Result for
Topic: Clinical Characteristics and Health Care Setting
June 25, 2020
Characteristics and Outcomes of COVID-19 Patients in New York City’s Public Hospital System
[Pre-print, not peer reviewed] Marcello et al. reviewed medical records for 22,254 patients tested for SARS-CoV-2 within New York City’s public hospital system, including 13,442 who tested positive, 46% of whom were hospitalized and among whom 28% subsequently died. Chronic diseases including hypertension, diabetes, and cardiovascular disease were common among patients who were hospitalized and died in this large and racially/ethnically diverse sample. Marcello et al. (June 23, 2020). Characteristics and Outcomes of COVID-19…
Characteristics of Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status — United States, January 22–June 7, 2020
Using national COVID-19 surveillance data, Ellington et al. found that among women age 15-44 with SARS-Cov-2 infection, pregnant women were more likely to be hospitalized (RR = 5.41, 95% CI: 5.1-5.6), admitted to ICU (RR = 1.5, 95% CI: 1.1-1.8), and receive mechanical ventilation (RR = 1.7, 95% CI: 1.2-2.4). No association as found with death. The…
June 24, 2020
Risk Factors for 2019 Novel Coronavirus Disease (COVID-19) Patients Progressing to Critical Illness: A Systematic Review and Meta-Analysis
In a meta-analysis of 20 studies, Xu et al. found that gender, advanced age, higher BMI, and comorbidities (diabetes, hypertension, cardiovascular disease, and chronic obstructive pulmonary disease) are associated with higher risk for developing severe COVID-19 disease. In addition, several laboratory measures were also associated with severe disease, notably: high white blood cell count, low…
June 23, 2020
Potential Indirect Effects of the COVID-19 Pandemic on Use of Emergency Departments for Acute Life-Threatening Conditions — United States, January–May 2020
In the 10 weeks following the COVID-19 emergency declaration in the US (March 15–May 23, 2020), emergency department visits reported in the National Syndromic Surveillance Program declined by 23% for heart attacks, 20% for strokes, and 10% for hyperglycemic crisis compared with the previous 10-week period. The authors report that this system captures an estimated 73% of emergency department visits nationwide. The authors conclude that there is a potential…
Decrease in Acute Coronary Syndrome Presentations during the COVID-19 Pandemic in Upstate New York
A multi-center study found admissions for acute coronary syndrome among COVID-19 negative patients dropped by 41% during March/April 2020 (n=67), compared with the same period in 2019 (n=113). A greater proportion of patients with non-ST elevation myocardial infarction presented >24 hours after onset of symptoms in 2020 than in 2019 (36% vs. 27%, p=0.033). The authors conclude that if this decline is due to…
Outcomes among HIV-Positive Patients Hospitalized with COVID-19
A retrospective cohort study that matched 21 HIV-positive COVID-19 patients (median CD4 count 298/uL, <200/uL for 6 patients; all on HAART) to 42 HIV-negative COVID-19 patients hospitalized at New York University Langone Health found those with HIV co-infection had a non-significantly higher risk of changes on chest CT (91% vs 64%), ICU admission (29% vs 17%), mechanical ventilation (24% vs 12%), death…
June 22, 2020
Relationship between ABO Blood Group Distribution and Clinical Characteristics in Patients with COVID-19
Wu et al. explored ABO blood group distribution and clinical characteristics in 187 patients with COVID-19 compared to 1,991 controls at the First Hospital of Changsha in China. Data showed that patients with blood group A had an increased risk for COVID-19 (OR=1.54, 95%CI 1.12, 2.10), whereas blood group O was associated with a decreased risk (OR=0.65, 95%CI 0.46, 0.93). Wu…
Identification and Validation of a Novel Clinical Signature to Predict the Prognosis in Confirmed COVID-19 Patients
Wu et al. constructed a prognostic signature for COVID-19 composed of five indicators (neutrophil count, lymphocyte count, procalcitonin, older age, and C-reactive protein) among 270 patients with confirmed COVID-19. They showed that the combined predictive ability of the signature surpassed the use of each of the five indicators alone and concluded that it could be used as a risk assessment for closely monitoring patients. Wu et al….
Variation in Ventilator Allocation Guidelines by US State During the Coronavirus Disease 2019 Pandemic
Piscitello et al. reviewed publicly available guidelines about ventilator allocation for all states and reported that only 26 US states provided adult guidelines and 14 states provided pediatric guidelines. Guidelines differed in their prioritization criteria, with use of the Sequential Organ Failure Assessment score in the initial rank of adult patients in 15 state guidelines (58%) and assessment of limited life…
June 19, 2020
Prevalence of Taste and Smell Dysfunction in Coronavirus Disease 2019
A retrospective telephone survey of patients diagnosed with COVID-19 during March 5-23, 2020 (n=204) found that 57% reported reduction of taste and/or smell prior to diagnosis and that 40% reported reduction of both taste and smell prior to diagnosis. 55% reported taste reduction and 41% reported smell reduction. Nasal obstruction was rare among patients with…
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