Colin Studholme, PhD

Professor

phone: +1 206 221 7022
email: studholm@uw.edu

Bio

C. Studholme, PhDDr. Studholme’s research is focused on mathematical and computational techniques to study brain anatomy and its change over time, with a particular focus on fetal and premature neonatal brain growth. His research group, the Biomedical Image Computing Group, is working on new techniques to solve the problem of how to produce images of the human fetal head in utero—which is especially challenging because the fetal head is often moving. Dr. Studholme's group uses magnetic resonance imaging (MRI) to solve this problem and provide the first high-resolution 3D images of early human brain growth. As part of this project, his group has developed a 4-dimensional computational map of tissue volume changes and surface shape changes that occur when the human brain surface begins to fold, in a process that will go on to form the complex anatomy of the adult human brain. In recent papers, Dr. Studholme’s team has mapped the points at which the first differences in the left and right sides of the brain emerge in the developing fetus. The team has developed techniques to accurately compare brain anatomy in premature babies to that of normally developing fetuses. In addition to his ongoing research in this area, he will be a co-investigator on the randomized controlled trial of Epo neuroprotection in extremely preterm infants (PENUT Trial), with the specific aim of evaluating brain growth of Epo treated infants as compared to controls.

Dr. Studholme is also Professor of Pediatrics and Bioengineering, and Adjunct Professor of Radiology. He completed his Ph.D. in medical physics and biophysics from the University of London and a postdoctoral fellowship in diagnostic radiology at Yale University. He has served as faculty at the University of California-San Francisco, visiting faculty member in biomedical engineering at the Mayo Clinic and at the Fields Institute of the University of Toronto, and has recently become an associate editor for the journal IEEE Transactions on Medical Imaging.

Publications

PEER REVIEWED MANUSCRIPTS

International Journal Papers

  1. D.L.G. Hill, D.J. Hawkes, T.C.S. Cox, A.J. Strong, W.L. Wong, C.F. Ruff, N. Kitchen, D.G.T. Thomas, J.E. Cross-man, C. Studholme, A.J. Gandhe, S.E.M. Green, G.P. Robinson, Accurate Frameless Registration of MR and CT Images of the Head: Applications in Surgery and Radiotherapy Planning, Radiology, 191, 1994, pp 447-454.
  2. A.J. Gandhe, D.L.G. Hill, C. Studholme, D.J. Hawkes, C.F. Ruff, A.J. Strong, T.C.S. Cox, M.J. Gleeson, Combined and 3D Rendered Multimodal Data for Planning Skull Base Surgery: A Prospective Evaluation, Neurosurgery, vol 35(3), 1994, pp 463-471.
  3. D.J. Hawkes, C.F. Ruff, D.L.G. Hill, C. Studholme, P.J. Edwards, W.L. Wong, A. Padhani, 3 Dimensional Multi-modal Imaging in Image Guided Interventions, Seminars in interventional radiology, 12, 1995, pp 63-74.
  4. C.Studholme, D.L.G.Hill, D.J. Hawkes, Automated 3-D Registration of MR and CT Images of the Head, Medical Image Analysis , Vol. 1(2)., 1996, pp 163-175.
  5. C. Studholme, D.L.G.Hill, D.J. Hawkes, Automated Three-Dimensional Registration of Magnetic Resonance and Positron Emission Tomography Brain Images by Multiresolution Optimisation of Voxel Similarity Measures, Medical Physics, Vol. 24(1), Jan 1997,pp 25-35.
  6. J. West, J.M. Fitzpatrick, M.Y. Wang, B.M. Dawant, C.R. Maurer, R.M. Kessler, R.J. Maciunas, C. Barillot, D. Lemoine, A. Collignon, F. Maes, P. Suetens, D. Vandermeulen, P.A. van den Elsen,S. Napel,T.S. Sumanaweera, B. Harkness, P.F. Hemler, D.L.G. Hill, D.J. Hawkes, C. Studholme, J.B.A Maintz, M.A. Viergever, G. Malandain, X. Pennec, M.E. Noz,G.Q. Maguire, M. Pollack, C.A. Pelizzari, R.A. Robb,D. Hanson, R.P. Woods, Comparison and Evaluation of Retrospective Intermodality Brain Image Registration Techniques, J. Comp. Assist. Tomog. Vol 21(4), 1997, pp 554-566.
  7. J. Wong, C. Studholme, D.J. Hawkes, M.N. Maisey, Evaluation of the Limits of Visual Detection of Image Misregistration in a Brain F18 PET-MRI Study, European Journal of Nuclear Medicine, Vol 24(6), June 1997, pp 642-650.
