Result for
Topic: Clinical Characteristics and Health Care Setting
June 11, 2020
Anesthesiologists’ and Intensive Care Providers’ Exposure to COVID-19 Infection in a New York City Academic Center: A Prospective Cohort Study Assessing Symptoms and COVID-19 Antibody Testing
Morcuende et al. assessed the incidence of COVID-19-like symptoms and presence of SARS-CoV-2 antibodies among 105 anesthesiologists and affiliated intensive care providers in a large academic hospital in New York City. 58% (61/105) of respondents reporting at least one work-related exposure, of whom only 16 (26%) had post-exposure COVID-19-like symptoms. SARS-CoV-2 was detected in 12% respondents (11/91) with no difference between those who did…
June 8, 2020
Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain
Severe adverse maternal outcomes occurred in 9/82 (11%) pregnant women who tested positive for SARS-CoV-2 in a Spanish cohort. Four of the 9 had mild COVID-19 symptoms and 5/9 had severe symptoms. Women who delivered by cesarean sections (necessitated by COVID-19 symptoms in 100% of those with severe symptoms and 10% of those with mild symptoms) were more likely to require ICU admission and…
Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2
Whittaker et al. compared the features of pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 infection (PIMS-TS) to that of Kawasaki Disease (KD) and KD shock syndrome. Of 58 PIMS-TS patients, 78% had evidence of current or prior SARS-CoV-2 infection. Fifty percent developed shock, 22% met the definition for KD, and 14% developed coronary artery dilatation or aneurysm. Compared with other cases of KD and KD…
Cardiovascular Complications in COVID-19: A Systematic Review and Meta-Analysis
A systematic review and meta-analysis found that the incidence of cardiovascular complications among patients with COVID-19 was highest for heart failure, myocardial injury, and cardiac arrhythmias. Incidence of myocardial injury was higher in older age groups and groups with a higher prevalence of pre-existing hypertension, but did not differ substantially between those with and without pre-existing cardiovascular disease. Kunutsor and Laukkanen. (June 3, 2020). Cardiovascular Complications in COVID-19: A…
June 5, 2020
Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory Failure
A meta-analysis of randomized trials found that among patients with acute hypoxemic respiratory failure, treatment with helmet or facemask non–invasive ventilation was associated with a lower risk of all-cause mortality and intubation compared to standard oxygen therapy alone. Ferreyro et al. (June 4, 2020). Association of Noninvasive Oxygenation Strategies With All-Cause Mortality in Adults With Acute Hypoxemic Respiratory Failure. JAMA. https://doi.org/10.1001/jama.2020.9524
Correlation Between N95 Extended Use and Reuse and Fit Failure in an Emergency Department
Over one third of healthcare workers who had been fit tested for an N95 respirator in the last 1-2 years failed repeat fit testing. Increased number of shifts worn, increased donnings/doffings, and increased hours worn were all associated with a greater likelihood of fit test failure. Degesys et al. (June 4, 2020). Correlation Between N95 Extended Use and Reuse and Fit Failure in an Emergency Department. JAMA. https://doi.org/10.1001/jama.2020.9843
Admissions to Veterans Affairs Hospitals for Emergency Conditions During the COVID-19 Pandemic
Among a pre-established cohort, the number of patients admitted to Veterans Affairs (VA) inpatient facilities for 6 common emergency conditions declined 41% between March 11 and April 21, 2020 compared with the previous 6 weeks, with no similar decline in 2019. The authors conclude that a decrease of this size likely reflects avoidance of hospitals rather than decreased incidence due to declines…
Prevalence of COVID-19 in Out-of-Hospital Cardiac Arrest: Implications for Bystander CPR
Out of 537 out-of-hospital cardiac arrests in Seattle and King County from February 26-April 15, 2020, COVID-19 (laboratory-confirmed or COVID-19 like illness) was diagnosed in 5% of cases that occurred in homes, 11% of cases that occurred in nursing homes, and in no cases that occurred in public places. The authors conclude that delaying bystander CPR to put on PPE should only be considered if prevalence of COVID-19 is…
A Follow-up Study of Recovered Patients with COVID-19 in Wuhan, China
Thirteen out of 1,673 recovered COVID-19 patients under mandatory 2–week quarantine in Wuhan, China were reported to relapse, characterized by mild symptoms, positive PCR results, and chest CT results consistent with COVID-19. All were hospitalized, but none were admitted to the ICU. The remaining 1,660 did not have COVID-19 symptoms and no lung lesions on CT, but it is not clear if…
Neutralizing Antibodies Responses to SARS-CoV-2 in COVID-19 Inpatients and Convalescent Patients
Among 70 COVID-19 patients and patients who had recovered, all had detectable neutralizing anti-SARS-CoV-2 antibodies by 20 days of symptom onset. The study found that neutralizing antibodies were detected in COVID-19 patients even in the early stages of the disease. Older patients and those with more severe symptoms had higher levels of antibodies. Wang et al. (June 4, 2020). Neutralizing Antibodies Responses to SARS-CoV-2…
Previous page Next page