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Tag: clinical characteristics
August 25, 2020
Pediatric SARS-CoV-2: Clinical Presentation, Infectivity, and Immune Responses
Preliminary findings from a cohort study of 192 children (mean age 10.2 +/- 7 years) hospitalized with COVID-19 in Massachusetts show that among participants with acute SARS-CoV-2 infection (n=49) viral load in respiratory secretions in the first 2 days of symptoms was significantly higher compared to that of hospitalized adults with severe disease and more…
More than Loss of Taste and Smell: Burning Watering Eyes in Coronavirus Disease 19
A prospective, observational study of 108 non-hospitalized patients with COVID-19 found 69% reported at least one ocular symptom, the most common being burning sensations (n=39), excessive tearing (n=37), and redness (n=28). Rokohl et al. (Aug 20, 2020). More than Loss of Taste and Smell: Burning Watering Eyes in Coronavirus Disease 19 (COVID-19). Clinical Microbiology and…
Prevalence of SARS-CoV-2 Infection in Children Without Symptoms of Coronavirus Disease 2019
• The prevalence of SARS-CoV-2 infection in asymptomatic children (n=33,041) from across the US who were tested for SAR-CoV-2 when presenting for surgical or medical care was strongly correlated with the prevalence of SARS-CoV-2 in the general population in the communities in which the children lived. The authors present a method to estimate the prevalence…
August 24, 2020
COVID-19-Associated Hyperinflammation and Escalation of Patient Care: A Retrospective Longitudinal Cohort Study
Laboratory values indicating hyperinflammation were associated with poor outcomes among patients admitted to hospitals in the UK with COVID-19 (n=269). Patients with hyperinflammation (n=90) had a younger median age (66 vs 71 years) and lower median Charlson Comorbidity Index score (1 vs 2), but a higher proportion of them died during the 28-day follow-up period…
August 21, 2020
Is Blood Type Associated with COVID-19 Severity
• [pre-print, not peer-reviewed] After adjusting for socioeconomic status and comorbidities, Mendy et al. found no association between ABO or Rh blood groups and hospitalization or disease severity among 428 people diagnosed with COVID-19 at the University of Cincinnati’s health system. Mendy et al. (Aug 2020). Is Blood Type Associated with COVID-19 Severity? Pre-print downloaded…
August 20, 2020
COVID-19-Associated Critical Illness-Report of the First 300 Patients Admitted to Intensive Care Units at a New York City Medical Center
• Among 300 patients admitted to ICUs at an academic medical center in New York City from March 10 through April 11, 2020, the majority developed acute respiratory distress syndrome requiring mechanical ventilation (91%) and/or vasopressor-dependent shock (78%). Forty-one percent had acute kidney injury (AKI) present upon admission and 36% subsequently developed AKI. The 30-day…
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