  8. D.L.G.Hill, C.R.Maurer, C. Studholme, J.M. Fitzpatrick, D.J.Hawkes, Correcting Scaling Errors in Tomographic Images Using a Nine Degree of Freedom Registration Algorithm, J. Comput Assist. Tomogr., Vol 22(2), 1998, pp 317-323.
  9. J.M. Fitzpatrick, D.L.G. Hill, Y. Shyr, J. West, C. Studholme, C.R. Maurer, Visual Assessment of the Accuracy of Retrospective Registration of MR and CT Images of the Brain, IEEE Trans. Med. Imaging , Vol. 17(4), Aug 1998, pp 571-585.
  10. C. Studholme, D.L.G.Hill, D.J. Hawkes, An Overlap Invariant Entropy Measure of 3D Medical Image Alignment, Pattern Recognition, Vol. 32(1), Jan 1999, pp 71-86.
  11. R.A. Avery, S.S. Spencer, C. Studholme, R.Stokking, G. Morano, M. Corsi, J.P. Seibyl, D.D. Spencer, I.G. Zubal, Reproducibility of Serial Peri-Ictal Single Photon Emission Computed Tomography Difference Images in Epilepsy Patients Undergoing Surgical Resection, Eur. J. Nucl. Med.,27(1),2000,pp 50-53.
  12. R.A. Avery, I.G.Zubal, R. Stokking, C. Studholme, M. Corsi, J.P. Seibyl, S.S. Spencer, Decreased cerebral blood flow during seizures with ictal SPECT injections, Epilepsy Research, 2000, 40, pp 53-61.
  13. R.A. Avery, J.S. Francowicz, C. Studholme, C.H. van Dyck, A.F.T. Arnsten, The Alpha-2A-Adrenoreceptor Agonist, Guanfacine, Increases Regional Cerebral Blood Flow in Dorsolateral Prefrontal Cortex of Monkeys Performing a Spatial Working Memory Task, Neuropsychopharmacology, 2000, Vol 23, No 3.
  14. P.J. Lewis, A. Siegel, A.M. Siegel, C. Studholme,J. Sojkova,D.W. Roberts,V.M. Thadani, K.L. Gilbert,T.M. Darcey, P.D. Williamson, “Does Performing Image Registration and Subtraction in Ictal Brain SPECT Help Localize Neocortical Seizures”, J. Nuc. Med., Oct 2000.
  15. I.G. Zubal, R.A. Avery, R. Stokking, C. Studholme, M. Corsi, H. Dey, J.P. Seibyl,S. Spencer, “Ratio-Images Calculated From Interictal Positron Emission Tomography and Single-Photon Emission Computed Tomography for Quantification of the Uncoupling of Brain Metabolism and Perfusion in Epileps”y, Epilepsia, Vol 41, No. 12, pp 1560-1566, 2000.
  16. C. Studholme, T.C. Constable, J.S. Duncan, Non-Rigid Spin Echo MRI Registration Incorporating an Image Distortion Model: Application to Accurate Alignment of fMRI to Conventional MRI, IEEE Trans. Med. Imaging, Vol 19, No 11. Nov 2000.
  17. J.P. Knisely, J.E. Bond, N.J. Yue, C. Studholme, A.C. de Lotbiniere, Image Registration and Calculation of a Biologically Effective dose for Multisession Radiosurgical Treatments. Technical Note: Journal of Neurosurgery, Dec 2000, 93:Suppl 3, pp 208-218.
  18. C. Studholme, E. Novotny, I.G. Zubal, J.S. Duncan, Estimating Tissue Deformation Between Functional Images Induced by Intracranial Electrode Implantation Using Anatomical MRI, NeuroImage, Vol 13(4), pp 561-576, 2001.
  19. R.A. Avery, I.G. Zubal, C. Studholme, J. Slawski, M. Corsi, D.D. Spencer, S.S. Spencer, Interictal 99 Tc-HMPAO SPECT in Temporal Lobe Epilepsy: Relation to Clinical Variables, Epilepsia, 2001, 42(7), pp 869-874.
  20. A. Carpentier, K.R. Pugh, M. Westerveld, C. Studholme, O. Skrinjar, J.L. Thompson, D.D. Spencer, R.T. Constable, Functional MRI of language processing: dependence on input modality and temporal lobe epilepsy. Epilepsia, pp 1241-1254, Oct, 2001.
  21. D.J. Chang, I.G. Zubal, C. Gottschalk, A. Necochea, R. Stokking, C. Studholme, M. Corsi, J. Slawski, S. S.Spencer, H. Blumenfeld, “Comparison of Statistical Parametric Mapping and SPECT Difference Imaging in Patients with Temporal Lobe Epilepsy”, Epilepsia, 2002.
