Result for
Tag: clinical characteristics
October 30, 2020
Case Fatality Rates for COVID-19 Patients Requiring Invasive Mechanical Ventilation: A Meta-Analysis
A meta-analysis of the case fatality ratio among adults with COVID-19 receiving invasive mechanical ventilation (IMV) indicated that the estimated case fatality ratio was 45% (95% CI 39-52%). Among studies where age-specific case fatality ratios were available, pooled estimates ranged from 48% in younger patients (age ≤40) to 84% in older patients (age >80). Case…
October 28, 2020
Residential Context and COVID-19 Mortality among Adults Aged 70 Years and Older in Stockholm: A Population-Based, Observational Study Using Individual-Level Data
Household and neighborhood characteristics associated with COVID-19 mortality among older people (aged ≥70 years) included close exposure to working-age household members, living in a care home, and living in dense neighborhoods. In a population-based cohort of older adults in Stockholm county in Sweden (n= 274,712), close exposure to working-age household members (<66 years) (aHR=1.6), living…
Shorter Incubation Period Is Associated with Severe Disease Progression in Patients with COVID-19
Shorter time between exposure and the development of symptoms was associated with more frequent detection of COVID-19 associated pneumonia. A study of 330 patients hospitalized with laboratory-confirmed COVID-19 in January and February reported that patients with a shorter incubation period (defined as <3 days between the time of exposure and the onset of symptoms) were…
October 27, 2020
Hospitalizations for Chronic Disease and Acute Conditions in the Time of COVID-19
A retrospective study of admissions to 4 hospitals in a New York health system found a substantial decrease in non-COVID-19 hospitalizations across a range of diagnoses during the COVID-19 pandemic, which may have been due in part to patient avoidance of emergency care for fear of COVID-19. Compared to baseline data from 2018 and 2019,…
EXPRESS: Stroke in COVID-19: A Systematic Review and Meta-Analysis
A meta-analysis of 61 studies (108,571 patients) found a 1.4% prevalence of acute cerebrovascular disease (CVD) among patients with COVID-19. The most common manifestation was acute ischemic stroke (87.4%). Patients developing acute CVD were older and more likely to have pre-existing vascular risk factors such as hypertension, diabetes, and coronary artery disease. Nannoni et al….
October 26, 2020
COVID-19–Associated Hospitalizations Among Health Care Personnel — COVID-NET, 13 States, March 1–May 31, 2020
An analysis of COVID-19 hospitalization data from the US found that 6% of adults hospitalized for COVID-19 were health care professionals, of whom 67% were expected to have direct patient contact and 36% were in nursing-related occupations. 90% of health care professionals hospitalized with COVID-19 had at least one underlying condition, of which obesity (73%),…
October 23, 2020
Clinical and Epidemiologic Analysis of COVID-19 Children Cases in Colombia PEDIACOVID
At the national level in Colombia, pediatric patients with more severe COVID-19 were significantly younger than those who experienced mild illness or no symptoms. A retrospective analysis found that the mean age of children who had asymptomatic infection was 9.4 years compared to a mean of 4.9 years among those with severe infection and a…
October 22, 2020
Angiotensin Enzyme Inhibitors and Angiotensin Receptor Blockers as Protective Factors in COVID-19 Mortality: A Retrospective Cohort Study
Odds of mortality were reduced in half among participants taking angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (95% CI = 0.3-0.7) in a retrospective cohort study (n=2,553) after adjusting for underlying conditions, length of stay, age, gender, and ICU admission. A notable confounder was the higher mortality frequency in patients with a history of underlying…
October 21, 2020
Nutritional Risk and Therapy for Severe and Critical COVID-19 Patients: A Multicenter Retrospective Observational Study
Among a cohort of 523 patients hospitalized with COVID-19 from January 2 to February 15, 2020 in China, malnutrition was associated with higher risk of in-hospital death (OR=1.2) and higher risk of poor outcome in the ICU (OR=1.9). After adjustment for age and sex, low BMI and low protein level were also significantly associated with…
October 20, 2020
Synthesis and Systematic Review of Reported Neonatal SARS-CoV-2 Infections
A systematic review and meta-analysis of neonatal case studies of SARS-CoV-2 infection (n=176) defined by at least one positive nasopharyngeal swab or presence of virus-specific IgM found that vertical transmission (mother-to-child) accounted for 30% SARS-CoV-2 infections and environmental exposure accounted for 70% of infections. 64% had abnormal lung imaging, 55% of neonates developed COVID-19, with…
Previous page Next page