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March 5, 2020
Air, Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient
An environmental hygiene study was conducted at a COVID-19 outbreak center in Singapore. Samples included surface samples taken at 26 sites, air samples, and PPE samples from physicians leaving patient rooms. Authors also describe sampling results post-cleaning. Overall, contamination via respiratory droplets and fecal shedding were a primary concern with findings emphasizing the importance of…
Covert COVID-19 and false-positive dengue serology in Singapore
A COVID-19 patient in Singapore was initially misdiagnosed by a false-positive dengue rapid test, underscoring the importance of formalizing rapid and accessible diagnostic tests with high sensitivity and specificity. Yan et al. (Mar 4, 2020). Covert COVID-19 and false-positive dengue serology in Singapore. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30158-4
Uncertainties about the transmission routes of 2019 novel coronavirus
COVD-19 transmission pathways remain only partially understood. This commentary reviews what is known and what is still under study. Han et al. (Mar 4, 2020). Uncertainties about the transmission routes of 2019 novel coronavirus. Influenza and Other Respiratory Viruses. https://doi.org/10.1111/irv.12735
Epidemiology and Transmission of COVID-19 in Shenzhen China: Analysis of 391 cases and 1,286 of their close contacts
This report summarizes the epidemiology of 391 COVID-19 patients in Shenzhen China and 1,286 close contacts. Rather than reporting on cases identified through symptom surveillance, this study offers a better estimation of how COVID-19 looks more broadly in the population by relying on contact tracing. In addition to clinical details, findings indicate that household contacts…
Monitoring Disease Transmissibility of 2019 Novel Coronavirus Disease in Zhejiang, China
Social distancing measures in Zhejiang Province appear to have reduced COVID-19 transmission. Authors suggest the study findings may be particularly relevant to high-risk regions. Chong et al. (Mar 5, 2020). Monitoring Disease Transmissibility of 2019 Novel Coronavirus Disease in Zhejiang, China. Pre-print downloaded Mar 5 from https://doi.org/10.1101/2020.03.02.20028704
March 4, 2020
COVID-19 Epidemic Outside China: 34 Founders and Exponential Growth
As COVID-19 cases continue to appear in new countries around the world, researchers have begun trying to map the spread of the disease outside of China. In this modelling study, researchers estimate that there were 34 unobserved “founder” patients that likely seeded spread outside China. Li et al (March 3, 2020). COVID-19 Epidemic Outside China:…
Stepping up infection control measures in ophthalmology during the novel coronavirus outbreak: an experience from Hong Kong
This report discusses the infection control measures implemented in an ophthalmology clinic in Hong Kong, based on a detailed risk assessment. A three-level process was adopted to protect the health and safety of both patients and staff. Lai et al. (Mar 3, 2020). Stepping up infection control measures in ophthalmology during the novel coronavirus outbreak:…
COVID-19: a novel coronavirus and a novel challenge for critical care
Arabi et al discuss implications and recommendations for intensive and critical care settings, including surge capacity, infection prevention and control, and staff protection. Arabi et al. (Mar 3, 2020). COVID-19: a novel coronavirus and a novel challenge for critical care. Intensive Care Medicine. https://doi.org/10.1007/s00134-020-05955-1
The Impact of the COVID-19 Outbreak on the Medical Treatment of Chinese Children with Chronic Kidney Disease (CKD): A Multicenter Cross-section Study in the Context of a Public Health Emergency of International Concern
An online survey was distributed to 17 pediatric nephropathy diagnosis and treatment centers in China to gather information on patients, parents, and changes to medical treatment processes since the start of the COVID-19 outbreak. Greatest needs reported by patients and families included online consultation, medication delivery, and psychological counselling, especially for low income children in…
Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China
In a study of 150 COVID-19 patients in Wuhan, case fatality was associated with older age, underlying comorbidities, presence of secondary infection, and inflammatory indicators in the blood. Death may also be related to virus-activated “cytokine storm syndrome” or fulminant myocarditis. Ruan et al. (Mar 3, 2020). Clinical predictors of mortality due to COVID-19 based…
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