Result for
Topic: Clinical Characteristics and Health Care Setting
September 24, 2020
Outcomes of the 2019 Novel Coronavirus in Patients with or without a History of Cancer: A Multi-Centre North London Experience
Cancer diagnosis did not increase risk of death (OR: 1.05, 95% CI: 0.4-2.5) or severe outcomes (OR: 0.9, 95% CI: 0.7-24.0) among a matched cohort of hospitalized patients with COVID-19 (n=120). Cancer patients who had received systemic treatment within 28 days prior to hospital admission appeared to have a nonsignificantly increased risk of death (OR:…
The Incidence, Risk Factors, and Prognosis of Acute Kidney Injury in Adult Patients with Coronavirus Disease 2019
In a retrospective cohort study in China, 7% of 1,392 COVID-19 patients developed acute kidney injury (AKI) during hospitalization. In-hospital mortality was higher among patients with AKI even after adjustment for confounders (OR: 5.1; 95% CI: 2.7-9.7). Cheng et al. (Sept 22, 2020). The Incidence, Risk Factors, and Prognosis of Acute Kidney Injury in Adult…
Association of SARS-CoV-2 Test Status and Pregnancy Outcomes. JAMA. https://doi.org/10.1001/jama.2020.19124
In a Swedish study conducted among pregnant women in labor, 5.8% of 2,682 women tested positive for SARS-CoV-2 via RT-PCR. Positive patients were more likely to have preeclampsia (7.7% vs 4.3%; PR: 1.8; 95% CI: 1.0-3.4) and less likely to undergo induction of labor (18.7% vs 29.6%; PR: 0.6; 95% CI: 0.45-0.9). Other maternal and…
September 23, 2020
Risk of Adverse COVID-19 Outcomes for People Living with HIV a Rapid Review and Meta-Analysis
[Pre-print, not peer-reviewed] Pooled results from 5 studies (median sample size 55 [IQR 35-115]) showed that people living with HIV had a 1.9-fold higher risk of COVID-19 mortality (95%CI 1.6-2.3) compared to people without HIV. Two studies reported that tenofovir-based antiretroviral therapy regimens were associated with a lower risk of adverse COVID-19 outcomes, but the…
Risk Factors for Hospitalization, Mechanical Ventilation, or Death Among 10 131 US Veterans With SARS-CoV-2 Infection
In a national cohort of 88,747 veterans in the US, 11% tested positive for SARS-CoV-2 from February to May 2020. Veterans with positive PCR results were predominantly male (91%) with a mean age of 64 (SD=16) years. Positive patients had increased rates of 30-day hospitalization (aHR=1.1), mechanical ventilation (aHR=4.2), and death (aHR=4.4). Among positive patients,…
Association of Red Blood Cell Distribution Width With Mortality Risk in Hospitalized Adults With SARS-CoV-2 Infection
An elevated level of red blood cell distribution width (RDW, >14.5%) at hospital admission was associated with an increased mortality risk among 1,461 patients diagnosed with SARS-CoV-2 infection in Boston (RR=2.7). In addition, patients whose RDW increased during hospitalization had higher mortality compared with those whose RDW did not change (6% vs 24% among 1,173…
Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Infection Among VA Healthcare System Employees Suggests Higher Risk of Infection When Exposed to SARS-CoV-2 Outside of the Work Environment
Among Veterans Affairs Healthcare System employees (n=2,900), those who reported direct contact with someone with COVID-19 outside of work were more likely to have SARS-CoV-2 antibodies. Facility-wide testing (June 8 to July 8, 2020) identified 5% of employees (n=1,476) of a Veterans Affairs Healthcare System tested positive for SARS-COV-2 IgG antibodies, of whom 29% reported…
September 22, 2020
Tracing Asymptomatic SARS-CoV-2 Carriers among 3674 Hospital Staff: A Cross-Sectional Survey
A single-center cross-sectional study of hospital staff in Wuhan, China tested all staff members who did not have clinical symptoms of COVID-19 (n=3,764) and found that 126 (3%) hospital staff had findings consistent with SARS-CoV-2 infection. These included 61 (2%) with anti-SARS-CoV-2 IgG antibodies, 37 (1%) with chest CT findings consistent with COVID-19, and 28…
Racial and Ethnic Disparities in COVID‐19 Infections and Deaths across U.S. Nursing Homes
A national study of 12,576 nursing homes indicated that nursing homes caring for disproportionately more racial/ethnic minority residents tended to have more new COVID-19 confirmed cases among their residents and staff and more new COVID-19 related deaths among residents. The number of weekly new COVID-19 confirmed cases among residents increased with higher nursing home proportion…
Nasopharyngeal SARS-CoV2 Viral Loads in Young Children Do Not Differ Significantly from Those in Older Children and Adults
[Pre-print, not peer-reviewed] A multicenter investigation of >5,000 patients with confirmed SARS-CoV-2 infection found no significant difference in the amount of viral nucleic acid in nasopharyngeal swabs between young children and adults. Viral loads were comparable between children under 5, older children, and adults. Madera et al. (Sept 22, 2020). Nasopharyngeal SARS-CoV2 Viral Loads in…
Previous page Next page