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Topic: Clinical Characteristics and Health Care Setting
October 9, 2020
Follow-up of Adults with Non-Critical COVID-19 Two Months after Symptoms’ Onset
Two-thirds of adults with non-critical COVID-19 experienced persisting symptoms up to 2 months after initial onset, with symptoms including loss of taste or smell, difficulty breathing, and fatigue. In an observational study of 150 patients with mild or moderate COVID-19, persisting symptoms at 60 days were significantly more common among those age 40 to 60…
Characteristics of Hospitalized Children With SARS-CoV-2 in the New York City Metropolitan Area
Children with comorbidities who were hospitalized with SARS-CoV-2 were at increased risk for critical care admission and/or need for respiratory support, based on results from a multicenter, retrospective cohort study at four hospitals in the New York City metropolitan area. Obesity was the most commonly observed risk factor for critical care (63% vs. 28%), while…
October 8, 2020
Extended Use or Re-Use of Single-Use Surgical Masks and Filtering Facepiece Respirators during COVID-19: A Rapid Systematic Review
A rapid systematic review found limited evidence of protective efficacy when surgical masks and N95 respirators are either reused or had extended use in frontline healthcare settings. Despite limited evidence, the review highlighted vaporized hydrogen peroxide and ultraviolet irradiation as the most promising reprocessing methods. The level of detail and consistency varied across the 6…
Risk of COVID-19 from Hospital Admission during the Pandemic
Nalleballe et al. report on 101,533 patients hospitalized for a non-COVID-19 related illness included in a global clinical research database representing 45 health care organizations. Only 44 (0.043%) tested positive for SARS-CoV-2 within 14 days of discharge between January and June 2020. These results suggest that risk of contracting SARS-CoV-2 during a hospital admission is…
October 7, 2020
State Actions and Shortages of Personal Protective Equipment and Staff in U.S. Nursing Homes
In June-July 2020, nearly half (47%) of nursing home facilities in the US reported a shortage of personal protective equipment (PPE) and/or staff needed to protect residents and staff from COVID‐19. Thirty percent of facilities reported at least one week of staffing shortage, and 28% reported at least one week of PPE shortage. These data were…
October 6, 2020
A Prospective Study of Neurologic Disorders in Hospitalized COVID-19 Patients in New York City
A prospective multi-center observational study of hospitalized COVID-19 patients in New York City (n=4,491) found that 14% of patients developed a new neurological disorder at a median of 2 days after COVID-19 symptom onset, which was also associated with increased adjusted risk of in-hospital mortality and decreased likelihood of hospital discharge. The most common diagnoses…
Association of Smoking Status with Outcomes in Hospitalised Patients with COVID-19
Analysis of a large retrospective study (n=1,137) found that among adults hospitalized with COVID-19, smokers were more likely to develop critical illness that required mechanical ventilation (47% vs 37%, p=0.005). In univariate analysis, current smokers had a 1.6-fold higher risk of death compared with never smokers (95% CI: 1.2-2.1). In adjusting for confounders, female sex,…
October 5, 2020
Patient-Reported Outcome Measures after COVID-19: A Prospective Cohort Study
Among 78 patients who were hospitalized with COVID-19 from March to June 2020 in Vancouver, Canada, 76% reported having at least one lingering health effect 3 months after symptom onset and 56% reported at least 2 health effects. The most frequently reported complaints were lower quality of life (51%) and shortness of breath (50%). Wong…
An Analysis of Changes in Emergency Department Visits After a State Declaration During the Time of COVID-19
An urban level 1 trauma center in Minnesota experienced a 35% decline in emergency department visits in 28 days following the state emergency declaration of COVID-19 on March 13, 2020, as compared with a similar period in 2019. Disproportionate declines were seen in visits by pediatric and older patients, women, and Medicare recipients, as well…
Seroprevalence of SARS-COV-2 Antibodies in Scottish Healthcare Workers
[Preprint, not peer-reviewed] Health and social care workers in a National Health Service facility in the UK (n=2,062) were three times more likely to test positive for anti-SARS-CoV-2 antibodies, compared to a group of controls (n=231) matched for age and sex to the general population of their community (OR=3.4, 95%CI 1.9-6.2). Dentists (26%), healthcare assistants…
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