Result for
Topic: Clinical Characteristics and Health Care Setting
March 2, 2020
The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients
Another study examining the neurological effects of COVID-19 suggests that these may be partially responsible for respiratory failure among patients. Li et al. (Feb 27, 2020). The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients. J Med Virol. https://doi.org/10.1002/jmv.25728
A Case Series of children with 2019 novel coronavirus infection: clinical and epidemiological features
Authors describe a case series of 10 pediatric COVID-19 patients in China. Epidemiologic characteristics of each case, including potential sources of infection, and detailed clinical features are provided. While symptoms were generally mild, prolonged viral shedding was observed in respiratory and fecal samples. Jiehao et al. (Feb 28, 2020) A Case Series of children with…
Effects of “Fangcang, Huoshenshan, and Leishenshan” Makeshift Hospitals and Temperature on the Mortality of COVID-19
The establishment of makeshift hospitals and rising ambient temperatures appear associated with improved survival among COVID-19 patients in Hubei. Cai et al. (Feb 29, 2020). Effects of “Fangcang, Huoshenshan, and Leishenshan” Makeshift Hospitals and Temperature on the Mortality of COVID-19. Pre-print downloaded Feb 29 from https://doi.org/10.1101/2020.02.26.20028472
Heart injury signs are associated with higher and earlier mortality in coronavirus disease 2019 (COVID-19)
COVID-19 patients who present with signs of heart injury during the course of their illness may be at higher risk of death than other patients and should be managed carefully. Wu et al. (Feb 29, 2020). Heart injury signs are associated with higher and earlier mortality in coronavirus disease 2019 (COVID-19). Pre-print downloaded Feb 29…
Clinical characteristics of 36 non-survivors with COVID-19 in Wuhan, China
A case series of 36 COVID-19 fatalities yields similar findings to prior research indicating that males with comorbidities are commonly among those who die of the disease. Median time from symptom onset to acute respiratory distress syndrome among these deaths was 11 days, while gradually decreasing lymphocytes and increased inflammation biomarkers were also common. Huang…
Evaluation of the clinical characteristics of suspected or confirmed cases of COVID-19 during home care with isolation: A new retrospective analysis based on O2O
48 confirmed and suspected COVID-19 patients who underwent home isolation without hospitalization in China were monitored via an online platform for symptoms. The authors conclude that frequent laboratory samples and physical examination are not necessary for monitoring patients with mild symptoms. Xu et al. (Feb 29, 2020). Evaluation of the clinical characteristics of suspected or…
February 28, 2020
Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity
Chen et al analyzed virus presence using RT-PCR in blood and pharyngeal and anal swabs. They report that the presence of viral RNA in the blood and anal swab is positively correlated with the severe disease stage. They recommend that early monitoring of virus RNA in blood and the digestive tract on top of the…
Negative Nasopharyngeal and Oropharyngeal Swab Does Not Rule Out COVID-19
This case report describes a 28 year old patient diagnosed with pneumonia who initially tested negative for COVID-19 on nasopharyngeal and oropharyngeal (NP/OP) samples. The patient tested positive for SARS-CoV-2 by RT-PCR on broncho alveolar lavage (BAL) fluid on day 8 of hospitalization. This case highlights the importance of clinical suspicion in the epidemiologically-matched patients…
A Systematic Review of Lopinavir Therapy for SARS Coronavirus and MERS Coronavirus–A Possible Reference for Coronavirus Disease-19 Treatment Option
In absence of FDA-approved antiviral therapies for COVID-19, Yao et al reviewed efficacy of Lopinavir (LPV), an agent used during SARS and MERS epidemic, to clarify its potential for use in patients with COVID-19. Currently a combination of LPV/r is a recommended treatment in China. They reported on two reviews; one with success on limited…
Development and Clinical Application of A Rapid IgM-IgG Combined Antibody Test for SARS-CoV-2 Infection Diagnosis. Journal of Medical Virology
Li et al developed a rapid and simple point-of-care lateral flow immunoassay to simultaneously detect IgM and IgG antibodies within 15 minutes from human blood, plasma, or serum collected at different stages of infection. Overall sensitivity of the combined test was 88.7% and specificity was 90.6% and had better utility and sensitivity than separate IgM…
Previous page Next page