  22. H. Blumenfeld, M. Westerveld, R.B. Ostroff, S.D. Vanderhill, J. Freeman, A. Necochea, P. Uranga, T. Tanhehco, A. Smoth, J.P. Seibyl, R.Stokking, C. Studholme, S.S. Spencer, I.G. Zubal, “Selective Frontal, Parietal and Temporal Network Activation in Generalized Seizures”, Neuroimage 19:1556-1566 2003.
  23. C. Studholme, V. Cardenas, A. Maudsley, M. Weiner, “An Intensity Consistent Filtering Approach to the Analysis of Deformation Tensor Derived Maps of Brain Shape”, NeuroImage, Vol19(4), August 2003, pp 1638-1649.
  24. C. Studholme, V. Cardenas, E. Song, F. Ezekiel, A. Maudsley, M. Weiner, “Accurate Template Based Estimation of Brain MRI Bias Fields with Application to Dementia and Aging”, IEEE Transactions on Medical Imaging, Vol 23(1), Jan 2004.
  25. N.J. Yue, J. P.S. Knisely, C. Studholme, Z. Chen, J. Bond, R. Nath, “A Technique to re-establish dose distributions for previously treated brain cancer patients in external beam radiotherapy”, Medical Dosimetry, Vol 29, No. 1, pp 31-41, 2004.
  26. C.Studholme, V. Cardenas, R. Blumenfeld, N. Schuff, H.J. Rosen, B. Miller, M. Weiner, “A Deformation Tensor Morphometry Study of Semantic Dementia with Quantitative Validation”, NeuroImage, Vol 21, pp 1387-1398, April 2004.
  27. D.J. Meyerhoff, R.Blumenfeld, D.Truran, J. Lindgren, D, Flenniken, V.A. Cardenas, L. Chao, J. Rothlind, C.Studholme, M.W. Weiner. Effects of heavy drinking, binge drinking and family history of alcoholism on regional brain metabolites, Alcoholism: Clinical and Experimental Research., 28(4), pp 650-661, Apr 2004.
  28. Hal Blumenfeld, Kelly A. McNally, Susan D. Vanderhill, A. LeBron Paige, Richard Chung, Kathryn Davis, Andrew D. Norden, Rik Stokking, Colin Studholme, Edward J. Novotny, Jr., I. George Zubal, and Susan S. Spencer. Positive and negative network correlations in temporal lobe epilepsy. Cerebral Cortex, Vol 14(8), 2004, pp892-902.
  29. C.Studholme, V. Cardenas, “A Template Free Approach to Volumetric Spatial Normalisation of Brain Anatomy”, Pattern Recognition Letters, Vol 25(10), Jul 2004, pp. 1191-1202.
  30. V. Cardenas, L.Chow, R. Blumenfeld, E. Song, D. Meyerhoff, M. Weiner, C. Studholme, “Using Automated Morphometry to Detect Associations between ERP latency and structural brain MRI in normal adults” ,Human Brain Mapping, 25, 2005, pp 317-327.
  31. V.A. Cardenas, E.Song, C.Studholme, R.Blumenfeld, D.Truran, D.J. Meyerhoff, M.W. Weiner. “Chronic Active Heavy drinking and family history of problem drinking modulate regional brain tissue volumes”, Psychiatry Research: Neuroimaging, vol 138, pp 115-130, 2005.
  32. C. Drapaca, V. Cardenas, C. Studholme, “Segmentation of Tissue Boundary Evolution from Brain MR Image Sequences using Multi-phase Level Sets”, Computer Vision and Image Understanding, volume 100, 2005, pages 312-329.
  33. S. Gazdzinski, T.C. Durazzo, C. Studholme, E Song, P. Banys, D.J. Meyerhoff, Quantitative brain MRI in alcohol dependence: preliminary evidence for effects of concurrent chronic cigarette smoking on regional brain volumes. Alcohol Clin Exp Res. 2005 Aug;29(8):1484-95.
  34. Colin Studholme, Corina Drapaca, Bistra Iordanova, Valerie Cardenas, “Deformation Based Mapping of Volume Change from Serial Brain MRI in the Presence of Local Tissue Contrast Change”, IEEE Transactions on Medical Imaging, Vol 25(5), pp 626-639, May 2006.
  35. Bistra Iordanova, Daniel Rosenbaum, David Norman, Michael Weiner, Colin Studholme, “MRI study of Neurodegeneration: A Robust Volumetric Parcellation Method of the Frontal Lobe Gyri with Quantitative Validation in Dementia Patients”, AJNR, vol 27, pp 1747-1754, Sep 2006.
