Result for
Topic: Clinical Characteristics and Health Care Setting
February 24, 2020
SARS-CoV-2 infection does not significantly cause acute renal injury: an analysis of 116 hospitalized patients with COVID-19 in a single hospital, Wuhan, China
In contrast to recent papers citing elevated incidence of renal abnormalities among COVID-19 patients, this hospital-based study of 116 patients did not find evidence that COVID-19 is associated with acute renal injury or aggravated chronic renal failure. Wang et al. (Feb 23, 2020). SARS-CoV-2 infection does not significantly cause acute renal injury: an analysis of…
The efficacy of convalescent plasma for the treatment of severe influenza
Authors conducted a meta-analysis of five RCTs in which convalescent plasma was used to treat severe influenza. The mixed results suggest further study is needed to determine if administration of convalescent plasma may be an effective treatment regimen for COVID-19. Xu et al. (Feb 23, 2020). The efficacy of convalescent plasma for the treatment of…
The cross-sectional study of hospitalized coronavirus disease 2019 patients in Xiangyang, Hubei province
Clinical information for 102 hospitalized COVID-19 patients are provided and authors provide recommendations for a three-week quarantine period. They also suggest that for the best testing sensitivity, diagnosis should include three real-time RTP-PCR tests and two CT scans, though they do not comment on resource constraints. Ai et al. (Feb 23, 2020). The cross-sectional study…
February 21, 2020
Clinical Characteristics and Progression of 2019 Novel Coronavirus-1 Infected Patients 2 Concurrent Acute Respiratory Distress Syndrome
Clinical characteristics are described for 109 COVID-19 patients admitted to Central Hospital of Wuhan. Patients with acute respiratory distress syndrome (ARDS) were more likely to have co-existing conditions, such as diabetes and cerebrovascular and chronic kidney disease than patients without ARDS. Severity of ARDS was also associated with higher risk of death. Liu et al….
Kidney impairment is associated with in-hospital death of COVID-19 patients
A study of 710 COVID-19 patients found elevated prevalence of kidney impairment and a higher risk of in-hospital death among those with kidney impairment. Cheng et al. (Feb 20, 2020). Kidney impairment is associated with in-hospital death of COVID-19 patients. Pre-print downloaded Feb 21 from https://doi.org/10.1101/2020.02.18.20023242
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study
Among critically ill COVID-19 pneumonia patients, mortality is high, especially for those with comorbidities. Survival after ICU admission appears to be around 1-2 weeks among these patients. Yang et al. (Feb 21, 2020). Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. The Lancet Respir…
February 20, 2020
Chloroquine for the 2019 novel coronavirus
Colson et al. recommend investigation into the potential antiviral properties of drugs which have been proven to be harmless and whose pharmacokinetics and optimal dosage are well-known, including chloroquine phosphate. Colson et al. (Feb 15, 2020). Chloroquine for the 2019 novel coronavirus. Int J of Antimicrobial Agents. https://doi.org/10.1016/j.ijantimicag.2020.105923
Outbreak of novel coronavirus (COVID-19): What is the role of radiologists?
The author outlines the roles of a radiologist in clinical setting during the COVID-19 outbreak. Kim (Feb 18, 2020). Outbreak of novel coronavirus (COVID-19): What is the role of radiologists? European Radiology. https://doi.org/10.1007/s00330-020-06748-2
Initiation of a new infection control system for the COVID-19 outbreak
This commentary describes initiation of a new infection control system for the COVID-19 outbreak in China in light of pneumonia of unknown origin. Chen et al. (Feb 18, 2020). Initiation of a new infection control system for the COVID-19 outbreak: The Lancet Infectious Diseases. https://doi.org/10.1016/S1473-3099(20)30110-9
Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series
Xu et al. report on clinical findings in a group of COVID-19 patients outside of Wuhan, China. They report that as of Feb 2020, compared with patients initially infected in Wuhan, the symptoms of patients in Zhejiang province are relatively mild. Xu et al. (Feb 19, 2020). Clinical findings in a group of patients infected…
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