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Tag: vaccination
March 10, 2021
Predictors of the Intention to Receive a SARS-CoV-2 Vaccine
A study of 1,054 US adults surveyed in October 2020 indicated factors associated with intention to receive a COVID-19 vaccine were greater perceptions of vulnerability to COVID-19, receipt of a flu vaccine at the time of the study, liberal political orientation, non-Black race, male gender, and a lower preference for natural versus synthetic medications. While…
March 8, 2021
An Increase in Willingness to Vaccinate against COVID-19 in the US between October 2020 and February 2021 Longitudinal Evidence from the Understanding America Study
[Pre-print, not peer-reviewed] Willingness to be vaccinated against COVID-19 increased in the US from October 2020 to February 2021 according to results from a nationally-representative internet-panel of US adults (n = 7,840 participants). Between April and October 2020, there was a sharp decline in willingness to be vaccinated (from 74% to 53%), followed by a…
March 5, 2021
Age-Dependent Immune Response to the BioNtech-Pfizer BNT162b2 COVID-19 Vaccination
[Pre-print, not peer-reviewed] Among 176 participants receiving two doses of the Pfizer-BioNTech vaccine in a cohort study in Germany, participants aged >80 years had lower SARS-CoV-2 specific IgG antibody titers and neutralizing titers compared to participants aged <60 years after each dose. While the IgG titer increase between the first and second dose was larger…
March 3, 2021
Recent Changes in COVID-19 Vaccine Hesitancy among Healthcare Workers
[Pre-print, not peer-reviewed] The willingness of United States Healthcare workers (HCW) to receive an emergency use authorization (EUA)-approved COVID-19 vaccine increased substantially from October, 2020 to December, 2020, according to data from the Healthcare Worker Exposure Response and Outcomes (HERO) Registry. The largest gain in vaccine willingness was observed among physicians, 91% of whom said…
March 2, 2021
Binding and Neutralization Antibody Titers After a Single Vaccine Dose in Health Care Workers Previously Infected With SARS-CoV-2
A single dose of mRNA vaccine (Pfizer or Moderna vaccine) elicited higher antibody and neutralization titers in health care workers (n=59) with previous serology-confirmed SARS-CoV-2 infection compared to healthcare workers who were seronegative at baseline. At 14 days post-vaccination, antibody binding strength to SARS-CoV-2 antigens from participants with both asymptomatic and symptomatic prior infection were…
February 23, 2021
Demographic Benchmarks for Equitable Coverage of the COVID-19 Vaccination Program among Priority Populations
[Pre-print, not peer-reviewed] Essential healthcare workers included in the Phase 1a population defined by the Advisory Committee on Immunization Practices (ACIP) prioritized for vaccination were estimated to have a larger share of women (74%), non-Hispanic Black individuals (18%), and adults aged 25-44 years (41%) compared to the general US population. Phase 1b has a more…
February 22, 2021
Assessment of the Inclusion of Racial/Ethnic Minority, Female, and Older Individuals in Vaccine Clinical Trials
A cross-sectional study of 230 US-based clinical COVID-19 vaccine trials (n = 219,555 participants) found that, compared with the US population, Black or African American (11%), American Indian or Alaska Native (0.4%), Hispanic or Latino (121.6%), and older (age 65+, 12%) individuals were underrepresented, while women (56%) were overrepresented, in trials. Black or African American…
February 16, 2021
Reports of Anaphylaxis After Receipt of MRNA COVID-19 Vaccines in the US—December 14, 2020-January 18, 2021
The CDC identified 66 reports of anaphylaxis from the Vaccine Adverse Event Reporting System (VAERS) during December 14, 2020 to January 18, 2021 (47 cases out of nearly 10 million Pfizer vaccine doses and 19 cases out of nearly 7.6 million Moderna vaccine doses). All cases were treated in healthcare settings, and no deaths from…
February 10, 2021
Patterns of COVID-19 Pandemic Dynamics Following Deployment of a Broad National Immunization Program
[Pre-print, not peer-reviewed] An analysis of data from the Israeli Ministry of Health showed that by February 6, 2021, 45% of the Israeli population had received a first dose of the Pfizer/BioNTech vaccine or had recovered from COVID-19 and 30% had received both doses or recovered form COVID-19. The proportions among those age 60 or…
Understanding Drivers of COVID-19 Vaccine Hesitancy Among Black Community
Findings from focus groups conducted in July and August, 2020 among Black barbershop and salon owners (n=24) living in areas of higher COVID-19 prevalence showed that COVID-19 vaccine hesitancy was high due to mistrust in the medical establishment, concerns regarding the speed of vaccine development, a perception of lack of data on side effects, fear…
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