  36. A. Maudsley, A. Darkazanli, J.R. Alger, L.O. Hall, N. Schuff, C. Studholme, Y. Yu, A. Ebel, A. Frew, D. Goldgof, Y.Gu, R. Pagare, F. Rousseau, K. Sivasankaren, B.J. Soher, P. Weber, K. Young, X. Zhu, “Comprehensive processing, display and analysis for in vivo MR spectroscopic imaging”, NMR in Biomedicine, June 2006, 19(4), pp 492-503.
  37. A.D. Leow, A.D. Klunder, C.R. Jack, A.W. Toga, A.M. Dale, M.A. Bertstein, P.J. Britson, J.L. Gunter, C.P. Ward, J.L. Whitewell, B. Borowski, A. Fleisher, N.C. Fox, D. Harvery, J. Kornak, N. Schuff, C. Studholme, G.E. Alexander, M.W. Weiner, P.M. Thompson, “Longitudinal Stability of MRI for Mapping Brain Change using Tensor-Based Morphometry”, Neuroimage, June 2006, 31(2) pp 627-640.
  38. F. Rousseau, O. Glenn, B. Iordanova, Cl. Rodriguez, D. Vigneron, J. Barkovich, C. Studholme, Registration Based Approach for Reconstruction of High Resolution In Utero MR Brain Images, Academic Radiology, 13(9), Sept 2006, pp1072-1081.
  39. T. Durazzo, V.A. Cardenas, C. Studholme, M.W. Weiner, D.J. Meyerhoff, Non-treatment-seeking heavy drinkers: Effects of chronic smoking on brain structure. Drug Alcohol Depend. 87, Jan 2007, pp 76-82.
  40. V.A. Cardenas A.L. Boxer, L.L.Chao, M.L. Gorono-Tempini, B.L. Miller, M.Weiner, C. Studholme, “Deformation Morphometry Reveals Brain Atrophy in Frontotemporal Dementia”,Archives of Neurology, 64(6), pages 873-877,June 2007.
  41. V. Cardenas, C. Studholme, S. Gazdzinski, T. Durazzo D. Meyerhoff, ``Deformation Based Morphometry of Brain Volume Changes During Recovery from Alcohol Dependence'', Neuroimage,34(3), 2007, pp 879-887.
  42. Durazzo TC, Rothlind JC, Cardenas VA, Studholme C, Weiner MW, Meyerhoff DJ., “Chronic cigarette smoking and heavy drinking in human immunodeficiency virus: consequences for neurocognition and brain morphology.”, Alcohol. 2007 Nov;41(7):489-501. Epub 2007 Oct 17.
  43. K. Strostrand, E. Rostrup, C. Ryberg, R. Larsen, C. Studholme, H. Baezner, J. Ferro, F. Fazekas, L. Pantoni, D. Inzitari, and G. Waldemar “Sparse Decomposition and Modeling of Anatomical Shape Variation”, IEEE Transactions on Medical Imaging, 26(12), Dec 2007, pp 1625-1635.
  44. C. Rodriguez, Pratik Muhkerjee, D. Vigneron, J. Barkovich, C. Studholme, “A Framework for in-vivo analysis of regional brain folding in premature neonates”, NeuroImage, Neuroimage, vol. 41, no. 2, pp. 462-478, 2008.
  45. Norbert Schuff , Thomas C. Neylan, Sabrina Fox-Bosetti, Maryanne Lenoci, Kristin W. Samuelson, C. Studholme, John Kornak, Charles R. Marmar, Michael Weiner, “Abnormal N-acetylaspartate in hippocampus and anterior cingulate in posttraumatic stress disorder”, Psychiatry Research Neuroimaging, 2008.
  46. Jack CR Jr, Bernstein MA, Fox NC, Thompson P, Alexander G, Harvey D, Borowski B, Britson PJ, L Whitwell J, Ward C, Dale AM, Felmlee JP, Gunter JL, Hill DL, Killiany R, Schuff N, Fox-Bosetti S, Lin C, Studholme C, DeCarli CS, Krueger G, Ward HA, Metzger GJ, Scott KT, Mallozzi R, Blezek D, Levy J, Debbins JP, Fleisher AS, Albert M, Green R, Bartzokis G, Glover G, Mugler J, Weiner MW. The Alzheimer’s Disease Neuroimaging Initiative (ADNI): MRI methods. J Magn Reson Imaging. 2008 Apr;27(4):685-91.
  47. J Blumenfeld, C Studholme, J Carballido-Gamio, D Carpenter, T M. Link, S Majumdar, “Three-dimensional image registration of MR proximal femur images for the analysis of trabecular bone parameters”, Med. Phys., vol. 35, no. 10, pp. 4630-4639, October 2008.
