Result for
Topic: Transmission
April 23, 2020
An ecological study of socioeconomic predictors in detection of COVID-19 cases across neighborhoods in New York City
Socioeconomic predictors that could explain the between-neighborhood variation in the number of detected COVID-19 cases in NYC in this ecological analysis include: neighborhoods with a large dependent population (under 18 or 65+ years), those with a high proportion of males, and low-income neighborhoods. Whittle & Diaz-Artiles (Apr 22, 2020). An ecological study of socioeconomic predictors…
No SARS-CoV-2 detected in amniotic fluid in mid-pregnancy
No SARS-CoV-2 was detected in the amniotic fluid of 2 pregnant women who were diagnosed with COVID-19 in the early stage of pregnancy in Wuhan. These findings could contribute to understanding the potential for intrauterine transmission in the first trimester. Yu et al. (Apr 22, 2020). No SARS-CoV-2 detected in amniotic fluid in mid-pregnancy. Lancet….
April 22, 2020
Connecting clusters of COVID-19: an epidemiological and serological investigation. Lancet Infectious disease (2020)
Yong et al describe how active case finding and contact tracing were used to identify cases and establish links between three clusters of COVID -19 in Singapore. The investigations used both SARS-CoV-2 serological assays and traditional epidemiological methods to confirm transmission between cases. This study is important to those establishing links among locally transmitted COVID-19…
April 21, 2020
Sequencing analysis of the spread of SARS-CoV2 in the Greater New York City Region
This analysis of 156 SARS-CoV-2 sequences from New York City showed that most samples were related to viral outbreaks in Europe, and suggest numerous seed transmissions and a period of unrecognized community spreading. Maurano et al. (April 21, 2020). Sequencing analysis of the spread of SARS-CoV2 in the Greater New York City Region. Pre-print downloaded…
Epidemiological and Genomic Analysis of SARS-CoV-1 2 in Ten Patients from a Mid-sized City outside of Hubei, China
This epidemiological and genomic analysis from 10 patients in Shaoxing led to an estimated average mutation rate of 1.37×10-3 nucleotide substitution per site per year, similar to other coronaviruses. The authors conclude that the moderate mutation rate lends hope to the development of an effective long-lasting vaccine. Chen et al. (April 21, 2020). Epidemiological and…
April 20, 2020
Population movement, city closure in Wuhan and geographical expansion of the 2019-nCOV pneumonia infection in China in January 2020
Using data on daily reported new cases and population movement during the month of January, Liu et al observe a significant positive association between population movement and the number of COVID-19 cases. Spatial distribution of cases indicate that some areas with large outflow (i.e. Henan and Hunan) might have been underestimated in disease spread. The…
SARS-CoV-2 RNA Found on Particulate Matter of Bergamo in Northern Italy: First Preliminary Evidence
Setti et al share some preliminary evidence that SARS-CoV-2 RNA can be present on outdoor particulate matter (PM), indicating that the persistence of SARS-CoV-2 may be enhanced in conditions of atmospheric stability and high concentrations of PM. Further studies to assess the vitality and virulence of SARS-CoV-2 when adsorbed on PM are needed and correlations…
Breastfeeding of Infants Born to Mothers with COVID-19: A Rapid Review
Yang et al conduct a systematic review of case reports and series involving a total of 16 mothers with COVID-19 and 42 mothers with influenza to investigate mother-to-child transmission of SARS-Cov-2 during breastfeeding and conclude that current evidence indicates that SARS-CoV-2 viral nucleic acid has not been detected in breast milk. Based on these findings,…
April 17, 2020
Delayed clearance of SARS-CoV-2 in male compared to female patients: High ACE2 expression in testes suggests possible existence of gender-specific viral reservoirs
In this study, the authors evaluate the time to viral clearance in 68 symptomatic patients (71% males and 29% females), and report that females achieved viral clearance significantly earlier than males, with a median difference of 2 days. Shastri et al hypothesize that high expression of ACE2 in testes could indicate that testicular viral reservoirs…
April 16, 2020
Rapid surveillance of COVID-19 in the United States using a prospective space-time scan statistic: Detecting and evaluating emerging clusters
The authors use prospective space-time scan statistic methodology to detect emerging clusters of COVID-19 in the US and at the county level for 2 distinct time periods, and emphasize the importance of focusing surveillance on emerging and active clusters during epidemics. These timely results can inform public health officials and decision-makers about locations to prioritize…
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