Alliance for Pandemic Preparedness

Result for
Topic: Transmission


February 25, 2020

A descriptive study of the impact of diseases control and prevention on the epidemics 1 dynamics and clinical features of SARS-CoV-2 outbreak in Shanghai, lessons learned for 2 metropolis epidemics prevention

Lu et al (2020) evaluated the impact of disease control and prevention on epidemic dynamics and clinical features of the COVID-19 outbreak in Shanghai. They report a reduction in transmission of 99% within Shanghai and that the exponential growth had so far been stopped. They conclude that strict control of transmission at the early stage…


February 24, 2020

Notes from the Field: Investigation of a Cluster of 2019 Novel Coronavirus Disease (COVID-19) with Possible Transmission During the Incubation Period — Shenyang City, China, 2020

Transmission patterns within a small family cluster of COVID-19 cases suggest probably asymptomatic transmission from one person who travelled to Wuhan to other family members.  Wang et al. (Feb 21, 2020). Notes from the Field: Investigation of a Cluster of 2019 Novel Coronavirus Disease (COVID-19) with Possible Transmission During the Incubation Period — Shenyang City,…


Presumed Asymptomatic Carrier Transmission of COVID-19

A familial cluster of five COVID-19 patients appears to have contracted the disease after asymptomatic transmission from a family member who travelled to Wuhan.  Bai et al. (Feb 21, 2020). Presumed Asymptomatic Carrier Transmission of COVID-19. JAMA. https://jamanetwork.com/journals/jama/fullarticle/2762028?resultClick=1


Clinical Characteristics of 24 Asymptomatic Infections with COVID-19 Screened among Close Contacts in Nanjing, China

24 asymptomatic, laboratory-confirmed COVID-19 cases were identified via contact investigation in Nanjing. Five developed symptoms, twelve had abnormal CT, and seven had no symptoms and no abnormal CT during hospitalization. The seven cases were younger (med age 14 years). The median communicable period of all cases was 9.5 days but extended to up to 21….


The serial interval of COVID-19 from publicly reported confirmed cases

Estimates of the serial interval (time between symptom onset in index case and symptom onset in secondary case) for COVID-19 in China suggest possible pre-symptomatic transmission.  Du et al. (Feb 23, 2020). The serial interval of COVID-19 from publicly reported confirmed cases. Pre-print downloaded Feb 24 from https://doi.org/10.1101/2020.02.19.20025452 


Estimating the Asymptomatic Ratio of 2019 Novel Coronavirus onboard the Princess Cruises Ship, 2020

Researchers estimated that 34.6% (95% CI: 24.9%-39.8%) of COVID-19 cases on the Princess Cruises Ship docked off the coast of Yokohama, Japan, were asymptomatic, with most infections occurring prior to the start of the 2-week on-board quarantine. Mizumoto et al. (Feb 23, 2020). Estimating the Asymptomatic Ratio of 2019 Novel Coronavirus onboard the Princess Cruises…


Estimating the case fatality ratio of the COVID-19 epidemic in China

A new study estimates the case fatality risk in Wuhan to be 8.71% (95% CI: 79.5%-9.64%) compared to 1.21% (95% CI: 1.07%-1.40%) in other areas of China.  Wang et al. (Feb 22, 2020). Estimating the case fatality ratio of the COVID-19 epidemic in China. Pre-print downloaded Feb 23 from https://doi.org/10.1101/2020.02.17.20023630 


February 21, 2020

Estimating number of global importations of COVID-19 from Wuhan, risk of transmission outside mainland China and COVID-19 introduction index between countries outside mainland China

Accounting for potential unrecorded migration, these authors estimate the scope of COVID-19 importations in countries outside of China. They compare reported and estimated number of cases and describe countries that may be at elevated risk of local transmission. The U.S. is among the countries with higher estimated risk of a local outbreak.  Sun et al….


COVID-19 in Singapore—Current Experience: Critical Global Issues That Require Attention and Action

Singapore’s proactive public health response to COVID-19 is described with reference to seven critical issues that require global attention to further curb the spread of the outbreak. Among these are improved understanding of the epidemiological and clinical features of the virus, identification of effective treatment options and vaccines, and better communication and support strategies for…


February 20, 2020

COVID-19, Australia: Epidemiology Report 2

This report for the week ending Feb 8, 2020 includes data on 15 Australian cases with reported travel history to mainland China.  Walker (Feb 12, 2020). COVID-19, Australia: Epidemiology Report 2: Communicable Diseases Intelligence. https://doi.org/10.33321/cdi.2020.44.14



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