  48. C. Studholme, “Dense Feature Deformation Morphometry: Incorporating DTI Data into Conventional MRI Morphometry”, Medical Image Analysis, Volume 12, Issue 6, December 2008, Pages 742-751 2008.
  49. S. Hadjidemetriou, C. Studholme, S. Mueller, M. W. Weiner, and N. Schuff, "Restoration of MRI data for intensity non-uniformities using local high order intensity statistics," Med. Image Anal., vol. 13, no. 1, pp. 36-48, February 2009.
  50. A. A. Maudsley, C. Domenig, V. Govindaraju, A. Darkazanli, C. Studholme, K. Arheart, and C. Bloomer. “Mapping of brain metabolite distributions by volumetric proton MRSI”. Magn. Reson. Med. vol. 61, no. 3, pp. 548-559, March 2009.
  51. Valerie Cardenas, Linda L Chao, Colin Studholme, Kristine Yaffe, Bruce L Miller, Catherine Madison, Shannon Buckley, Dan Mungas, Norbert Schuff, Michael W Weiner,”Brain atrophy associated with baseline and longitudinal measures of cognition”, Neurobiology of Aging, vol. 32, no. 4, pp. 572-580, April 2011.
  52. V.A. Cardenas, D.J. Meyerhoff, C. Studholme, J. Kornak, J. Rothlind, H. Lampiris, J. Neuhaus, R.M. Grant, M.D, L.L. Chao, D. Truran, B.A., and M.W. Weiner,M.D. Evidence for Ongoing brain injury in HIV+ patients treated with antiretroviral therapy. Journal of Neurovirology, vol. 15, no. 4, pp. 324-333, June 2009.
  53. N. Schuff, S. Matsumoto, J. Kmiecik, C. Studholme, A.T.Du, F. Ezekiel,B.L. Miller, J.H. Kramer, W.J. Jagust, H.C. Chui, M.W.Weiner. Cerebral Blood Flow in Ischemic Vascular Dementia and Alzheimer's Disease By Arterial Spin Labeling MRI. Alzheimer's & Dementia, pp454-462 Vol 5, Issue 6, Nov 2009
  54. Schneider MM, Berman JI, Baumer FM, Glass HC, Jeng S, Jeremy RJ, Esch M, Biran V, Barkovich AJ, Studholme C, Xu D, and Glenn OA. Normative ADC values in the developing fetal brain. American Journal of Neuroradiology, In Press, Oct 2009.
  55. K.Young, V. Govindaraju, K. Sharma, C.Studholme, A.A Maudsley, N. Schuff, “Multivariate Statistical Mapping of Spectroscopic Imaging Data ”, Magn. Reson. Med., vol. 63, no. 1, pp. 20-24, January 2010.
  56. K.Kio, P. Habas, O. Glenn, A.J. Barkovich, C.Studholme, “Intersection Based Motion Correction of Multi-Slice MRI for 3D in utero Fetal Brain Image Formation”, IEEE Trans. Med. Imaging, vol. 29, no. 1, pp. 146-158, January 2010.
  57. P. A. Habas, K. Kim, F. Rousseau, O. A. Glenn, A. J. Barkovich, C. Studholme, "Atlas-based segmentation of developing tissues in the human brain with quantitative validation in young fetuses," Hum. Brain Mapping, 31: 1348-1358.
  58. B. Caldairoua, N. Passat, P. A. Habas, C. Studholme, and F. Rousseau, "A non-local fuzzy segmentation method: application to brain MRI," Pattern Recognit., vol. 44, no. 9, pp. 1916-1927, September 2011.
  59. P. A. Habas, K. Kim, J. M. Corbett-Detig, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, A spatiotemporal atlas of MR intensity, tissue probability and shape of the fetal brain with application to segmentation," Neuroimage 53 (2), 460–470.
  60. E. W.Y. Tam, S. P. Miller, C. Studholme, V. Chau, D. Glidden, K. J. Poskitt, D. M. Ferriero, A. James Barkovich, Differential Effects of Intraventricular Hemorrhage and White Matter Injury on Preterm Cerebellar Growth, J. Pediatrics, J. Pediatr., vol. 158, no. 3, pp. 366-371, March 2011.
  61. J. M. Corbett-Detig, P. A. Habas, J. A. Scott, K. Kim, V. Rajagopalan, P. S. McQuillen, A. J. Barkovich, O. A. Glenn, and C. Studholme, "3D global and regional patterns of human fetal subplate growth determined in utero," Brain Struct. Funct., vol. 215, no. 3-4, pp. 255-263, January 2011.
