Alliance for Pandemic Preparedness

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Tag: transmission


October 29, 2020

COVID-19 Outbreak at an Overnight Summer School Retreat ― Wisconsin, July–August 2020

Investigation of a SARS-CoV-2 outbreak associated with an overnight high-school retreat suggests a single introduction from a student subsequently infected 76% (116) of attendees. The suspected index case received a negative PCR result 1 week prior to the retreat but experienced symptoms shortly after arrival. The attack rate among susceptible attendees was 91% (116 of…


October 28, 2020

COVID-19 Infections Following Physical School Reopening

[Pre-print, not peer reviewed] A study examining the effect of school re-opening on county-level COVID-19 incidence in Florida reported that counties with in-person instruction experienced a 16% increase in SARS-CoV-2 incidence at day 20 after school reopening among children age 6-13 years (from 11 to 12.8 per 100,000) and an increase of 27% among children…


COVID-19 Infections Following Outdoor Mass Gatherings in Low Incidence Areas Retrospective Cohort Study

[Pre-print, not peer reviewed] Among 20 counties in the US in which mass-gathering rallies associated with presidential campaigns were held (19 outdoor and 1 indoor) during August-September 2020, the COVID-19 incidence increased from 8.6 per 100,000 capita at the time of the gathering to 12.8 per 100,000 capita 15 days after the gathering (average of…


October 27, 2020

Transmission of COVID-19 in the State of Georgia United States Spatiotemporal Variation and Impact of Social Distancing

[Pre-print, not peer reviewed] COVID-19 transmission patterns in the state of Georgia evolved over time, including a contraction of the serial interval between cases and a downward shift in the age of index cases. Data from 4,080 transmission pairs show that the serial interval decreased from 6.0 days in February-April to 4.4 days in June-July….


COVID-19 Outbreak Among a University’s Men’s and Women’s Soccer Teams — Chicago, Illinois, July–August 2020

An outbreak investigation among members of a Chicago university’s men’s and women’s soccer team in August 2020 identified several social gatherings in which transmission could have occurred. The outbreak had a 38% attack proportion (17 out of 45) from the index patient in the men’s soccer team. 18 social gatherings with minimal mask use or…


Characteristics Associated with Household Transmission of SARS-CoV-2 in Ontario Canada

[Pre-print, not peer reviewed] Secondary transmission of SARS-CoV-2 within households was more likely where the index case was male and/or experienced testing delays, in an analysis of address-matched household cohorts of confirmed positive cases in Ontario, Canada. In contrast, being a health worker was associated with lower odds of transmission. Neighborhoods with larger average family…


October 26, 2020

No SARS-CoV-2 Detected in Air Samples (Pollen and Particulate Matter) in Leipzig during the First Spread

Results from a study in Leipzig, Germany during the first wave of SARS-CoV-2 infections did not find pollen to be a carrier for virus particles, nor that bioaerosol samples were infectious. While the authors note that aggregate findings from the study could suggest a correlation between Corylus  pollen species and COVID-19 cases, none of the…


Cell-Based Culture of SARS-CoV-2 Informs Infectivity and Safe de-Isolation Assessments during COVID-19

Basile et al performed SARS-CoV-2 cell-based culture assays to assess infectivity of patients with COVID-19 and compare results to PCR.  They found that viable SARS-CoV-2 was significantly more likely to be isolated from samples collected from inpatients and ICU patients compared with outpatients, and in samples with lower cycle threshold (i.e. higher viral load). The…


A Large National Outbreak of COVID-19 Linked to Air Travel, Ireland, Summer 2020

An analysis of an outbreak of laboratory-confirmed cases of COVID-19 from across Ireland in the summer of 2020 linked the outbreak to an international flight. Onward transmission from 13 passenger cases on the flight resulted in a total of 59 cases in six of eight health regions in Ireland. Attack proportions among contacts were estimated…


Comparison of Upper Respiratory Viral Load Distributions in Asymptomatic and Symptomatic Children Diagnosed with SARS-CoV-2 Infection in Pediatric Hospital Testing Programs

Children with asymptomatic SARS-CoV-2 infection were found to have lower levels of virus in their nasopharynx/oropharynx than children with symptomatic infection, but timing of infection relative to diagnosis likely influenced levels in asymptomatic children. A study assessing Ct values and estimated viral load in children with asymptomatic versus symptomatic infection showed that the median adjusted…



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