November 4, 2020

SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study

Category: Article Summary

Topic: Clinical Characteristics and Health Care Setting

Keywords (Tags): candidate, children, report, risk factors, summarize, summarized as preprint

A prospective cohort study in North Carolina found that 77% of children and adolescents living with a close household contact infected with SARS-CoOV-2 had a positive SARS-COV2 PCR test. Hispanic ethnicity (OR=1.5) and having an infected sibling close contact (OR=1.7) were associated with increased infection risk. One or more symptoms were reported by 70% of children who were positive for SARS-CoV-2. Children ages 6-13 years were frequently asymptomatic (39%) and less likely to report respiratory symptoms than younger children ages 0-5 years or adolescents ages 14-20 years (29% vs. 48% and 60%, respectively). No difference was found in viral load between various age cohorts. [EDITORIAL NOTE: A pre-print version of this article was summarized on August 24]

Hurst et al. (Nov 3, 2020). SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa1693