  62. V. Rajagopalan, J. A. Scott, P. A. Habas, J. M. Corbett-Detig, K. Kim, F. Rousseau, A. J. Barkovich, O. A. Glenn, and C. Studholme, "Local tissue growth patterns underlying normal fetal human brain gyrification quantified in utero," J. Neurosci., vol. 31, no. 8, pp. 2878-2887, February 2011.
  63. F. D. Jacob, P. A. Habas, K. Kim, J. M. Corbett-Detig, D. Xu, C. Studholme, and O. A. Glenn, "Fetal hippocampal development: analysis by magnetic resonance imaging volumetry," Pediatr. Res., vol. 69, no. 5, pp. 425-429, May 2011.
  64. J. A. Scott, P. A. Habas, K. Kim, V. Rajagopalan, K. S. Hamzelou, J. M. Corbett-Detig, A. J. Barkovich, O. A. Glenn, and C. Studholme, "Growth trajectories of the human fetal brain tissues estimated from 3D reconstructed in utero MRI," Int. J. Dev. Neurosci., vol. 29, no. 5, pp. 529-536, August 2011.
  65. C. Studholme, "Mapping fetal brain development in utero using MRI: the big bang of brain mapping," Annu. Rev. Biomed. Eng., vol. 13, no. 1, pp. 345-368, August 2011.
  66. B. Caldairou, N. Passat, P. A. Habas, C. Studholme, and F. Rousseau, "A non-local fuzzy segmentation method: application to brain MRI," Pattern Recognit., vol. 44, no. 9, pp. 1916-1927, September 2011.
  67. P. A. Habas, J. A. Scott, A. Roosta, V. Rajagopalan, K. Kim, F. Rousseau, A. J. Barkovich, O. A. Glenn, and C. Studholme, "Early folding patterns and asymmetries of the normal human brain detected from in utero MRI," Cereb. Cortex, in press.
  68. E. Oubel, M. Koob, C. Studholme, J.-L. Dietemann, and F. Rousseau, "Reconstruction of scattered data in fetal diffusion MRI," Med. Image Anal. vol. 16, no. 1, pp. 28-37, January 2012.
  69. K. Kim, P. A. Habas, V. Rajagopalan, J. A. Scott, J. M. Corbett-Detig, F. Rousseau , A. J. Barkovich, O A. Glenn, and C. Studholme, "Bias field inconsistency correction of motion-scattered multislice MRI for improved 3D image reconstruction," IEEE Trans. Med. Imaging, in press.
  70. F. Rousseau, P. A. Habas, and C. Studholme, "A supervised patch-based approach for human brain labeling," IEEE Trans. Med. Imaging, vol. 30, no. 10, pp. 1852-1862, October 2011.J.
  71. J. A. Scott, K. S. Hamzelou, V. Rajagopalan, P. A. Habas, K. Kim, A. J. Barkovich, O. A. Glenn, and C. Studholme, " 3D morphometric analysis of human fetal cerebellar development, " Cerebellum, 11(3):761-70, Sep 2012
  72. V. Rajagopalan, J. Scott, P.A. Habas, K. Kim, F. Rousseau, A.J. Barkovich, O.A. Glenn, C. Studholme, "Mapping directionality specific volume changes using tensor based morphometry: An application to the study of gryrogenesis and lateralization of the human fetal brain," NeuroImage, 1;63(2):947-58. Nov 2012
  73. J. Scott, V. Rajagopalan, P.A. Habas, K. Kim, A.J. Barkovich, O.A. Glenn, C. Studholme, "Volumetric and surface-based 3D MRI analyses of fetal isolated mild ventriculomegaly, " Brain Struct Funct, 2012.
  74. Francois Rousseau, Estanislao Oubel, Julien Pontabry, Marc Schweitzer, Colin Studholme, Meriam Koob, Jean-Louis Dietemann, "BTK: An open-source toolkit for fetal brain MR image processing, " Comput Methods Programs Biomed. 109(1):65-73 Jan 2013.
  75. Atman Desai, Kimon Bekelis, Vijay M. Thadani, David W. Roberts1, Barbara C. Jobst, Ann-Christine Duhaime, Karen Gilbert, Terrance M. Darcey, Colin Studholme, Alan Siegel, " Interictal PET and ictal subtraction SPECT: Sensitivity in the detection of seizure foci in patients with medically intractable epilepsy ", Epilepsia;54(2):341-50 Feb 2013.
