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Topic: Transmission
January 29, 2021
Trends in Outbreak-Associated Cases of COVID-19 — Wisconsin, March–November 2020
COVID-19 cases linked to outbreaks on college campuses in Wisconsin increased rapidly in August 2020, and were followed by outbreaks at long-term care facilities, correctional facilities, and colleges/universities. From May 13–September 2, long-term care facilities (2,850 cases; 21%) and manufacturing or food processing facilities (2,672 cases; 20%) accounted for the largest number of outbreak-associated cases,…
January 28, 2021
Quantifying the Transmission Advantage Associated with N501Y Substitution of SARS-CoV-2 in the United Kingdom: An Early Data-Driven Analysis
Using publicly available SARS-CoV-2 sequencing data and COVID-19 surveillance data collected from August to December 2020 in the UK, Zhao et al. reconstructed the variant-specific instantaneous reproduction number, Rt, and estimated that the variant containing the N501Y mutation is 52% more transmissible than the wild-type virus. Zhao et al. (Jan 28, 2021). Quantifying the Transmission…
Resurgence of COVID-19 in Manaus, Brazil, despite High Seroprevalence
Despite a high SARS-CoV-2 seroprevalence of 76% among blood donors in Manaus, Brazil by October 2020, the area experienced a sudden rise in COVID-19 hospitalizations from 552 in December 2020 to 3,431 in January 2021. The authors suggest possible explanations for the resurgence in this setting where seroprevalence was higher than common estimates of the…
January 27, 2021
SARS-CoV-2 Infection and Mitigation Efforts among Office Workers, Washington, DC, USA
Two SARS-CoV-2 outbreaks in April, 2020 were identified among office workers in Washington, DC. The study identified two factors potentially associated with SARS-CoV-2 infection and transmission in the workplace: a significantly higher percentage of seropositive participants lived with someone who had a confirmed positive test result (13%) than those who were seronegative (1%), and more…
January 26, 2021
Implementation and Evolution of Mitigation Measures, Testing, and Contact Tracing in the National Football League, August 9–November 21, 2020
Investigation of a cluster of 41 SARS-CoV-2 infections that occurred within the National Football League in late September 2020 identified at least 7 cases of infection where transmission likely occurred during <15 minutes of cumulative interaction within 6 feet of an infected individual, as confirmed by wearable tracking devices. Interviews revealed that some of these…
January 25, 2021
NERVTAG Note on B.1.1.7 Severity
[Report, not peer-reviewed] The UK New and Emerging Respiratory Virus Advisory Group (NERVTAG) states the B.1.1.7 SARS-CoV-2 variant has quickly become dominant in the UK, and that there is a possibility that infection with this variant is associated with increased risk of death compared to previous strains. NERVTAG cites evidence of increased case fatality from…
Epidemiological Investigation of a COVID-19 Family Cluster Outbreak Transmitted by a 3-Month-Old Infant
Investigation of a SARS-CoV-2 family cluster outbreak in Wuhan, China transmitted by a 3-month-old infant showed an attack rate of 80% (4/5 family members), and fecal tests for SARS-CoV-2 RNA remained positive for 27 days after the infant was discharged from the hospital. The infant was suspected to have been infected while at a swimming…
Seroprevalence and Seroconversions for SARS-CoV-2 Infections in Workers at Bogota Airport, Colombia 2020
A study of workers (n=212) at the Bogata, Colombia airport conducted between June 1 and September 30, 2020 found that the cumulative incidence and seroprevalence of SARS-CoV-2 among workers was 23.6% and 16.0%, respectively. Most cases were asymptomatic (84%), and 61% of participants seroconverted during the study period, with no significant differences in seroconversion between…
Prevalence of SARS-CoV-2 Infection in Children and Their Parents in Southwest Germany
A multicenter, cross-sectional study of SARS-CoV-2 seroprevalence among children aged 1-10 years (n=2,482) in Germany and a corresponding parent (n=2,482) found that between April 22 and May 15 2020, the estimated seroprevalence was low in parents (1.8%) and 3-fold lower in children (0.6%). Only two participants (0.04%) tested positive for SARS-CoV-2 RNA. Among 56 families…
January 22, 2021
A Cross-Sectional Analysis of Demographic and Behavioral Risk Factors of SARS-CoV-2 Antibody Positivity among a Sample of U.S. College Students
[pre-print, not peer-reviewed] Among undergraduate students at a single college in Indiana, fraternity or sorority membership, having multiple romantic partners, knowing someone with COVID-19, drinking alcohol more than 1 day per week, and attending social gatherings with more than 4 people when drinking alcohol increased both the likelihood of seropositivity and self-reported history of SARS-CoV-2….
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