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Evidence Base
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Evidence Base: Thyroid
Precision: Assessing the presence of a goiter
This is compiled data on the accuracy of exam findings for presence and absence of goiter, with US as gold standard. If goiter is present on physical exam, there is a LR+ of 3.8. If goiter is absent, there is a LR- of 0.37. The sensitivity and specificity of exam for goiter are also given.
| |
INTEROBSERVER |
INTRAOBSERVER |
| Study |
Kappa |
Study |
Kappa |
| INSPECTION |
Kilpatrick |
0.77 |
Hennessy |
0.82 |
| Dingle |
0.38 |
MacLennan |
|
COMBINED
95% CI |
0.65
(0.62-0.69) |
COMBINED
(95% CI) |
0.73
(0.71-0.76) |
| PALPATION |
Kilpatrick |
0.76 |
Hennessy |
0.79 |
| Dingle |
0.60 |
MacLennan |
0.47 |
COMBINED
95% CI |
0.74
(0.67-0.82) |
COMBINED
(95% CI) |
0.65
(0.63-0.67) |
| *Adapted from Siminoski et al. |
|
