Result for
Topic: Transmission
February 20, 2020
symptomatic cases in a family cluster with SARS-CoV-2 infection
Pan et al. describe asymptomatic cases in a family cluster with SARS-CoV-2 infection. Such asymptomatic patients may not isolate themselves or seek treatment and may unknowingly transmit infection. Pan et al. (Feb 19, 2020). Asymptomatic cases in a family cluster with SARS-CoV-2 infection. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30114-6
2019 Novel coronavirus: where we are and what we know
Cheng and Shan provide COVID-19 outbreak overview, including reports from outbreak sites and laboratories supporting the investigation. The paper aggregates and consolidates the virology, epidemiology, clinical management strategies from both English and Chinese literature. From their single-term exponential model, they report that the infection is spreading at an exponential rate, with a doubling period of…
An interactive web-based dashboard to track COVID-19 in real time
Dong et al. introduce a public, online interactive dashboard hosted by the Center for Systems science and Engineering (CSSE) at Johns Hopkins University to visualize and track reported cases of COVID-19. Data from China CDC and WHO for confirmed cases inside and outside China are included. Dong et al. (Feb 19, 2020). An interactive web-based…
Enteric involvement of coronaviruses: is faecal–oral transmission of SARS-CoV-2 possible?
Yeo et al. provide evidence from previous outbreaks to support fecal-oral transmission of SARS-CoV and MERS-CoV and that they can remain viable in different environmental conditions that could facilitate fecal-oral transmission. It is possible that 2019-nCoV could also be transmitted via this route. They advocate for research on the possibility of fecal-oral transmission of 2019-nCoV…
February 19, 2020
Evaluating new evidence in the early dynamics of the novel coronavirus COVID-19 outbreak in Wuhan, China with real time domestic traffic and potential asymptomatic transmissions
Using information from evacuees from Wuhan and domestic traffic, authors explore the early dynamics of the COVID-19 outbreak and the potential role of asymptomatic transmission. The study did not find strong evidence of asymptomatic transmission but does not rule it out. Additional model findings are described. Zhou (Feb 18, 2020). Evaluating new evidence in the…
Estimating the Case Fatality Risk of COVID-19 using Cases from Outside China
Using data for symptomatic COVID-19 cases occurring outside of China and in countries with 20+ cases, researchers estimated the case fatality risk for COVID-19 cases outside of China to be about 1.4% (95% CI: 0.57%-3.22%) Wilson et al. (Feb 18, 2020). Estimating the Case Fatality Risk of COVID-19 using Cases from Outside China. Pre-print downloaded…
February 18, 2020
First imported case of 2019 novel coronavirus in Canada, presenting as mild pneumonia
The first imported case of COVID-19 was identified in Canada. The authors describe the mild clinical presentation and discuss the possibility of home isolation for mild cases. Silverstein (Feb 13, 2020). First imported case of 2019 novel coronavirus in Canada, presenting as mild pneumonia. The Lancet. https://doi.org/10.1016/S0140-6736(20)30370-6
Estimating underdetection of internationally imported COVID-19 cases
Researchers estimated that the global capacity to detect imported cases of COVID-19 is about 38% that of Singapore, which has historically had strong disease detection capacity. High surveillance countries have about 40% Singapore’s detection capacity compared to 37% in intermediate surveillance countries and 11% in low surveillance countries. If all countries had the same detection…
Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (COVID-19)
Researchers estimate that prior to the Wuhan travel shutdown (Jan 23, 202), 86% of all COVID-19 infections were undocumented. They also estimate that these undocumented cases were about half as contagious as documented infection. Undocumented cases prior to the Wuhan quarantine likely explain the rapid geographic spread of the virus. Li et al. (Feb 17,…
Estimation of the asymptomatic ratio of novel coronavirus infections (COVID-19)
Using data on Japanese travelers evacuated from Wuhan, researchers estimate the proportion of infected COVID-19 patients who are asymptomatic (asymptomatic ratio). Recognizing the limitations of the data used in their estimation, the authors conclude that as many as half of all COVID-19 cases may be asymptomatic. Nishiura et al. (Feb 17, 2020). Estimation of the…
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