Result for
Topic: Clinical Characteristics and Health Care Setting
April 17, 2020
Sequential analysis of viral load in a neonate and her mother infected with SARS-CoV-2
The authors report on changes in viral load over time in a 27-day old neonate diagnosed with COVID-19 who presented with fever, cough and vomiting. SARS-CoV-2 RNA was detected in all clinical specimens (nasopharynx, oropharynx, stool, saliva, blood and urine) with the highest viral load found in the nasopharynx, which decreased over time, while viral…
Survival After In-Hospital Cardiac Arrest In Critically Ill Patients-Implications for the COVID-19 Pandemic?
Girotra et al conducted a simulation study and used survival data of 5,690 patients hospitalized in ICU with a diagnosis of pneumonia or sepsis, and who were receiving mechanical ventilation at the time of cardiac arrest during 2014-2018 to understand survival outcomes in severe COVID-19 patients. They found that survival outcomes following in-hospital resuscitation were…
April 16, 2020
The impact of COPD and smoking history on the severity of Covid-19: A systemic review and meta-analysis
A comprehensive systematic literature search to explore the risk of COVID-19 in patients with pre-existing chronic obstructive pulmonary disease (COPD) and ongoing smoking history indicates that COPD and ongoing smoking attribute to the worse progression and outcomes of COVID-19. Zhao et al. (Apr 15, 2020). The impact of COPD and smoking history on the severity…
Clinical characteristics of 3,062 COVID-19 patients: a meta-analysis
A meta-analysis of clinical characteristics of 3,062 COVID-19 patients suggest that fever, fatigue, cough and expectoration were the most commonly experienced symptoms of COVID-19 patients. A relatively small percentage of patients were asymptomatic. Most patients showed normal leucocytes counts, lymphopenia, elevated levels of C-reactive protein and ESR. Bilateral lungs involvement was common. Zhu et al….
Incidence, clinical outcomes, and transmission dynamics of hospitalized 2019 coronavirus disease among 9,596,321 individuals residing in California and Washington, United States: a prospective cohort study
This study of 1,277 hospitalized, COVID-19 patients who resided in CA or WA and had Kaiser Permanente insurance identified these key characteristics: (1) older and male patients were more likely than younger or female patients to be admitted to the ICU and to die, (2) an 11-day average duration of stay for hospitalized patients and…
Cardiovascular Diseases and COVID-19 Mortality and Intensive Care Unit Admission: A Systematic Review and Meta-analysis
In a systematic review and meta-analysis of 16 papers including 3,473 patients, Shamshirian et al find that acute cardiac injury, hypertension, heart failure and overall cardiovascular diseases were significantly associated with mortality and disease severity in COVID-19 patients. COVID-19 patients need to be carefully monitored for CVD and managed properly in case of acute cardiac…
April 15, 2020
Pregnancy outcomes, Newborn complications and Maternal-Fetal Transmission of SARS-CoV-2 in women with COVID-19: A systematic review
A systematic review was conducted by Gajbhiye et al. on published articles on maternal and fetal outcomes in pregnant women with COVID-19 and the incidence of maternal-fetal transmission. Most common co-morbidities in women included diabetes, hypertensive disorders, and placental disorders, and in neonates included preterm birth, respiratory distress syndrome, pneumonia, and low birth weight (all…
April 14, 2020
C-reactive protein correlates with CT findings and predicts severe COVID-19 early
Clinical parameters from 27 consecutive COVID-19 patients and 75 flu patients at initial, progression, peak, and recovery stages of illness were analyzed. The authors found that C-reactive protein in severe COVID-19 patients increased significantly at the initial stage, prior to CT findings, and suggest that this could be used as an early predictor of severe…
Characteristics of Health Care Personnel with COVID-19 — United States, February 12–April 9, 2020
The CDC presents characteristics from 9,282 cases of COVID-19 reported among US HCP. Most HCP were not hospitalized, however severe outcomes, including death, were reported among all age groups. Burrer et al. (April 14, 2020). Characteristics of Health Care Personnel with COVID-19 — United States, February 12–April 9, 2020. MMWR. https://www.cdc.gov/mmwr/volumes/69/wr/pdfs/mm6915e6-H.pdf
Impact of Social Vulnerability on COVID-19 Incidence and Outcomes in the United States
This study found that each percentile increase in county-level social vulnerability to disasters, measured using the Social Vulnerability Index, was associated with a 63% higher case fatality rate (CFR) after adjusting for other factors. Both CFR and incidence of COVID-19 were significantly higher in counties with lower socio-economic status and higher proportion of minority populations….
Previous page Next page