Result for
Topic: Clinical Characteristics and Health Care Setting
April 27, 2021
Fatigue Symptoms Associated with COVID-19 in Convalescent or Recovered COVID-19 Patients a Systematic Review and Meta-Analysis
[Pre-print, not peer-reviewed] Fatigue was more 3.7-fold as common among patients recovering from COVID-19 compared to healthy controls, according to a systematic review of 39 studies (n=8,825 patients). Over half of hospitalized patients reported symptoms of fatigue up to two months after discharge. Female gender was associated with greater self-reported fatigue and self-report of fatigue…
Risk Factors for Long Covid in Previously Hospitalised Children Using the ISARIC Global Follow-up Protocol A Prospective Cohort Study
[Pre-print, not peer-reviewed] 24% of children hospitalized with COVID-19 in Moscow, Russia reported persistent symptoms at approximately 1 year post-discharge (n=518; median age 10 years). The most commonly reported symptoms were fatigue, followed by sleep disturbance and sensory problems. Persistent symptoms were more common among those aged 6-18 years compared to patients aged <2 years,…
6-Month Follow Up of 8679 Hospitalized COVID-19 Patients in Germany A Nationwide Cohort Study
[Pre-print, not peer-reviewed] 180-day mortality was 30% in a large cohort (n=8,679; median age 72 years) from Germany hospitalized with COVID-19 from February to April 2020. 180-day mortality was 52% among patients aged ≥80 years and 53% for patients who had undergone invasive mechanical ventilation. Coagulopathy, BMI ≥ 40, and age were risk factors for…
Genomic Epidemiology of SARS-CoV-2 Infection During the Initial Pandemic Wave and Association With Disease Severity
The SARS-CoV-2 D614G variant was associated with increased survival in hospitalized patients (86% vs 59% for other identified variants) according to analysis from a repeated cross-sectional study (n=302) of SARS-CoV-2 isolates from the Cleveland Clinic during the first wave of infection (March to April 2020). While 6 different clades were initially identified in the beginning…
Impaired Diffusing Capacity for Carbon Monoxide Is Common in Critically Ill Covid-19 Patients at Four Months Post-Discharge
Impaired lung function was present in 52% of COVID-19 patients four months after discharge from the ICU from March to July 2020 (n=60). The most prevalent impairment was lower than normal diffusing capacity for carbon monoxide (DLCO) (45%). Impaired DLCO was more common among those aged >60 years and those who received invasive mechanical ventilation…
April 23, 2021
Does Taking an Angiotensin Inhibitor Increase the Risk for COVID-19? – A Systematic Review and Meta-Analysis
A systematic review and meta-analysis found no association between angiotensin inhibitor (ACE) use and COVID-19 severity or mortality. The authors suggest that these data may indicate that the presence of hypertension, rather than the use of ACEs, is a greater risk factor for severe COVID-19 outcomes. The authors conclude that there is no evidence to…
Preexisting and New-Onset Diabetes in Patients with COVID-19 Pneumonia
[Pre-print, not peer-reviewed] A single-center study of patients admitted for COVID-19 pneumonia with diabetes (N=176) found that having new-onset diabetes was associated with higher risk of ICU admission and death and a longer time to viral clearance compared to having a preexisting diagnosis of diabetes. Nearly 30% of patients with new-onset diabetes did not have…
The Global Case-Fatality Rate of COVID-19 Has Been Declining Since May 2020
A retrospective evaluation of WHO SARS-CoV-2 daily situation reports data found that the global cumulative reported case fatality rate (rCFR) reached a peak of 7.2% during the week of April 22-28, 2020 before declining to 2.2% in December 28-31, 2020. The decline in rCFR was not associated with an increase in tests performed. However, county-level…
Health Care Utilization and Clinical Characteristics of Nonhospitalized Adults in an Integrated Health Care System 28 – 180 Days After COVID-19 Diagnosis — Georgia, May 2020–March 2021
Among adult patients with SARS-CoV-2 who were not hospitalized and who were enrolled in an integrated health system in Georgia, approximately two thirds had at least 1 outpatient medical encounter 28–180 days after diagnosis, and approximately two thirds of these persons received a new primary diagnosis at one or more visits. New diagnoses included cough,…
April 22, 2021
Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study
In an international cohort study, pregnant women with COVID-19 (n=706) were at increased risk for preeclampsia/eclampsia, severe infections, ICU admissions, preterm birth, severe neonatal morbidity and severe perinatal morbidity and mortality compared to those without a COVID-19 diagnosis (n=1,424). Asymptomatic SARS-CoV-2 infection was only associated with increased risk for maternal morbidity and preeclampsia. 13% of…
Previous page Next page