillance of COVID-19 Vaccination in US Nursing Homes December 2020-April 2021
[Pre-print, not peer-reviewed] Data on vaccination coverage among nursing home residents and staff reported by pharmacies participating in the temporary federal Pharmacy Partnership for Long-Term Care Program correlated well with data reported by nursing homes to the new COVID-19 vaccination modules of the CDC’s National Healthcare Safety Network (NHSN) throughout January 2021 (r=0.89-0.97 for residents…
April 29, 2021
Antibody Response to Coronavirus Disease 2019 (COVID-19) Messenger RNA Vaccination in Pregnant Women and Transplacental Passage Into Cord Blood
Among 122 pregnant women who delivered on or after 35 weeks gestation and received a COVID-19 mRNA vaccine by the time of delivery (n= 55 first dose, n=67 both doses), anti-SARS-CoV-2 IgG antibodies were detected in maternal blood as early as 5 days and in cord blood as early as 16 days after the first…
April 13, 2021
Age-Dependence of Healthcare Interventions for COVID-19 in Ontario, Canada
More than half of people who died of COVID-19 in Ontario, Canada (3,475 of 6,728) had no record of hospitalization for treatment related to COVID-19 (up to February 2021). Hospitalizations were relatively uniform between ages 60-90 years, while deaths were more concentrated in ages 80 and above. Using a generalized linear model, the estimated probability…
April 1, 2021
COVID-19 Vaccine Impact on Rates of SARS-CoV-2 Cases and Post Vaccination Strain Sequences among Healthcare Workers at an Urban Academic Medical Center a Prospective Cohort Study
[Pre-print, not peer-reviewed] Among a cohort of healthcare workers (HCW) from Boston Medical Center who received the first dose of either the Pfizer-BioNTech or Moderna vaccines, the SARS-CoV-2 infection rate was 27% and 82% lower 1-14 days and >14 days after receiving the first dose, respectively, compared to surrounding community infection rates. SARS-CoV-2 infections occurred…
March 5, 2021
Association between Influenza Vaccination and Hospitalisation or All-Cause Mortality in People with COVID-19: A Retrospective Cohort Study
A retrospective cohort study using routinely collected health records from patients with COVID-19 (n= 6,921) in South West England between January and July 2020 found that receiving the influenza vaccination sometime between January 1, 2019 and COVID-19 diagnosis was associated with a 15% reduced odds of all-cause mortality or hospitalization (aOR=0.85), and a 24% reduced…
February 26, 2021
The Public Health Impact of Delaying a Second Dose of the BNT162b2 or MRNA-1273 COVID-19 Vaccine
[Pre-print, not peer-reviewed] An agent-based model estimated the impact of a strategy of delaying a second COVID-19 vaccine dose on cumulative mortality and found that a delayed second dose approach could result in reduced cumulative mortality under certain conditions, particularly in people under 65 years of age. The model was constructed using a simulated population…
Obesity May Hamper SARS-CoV-2 Vaccine Immunogenicity
[pre-print; not peer-reviewed] Antibody titers two weeks after receiving a second dose of the Pfizer-BioNTech vaccine were lower in obese healthcare workers (BMI >30), after adjusting for age. 99.5% of the 248 participants developed a humoral immune response after vaccination, and antibody titers were higher in younger people and in women. The authors note that…
February 24, 2021
Healthcare Personnel Knowledge Motivations Concerns and Intentions Regarding COVID-19 Vaccines a Cross-Sectional Survey
[Pre-print, not peer-reviewed] A cross-sectional survey of healthcare professionals (HCP) (n=2,448) from three Northern California medical centers conducted from November 16-December 8, 2020 indicated that overall enthusiasm for the COVID-19 vaccine was strong, and more HCP (69%) said they would definitely/likely receive vaccine if it were formally FDA-approved versus if it were approved via emergency…