  76. Moriah E. Thomason, Maya T. Dassanayake, Stephen Shen, Yashwanth Katkuri, Mitchell Alexis, Amy L. Anderson Lami Yeo, Swati Mody, Edgar Hernandez-Andrade Sonia S. Hassan, Colin Studholme, Jeong-Won Jeong, Roberto Romero, " Cross-Hemispheric Functional Connectivity in the Human Fetal Brain. " Sci Transl Med 5, 173, 2013
  77. J. Pontabry, F. Rousseau , E. Oubel, C. Studholme, M. Koob, J.-L. Dietemann,Probabilistic, " Tractography Using Q-Ball Imaging and Particle Filtering: Application to Adult and in-utero Fetal Brain Studies ", Medical Image Analysis, Volume 17, Issue 3, Pages 297–310, April 2013.

Peer Reviewed Full Conference Papers Published in Book Form:

  1. L.D. Griffin, A.C.F. Colchester, S.A. Roll, C. Studholme, Hierarchical Segmentation Satisfying constraints, Proceedings of the British Machine Vision Conference, BMVA Press, UK, 1994, vol 1, pages 135-144.
  2. D.Hill, C. Studholme, D. Hawkes, “Voxel Similarity Measures for Automated Image Registration”, Proceedings of Medical Imaging 1994, San Diego, SPIE Press, Vol 2359, pp 205-216.
  3. J. West, J. Fitzpatrick, M. Wang, B. Dawant, C. Maurer, R. Keesler, R. Maciunas, C. Barillot, D. Lemoine, A. Collignon, F. Maes, P. Suetens, D. Vandermeulen, P.van den Elsen, P. Hemler, S. Napel, T. Sumanaweera, B. Harkness, D. Hill, C. Studholme, G. Malandain, X. Pennec, M. Noz, G. Maguire, M. Pollack, C. Pelizzari, R. Robb, D. Hanson, R. Woods. “Comparison and evaluation of retrospective intermodality image registration techniques”, Proceedings of Medical Imaging 1996, San Diego, SPIE Press, Vol 2710, pp332-347.
  4. C. Studholme, D.L.G.Hill, D.J. Hawkes, Multiresolution Voxel Similarity Measures for MR-PET Registration, Proceedings of Information Processing in Medical Imaging, Brest, France, June 1995, Eds. Y.Bizais, Christian Barillot, pp 287-298, Kluwer Academic Publishers, ISBN 0-7923-3593-7.
  5. C.Studholme, D.L.G.Hill, J.Wong, M.N.Maisey, D.J.Hawkes, Registration Measures for Automated 3D Alignment of PET and Intensity Distorted MR Images, Proceedings in Image Fusion and Shape Variability Techniques, Leeds, July 1996, Eds. K.V. Mardia, C.A. Gill, I.L. Dryden, pp 186-193, Leeds University Press.
  6. C. Studholme, J.A. Little, G. P. Penny, D.L.G. Hill, D.J. Hawkes, Automated Multi Modality Registration Using the Full Affine Transformation: Application to MR and CT Guided Skull Base Surgery, Proceedings of Visualisation in Biomedical Computing, Hamburg, Germany, Sept. 1996, Eds. Karl Heinz Hohne and Ron Kikinis, pp 601-606, Springer, Lecture Notes in Computer Science, ISBN 3-540-61649-7.
  7. C. Studholme, D.L.G.Hill, D.J.Hawkes, Incorporating Connected Region Labeling into Automated Image Registration Using Mutual Information, Proceedings of the IEEE workshop on Mathematical Methods in Biomedical Image Analysis, San Francisco Ca., June 1996, pp 23-31, IEEE Computer Society Press.
  8. D. Ruckert, C. Hayes, C. Studholme, M. Leach D.J. Hawkes, Non-rigid Registration of Breast MR images using Mutual Information, Proceedings of MICCAI, Cambridge MA, USA, Oct 1998, pp 1144-1152,W. M. Wells A. Colchester, S. Delp., Springer-Verlag.
  9. C. Studholme, D.L.G. Hill, D.J.Hawkes ,A Normalised Entropy Measure of 3D Medical Image Alignment, Proceedings of Medical Imaging 1998,San Diego, SPIE Press. pp. 132-143.
  10. 10. M. Holden, ERE Denton, J.M. Jarosz, C. Studholme, D.L.G. Hill, D.J.Hawkes, Detecting small Anatomical Change with 3D serial MR subtraction images, Proceedings of Medical Imaging 1999,San Diego, SPIE Press. Vol 3661, pp 44-55.
  11. C. Studholme, R. Todd Constable, James S. Duncan, Incorporating an Image Distortion Model in Non-Rigid Alignment of EPI with Conventional MRI, Proceedings of Information Processing in Medical Imaging, Hungary, June 1999, pp 454-459, Springer-Verlag, ISBN 3-540-66167-0.
