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Tag: children
November 16, 2020
Changes in Pediatric Emergency Department Visits for Mental Health during the COVID-19 Pandemic: A Cross-Sectional Study
In a cross-sectional study conducted at a children’s hospital in Connecticut, there was a 60.8% reduction in children presenting to emergency departments with mental health-related diagnoses during the early COVID-19 pandemic period compared to 2019. Black children were significantly less likely to present with a mental health condition than white children during the pandemic as…
November 10, 2020
The Role of Children in the Transmission Chain of SARS-CoV-2 a Systematic Review and Update of Current Evidence
[Pre-print, not peer reviewed] A systematic review and meta-analysis of 22 studies on the role of children in the SARS-CoV-2 transmission chain confirms that children are able to be infected and transmit SARS-CoV-2 in a variety of settings, with potentially different dynamics depending upon age. Transmission chains in which the index case was a child…
Characteristics and Outcomes of Neonatal SARS-CoV-2 Infection in the UK: A Prospective National Cohort Study Using Active Surveillance
A national prospective study in the UK found low incidence (5.6 per 10,000 live births) of neonatal SARS-CoV-2 infection. Of the 66 babies identified with SARS-CoV-2 during the study period, 17 (26%) babies were born to mothers with known perinatal SARS-CoV-2 infection, and only 2 (3%) were considered to have possible vertically acquired infection. The…
November 4, 2020
SARS-CoV-2 Infections Among Children in the Biospecimens from Respiratory Virus-Exposed Kids (BRAVE Kids) Study
A prospective cohort study in North Carolina found that 77% of children and adolescents living with a close household contact infected with SARS-CoOV-2 had a positive SARS-COV2 PCR test. Hispanic ethnicity (OR=1.5) and having an infected sibling close contact (OR=1.7) were associated with increased infection risk. One or more symptoms were reported by 70% of…
SARS-CoV-2 Detection by Nasal Strips a Superior Tool for Surveillance of Pediatric Populations
In pediatric patients, the use of small strips inserted into each nostril was shown to have a sensitivity of 94% and specificity of 100% for the detection of SARS-CoV-2 when compared to pooled nasopharyngeal swab and throat swab samples. Viral loads of SARS-CoV-2 RNA were similar between paired nasal strip samples and nasal swab samples….
October 26, 2020
Comparison of Upper Respiratory Viral Load Distributions in Asymptomatic and Symptomatic Children Diagnosed with SARS-CoV-2 Infection in Pediatric Hospital Testing Programs
Children with asymptomatic SARS-CoV-2 infection were found to have lower levels of virus in their nasopharynx/oropharynx than children with symptomatic infection, but timing of infection relative to diagnosis likely influenced levels in asymptomatic children. A study assessing Ct values and estimated viral load in children with asymptomatic versus symptomatic infection showed that the median adjusted…
October 23, 2020
Clinical and Epidemiologic Analysis of COVID-19 Children Cases in Colombia PEDIACOVID
At the national level in Colombia, pediatric patients with more severe COVID-19 were significantly younger than those who experienced mild illness or no symptoms. A retrospective analysis found that the mean age of children who had asymptomatic infection was 9.4 years compared to a mean of 4.9 years among those with severe infection and a…
October 20, 2020
Synthesis and Systematic Review of Reported Neonatal SARS-CoV-2 Infections
A systematic review and meta-analysis of neonatal case studies of SARS-CoV-2 infection (n=176) defined by at least one positive nasopharyngeal swab or presence of virus-specific IgM found that vertical transmission (mother-to-child) accounted for 30% SARS-CoV-2 infections and environmental exposure accounted for 70% of infections. 64% had abnormal lung imaging, 55% of neonates developed COVID-19, with…
October 16, 2020
COVID-19 Transmission in US Child Care Programs
In a study of COVID-19 outcomes among child care providers who provided in-person child care during the first three months of the pandemic versus those who did not, no association was found between exposure to child care and testing positive for or being hospitalized with COVID-19 in both unmatched (OR =1.06) and matched (OR=0.94) analyses….
Transmission of SARS-CoV-2 from Children and Adolescents
[Pre-print, not peer reviewed] Children and adolescents who acquired SARS-CoV-2 infection during an overnight camp in June transmitted the virus to both pediatric and adult contacts in their households, with 10% of the adult secondary cases requiring hospitalization, based on a retrospective cohort study from Georgia. Among 526 tested household contacts of 224 infected individuals,…
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