Result for
Topic: Clinical Characteristics and Health Care Setting
November 30, 2020
Are Psychiatric Disorders Risk Factors for COVID-19 Susceptibility and Severity: A Two-Sample Bidirectional Univariable and Multivariable Mendelian Randomization Study
[Pre-print, not peer-reviewed] An analysis of potential bidirectional relationships between neuropsychiatric disorders and COVID-19 showed that genetic liability to bipolar disorder slightly increased COVID-19 susceptibility and severity, and there was no consistent evidence of COVID-19 influencing risk of developing psychiatric disorders. A combination of bipolar disorder and schizophrenia was associated with greater risk of contracting…
Community Coronavirus Disease 2019 Activity Level and Nursing Home Staff Testing for Active Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Indiana
A study assessing the potential utility of COVID-19 community SARS-CoV-2 test positivity levels or incidence to inform testing strategies of nursing home staff in Indiana did not find a meaningful threshold to predict homes with SARS-CoV-2-positive staff. Using county-level metrics of cases per 10,000 population or positivity rates to predict detection of any infected staff…
Delayed Healthcare Seeking and Prolonged Illness in Healthcare Workers during the COVID-19 Pandemic: A Single-Centre Observational Study
A cross-sectional study at a London hospital found that some healthcare workers with severe symptoms of COVID-19 delayed seeking medical attention. Of 236 healthcare workers who reported symptoms consistent with COVID-19, the most common symptoms were cough (76%), fever (59%), breathlessness (36%), and loss of smell (42%). Five of nine respondents experiencing severe breathlessness and…
November 25, 2020
Higher Viral Loads in Asymptomatic COVID-19 Patients Might Be the Invisible Part of the Iceberg
By comparing viral loads of asymptomatic and symptomatic laboratory-confirmed COVID-19 patients in samples obtained on admission to a hospital, researchers found that asymptomatic patients had higher SARSCoV-2 viral loads than symptomatic patients. Viral loads decreased with increasing disease severity. Viral loads of patients with at least one comorbidity (i.e., hypertension, diabetes, malignancy, chronic pulmonary disease)…
Implementation of Hospital Practices Supportive of Breastfeeding in the Context of COVID-19 — United States, July 15–August 20, 2020
During summer 2020, 18% of hospitals reported that in-person lactation support for new mothers had decreased. An analysis of data from 1,344 US hospitals indicated that hospitals were attempting to balance evidence-based practices to support breastfeeding with SARS-CoV-2 infection control measures. For mothers with suspected or confirmed COVID-19, 14% of hospitals discouraged and 7% prohibited…
November 24, 2020
Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and Meta-Analysis
A systematic review and meta-analysis (n=47 studies) found that compared to healthy children, children with comorbidities had a 1.8-fold increase in risk for sever COVID-19. Underlying conditions and obesity were also associated with higher risk of COVID-19-associated mortality. Tsankov et al. (Nov 20, 2020). Severe COVID-19 Infection and Pediatric Comorbidities: A Systematic Review and…
Surviving COVID-19 After Hospital Discharge: Symptom, Functional, and Adverse Outcomes of Home Health Recipients
A retrospective observational cohort study of COVID-19 survivors admitted to home health care (HHC) post-hospitalization in New York City (n=1,409) found that after an average of 32 days in HHC, most patients experienced significant improvements in symptoms and function. 94% were discharged from HHC. Risk of rehospitalization or death (137 rehospitalizations, 11 deaths) was associated…
Assessment of 135 794 Pediatric Patients Tested for Severe Acute Respiratory Syndrome Coronavirus 2 Across the United States
In a cohort of US pediatric patients (n=135,794; mean age=8.8), 5,374 (4%) tested positive for SARS-CoV-2, of whom 359 (7%) were hospitalized and 8 died (case fatality proportion = 0.2%). Despite lower rates of testing compared with White patients, participants of Black, Hispanic, and Asian race/ethnicity were more likely to have positive test results. Older…
November 23, 2020
Comprehensive Health Assessment Three Months after Recovery from Acute COVID-19
A study following patients (n = 124) for 3 months after they were discharged from the hospital following recovery from COVID-19 in the Netherlands reported that a substantial proportion reported severe problems in several health domains including functional impairment (64%), fatigue (69%) and quality of life (72%) after recovery from acute COVID-19. van den Borst…
Epidemiological and Clinical Characteristics of COVID-19 in Children: A Systematic Review and Meta-Analysis
A meta-analysis (n = 96 studies) of the clinical characteristics of SARS-CoV-2 in children (mean age 6.5 years) reported that 90% had household contact with an individual with SARS-CoV-2, 23% were asymptomatic, 27% had at least one comorbidity, and 29% had a co-infection, such as with mycoplasma or influenza. The pooled incubation period was 9.6…
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