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Topic: Clinical Characteristics and Health Care Setting
August 18, 2020
Risk Factors for COVID-19-Related Mortality in People with Type 1 and Type 2 Diabetes in England: A Population-Based Cohort Study
Analysis of a cohort study of people diagnosed with type 1 and type 2 diabetes registered with a general practice in England found that weekly death registrations in the first 19 weeks of 2020 exceeded corresponding 3-year weekly averages by 51% among people with type 1 diabetes and by 64% among people with type 2 diabetes. Male sex, older age,…
Association Between Youth Smoking, Electronic Cigarette Use, and Coronavirus Disease 2019
A national survey of adolescents and young adults in the US (n=4,351) aged 13-24 found that COVID-19 diagnosis was associated with ever-use of e-cigarettes (aOR=5.1), ever dual use of e-cigarettes and cigarettes (aOR=7.0), and past 30-day dual use (aOR=6.8). Gaiha et al. (Aug 11, 2020). Association Between Youth Smoking, Electronic Cigarette Use, and Coronavirus Disease 2019. Journal of Adolescent Health. https://doi.org/10.1016/j.jadohealth.2020.07.002
August 17, 2020
Cerebral Micro-Structural Changes in COVID-19 Patients – An MRI-Based 3-Month Follow-up Study
A study of patients with COVID-19 (n=60) in Fuyang, China found that 68% had neurological symptoms during infection and 55% still had symptoms 3 months after infection. Brain imaging identified a variety of significantly different neurological characteristics between COVID-19 patients and non-COVID-19 volunteers (n=39) that could be relevant to long-term consequences of SARS-CoV-2. Lu et al. (Aug 3, 2020). Cerebral Micro-Structural Changes in COVID-19 Patients – An MRI-Based 3-Month…
August 14, 2020
Associations of Type 1 and Type 2 Diabetes with COVID-19-Related Mortality in England: A Whole-Population Study
A study of all adults registered with a general practice in England (n=61,414,470) found a 2.9-fold higher likelihood of in-hospital COVID-19 related death among those with for type 1 diabetes and 1.8-fold higher likelihood among those with type 2 diabetes compared to other patients, after adjustment for confounders. The unadjusted risk difference for COVID-19 related mortality was…
Racial and Ethnic Disparities in SARS-CoV-2 Pandemic: Analysis of a COVID-19 Observational Registry for a Diverse US Metropolitan Population
A cross-sectional analysis of the COVID-19 Surveillance and Outcomes Registry, which captures data for a large healthcare system in the Houston area, reported a 7% test positivity. After adjustment for confounders, compared to non-Hispanic whites, test positivity was higher among non-Hispanic Black individuals (OR=2.2) and those of Hispanic ethnicity (OR=1.95). Using structural equation modeling, the authors demonstrated a significant indirect effect of…
Characteristics and Outcomes of COVID-19 Patients During Initial Peak and Resurgence in the Houston Metropolitan Area
A review of patients with confirmed COVID-19 in Houston, Texas during the initial peak and resurgence of COVID-19 (up to July 7) found that during the resurgence, patients were younger, more likely to be Hispanic, more likely to reside in a zip code with lower median income, and less likely to have general and specific…
Association Between Number of In-Person Health Care Visits and SARS-CoV-2 Infection in Obstetrical Patients
A nested case-control study among obstetrical patients delivering at four hospitals in Boston found that there was no meaningful difference between the number of in-person visits for case patients with SARS-CoV-2 versus controls (mean 3.3 visits versus 3.1). All patients in the study were tested for SARS-CoV-2 on admission. Cases were matched with up to 5 controls…
August 13, 2020
Novel Use of Home Pulse Oximetry Monitoring in COVID‐19 Patients Discharged From the Emergency Department Identifies Need for Hospitalization
Shah et al. assessed the use of home pulse oximetry as a monitoring tool to identify the need for hospitalization among 77 patients with initially non-severe COVID-19 in Chicago, including 22 (29%) who subsequently required hospitalization. They found that low resting oxygen saturation (SpO2 <92%) was associated with an increased likelihood of hospitalization (RR=7.0, 95%CI 3.4-14.5). Half of patients who required hospitalization had SpO2 < 92% without worsening symptoms. Shah et al….
Comparison of Estimated Excess Deaths in New York City During the COVID-19 and 1918 Influenza Pandemics
During the early phase of the COVID-19 outbreak in New York City (61 days, March 11-May 11, 2020) the all-cause mortality rate (202 per 100 000 person-months) was 4.2-fold higher than corresponding periods in 2017-2019. In comparison, during the peak of the 1918 H1N1 influenza outbreak (61 days in October-November 1918), the all-cause mortality (287 per 100 000 person-months) was 2.8 times higher than corresponding periods in 1914-1917. Faust et al. (Aug…
August 12, 2020
Association of Mental Disorders with SARS-CoV-2 Infection and Severe Health Outcomes a Nationwide Cohort Study
[pre-print, not peer-reviewed] A matched (age, sex, Charlson comorbidity index) cohort study of individuals tested for COVID-19 in Korea (n=122,722) found no evidence of association between a diagnosis of mental illness in the preceding 6 months and COVID-19 test positivity. A subgroup analyses found those with schizophrenia-related disorders had a higher likelihood of test positivity (OR=1.36, 95%CI 1.02-1.81). Restricted…
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