Article Summary
March 4, 2020
Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential
Xu et al discuss the potential clinical use of niclosamide, an FDA-approved anthelminthic, in treating COVID-19. Xu et al. (Mar 3, 2020). Broad Spectrum Antiviral Agent Niclosamide and Its Therapeutic Potential. ACS Infect Dis. https://doi.org/10.1021/acsinfecdis.0c00052
Priorities for the US Health Community Responding to COVID-19
Adalja et al discuss priorities for the US health care community in preparing for COVID-19. Priorities include reviewing and updating preparedness plans developed for prior epidemics, hospital and clinic readiness, rapid expansion of diagnostic testing capacity, and public health interventions to slow spread. Adalja et al. (Mar 4, 2020). Priorities for the US Health Community…
Potential impact of seasonal forcing on a SARS-CoV-2 pandemic
Seasonal variation among the four endemic coronaviruses was used to model seasonality of SARS-CoV-2 across a range of scenarios, regions, and populations. The combined effects of seasonal changes and infection control efforts may be partially responsible for reductions in incidence globally and should be taken into account when monitoring global COVID-19 transmission. Neher et al….
Clinical features and sexual transmission potential of SARS-CoV-2 infected female patients: a descriptive study in Wuhan, China
Researchers tested vaginal and anal swabs from the 35 female patients with COVID-19 and only one anal swab sample from one patient was positive for SARS-CoV-2. Findings suggest no risk of transmission through vaginal sex, though additional research is still needed. Cui et al. (Mar 3 , 2020). Clinical features and sexual transmission potential of…
March 3, 2020
Active Monitoring of Persons Exposed to Patients with Confirmed COVID-19 — United States, January–February 2020
In this MMWR, authors describe active monitoring in the US of people with confirmed exposures to COVID-19 patients. Burke et al. (Mar 3, 2020). Active Monitoring of Persons Exposed to Patients with Confirmed COVID-19 — United States, January–February 2020. http://dx.doi.org/10.15585/mmwr.mm6909e1
Vicarious traumatization in the general public, members, and non-members of medical teams aiding in COVID-19 control
Li et al gathered information on vicarious traumatization (VT) of frontline and non-frontline nurses and compared it to VT of the general public. VT symptoms include appetite changes, fatigue, sleep disturbance, difficulty with focus, irritability, numbness, fear, and despair. All three groups have experienced VT under the spread of COVID-19, with the general public reporting…
Mitigate the effects of home confinement on children during the COVID-19 outbreak
An estimated 220 million children have experienced home confinement in China during the COVID-19 outbreak. China has implemented its emergency home schooling plan, and courses online and via TV are available to mitigate some of the educational impact on children. While there can be some benefits to home confinement, including more family interaction and communication,…
A case of 2019 Novel Coronavirus in a pregnant woman with preterm delivery
The authors describe the case of a 30-week pregnant COVID-19 patient who underwent emergency cesarean section and delivered a healthy baby with no COVID-19 infection. Wang et al. (Feb 28, 2020). A case of 2019 Novel Coronavirus in a pregnant woman with preterm delivery. Clinical Infectious Diseases. https://doi.org/10.1093/cid/ciaa200
The persistence and clearance of viral RNA in 2019 novel coronavirus disease survivors
RT-PCR results for biological samples of 66 recovering COVID-19 patients were used to evaluate SARS-CoV-2 clearance time and influencing factors. Viral clearance in stool samples was delayed compared to oropharyngeal swabs. Furthermore, this delay was pronounced among patients who were treated with corticosteroids, suggesting that treatment with corticosteroids should be considered with caution. Ling et…
Coronavirus disinfection in histopathology
This paper offers recommendations for laboratory safety and disinfection methods for use in histotechnology processes. Henwood (Mar 1, 2020). Coronavirus disinfection in histopathology. Journal of Histotechnology. https://doi.org/10.1080/01478885.2020.1734718
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