  12. C. Studholme, V. Cardenas, and M. Weiner. Multi scale image and multi scale deformation of brain anatomy for building average brain atlases. In Proceedings SPIE Medical Imaging, vol. 4322-60, pages 557–568, 2001.
  13. C. Studholme, V. Cardenas, N. Schuff, H. Rosen, B. Miller, and M. Weiner. Detecting spatially consistent structural differences in Alzheimer’s and Fronto temporal dementia using deformation morphometry. In Proceedings of 4thInternational Conference on Medical Image Computing and Computer Assisted Interventions, 2001, pages 41–48, 2001, Springer-Verlag, ISBN 3-540-42697-3.
  14. C. Studholme, V. Cardenas, A.Maudsley, M. Weiner, “An Intensity Consistent Approach to the Cross Sectional Analysis of Deformation Tensor Derived Maps of Brain Shape”, In Proceedings of 5th International Conference on Medical Image Computing and Computer Assisted Interventions, 2002, pages 492-499, 2002, Springer-Verlag.
  15. C. Studholme, Simultaneous Population Based Image Alignment For Template Free Spatial Normalisation of Brain Anatomy, Proceedings of the 2nd International Workshop on Biomedical Image Registration, June 23-24 2003, Eds J. Gee, J. Maintz, M. Vannier, Springer Verlag LLNCS 2717, pages 81-90, 2003.
  16. C. Drapaca, V. Cardenas, C. Studholme, Robust Space-Time Extraction of Ventricular Surface Evolution using Multiphase Level Sets, Proceedings of SPIE Medical Imaging 2004, vol 5370, pages 538-548, 2004.
  17. V. Cardenas, C. Studholme, Co-analysis of maps of Atrophy Rate and Atrophy State in Neuodegeneration, Proc. Medical Image Computing and Computer Assistant Interventions 2004, Eds Barillot, Haynor, Hellier, Springer Verlag LLNCS 3217, Vol 2, Pages 680-687, 2004.
  18. F. Rousseau, A. Maudsley, A. Ebel, A. Darkazanil, P. Weber, K. Sivasankaran, Y. Yu, C. Studholme, ”Evaluation of sub-voxel registration accuracy between MRI and 3D MR spectroscopy of the brain”, Proceedings of SPIE Medical Imaging: Image Processing 2005, vol 5747, pp 1213-1221.
  19. C. Studholme, C. Drapaca, V. Cardenas, “Intensity Robust Viscous Fluid Deformation Based Morphometry Using Regionally Adapted Mutual Information”, Proceedings of the 27th Annual Conference of the IEEE Engineering in Medicine and Biology Society, Sept 1-4, 2005.
  20. F. Rousseau, O. Glenn, B. Iordanova, C. Rodriguez-Carranza, D. Vigneron, J. Barkovich , C. Studholme,” Reconstructing High Resolution In Vivo Fetal {MR} Brain Images”, Proceedings of Medical Image Computing and Computer Assisted Interventions 2005, Eds. J. Duncan and G.Gerig, pp 548-555, Springer Verlag, LNCS 3749, 2005.
  21. C. Rodriguez-Carranza, F. Rousseau, B. Iordanova, D. Vigneron, P. Mukerjee, A.J. Barkovich, C. Studholme, “An iso-surface folding analysis method applied to premature neonatal brain development”, Proceedings of SPIE medical imaging, Image Processing 2006, vol 6144, pages 1K1-1K11, San Diego, U.S.A.
  22. C. Studholme, “Incorporating DTI data as a Constraint in Deformation Tensor Morphometry Between T1 MR Images”, Proceedings of Information Processing in Medical Imaging 2007, (Ed N. Karssemeijer and B. Lelieveldt) pp 223-232, Springer-Verlag LNCS 4584.
  23. C. Studholme, V. Cardendas, “Population Based Analysis of Directional Information in Serial Deformation Tensor Morphometry”. Proceedings of Medical Image Computing and Computer Assisted Interventions 2007, pp LNCS, vol. 4792, pp. 311-318, November 2007
  24. K. Sjostrand, V. A. Cardenas, R. Larsen, and C. Studholme, "A generalization of voxel-wise procedures for high-dimensional statistical inference using ridge regression," in Medical Imaging 2008: Image Processing, Proc. SPIE, vol. 6914, pp. 69140A, February 2008.
  25. J. Blumenfeld, C. Studholme, J. Carballido-Gamio, T. M. Link, and S. Majumdar, "Three-dimensional image registration of MR proximal femur images for the analysis of trabecular bone parameters," in Medical Imaging 2008: Image Processing, Proc. SPIE, vol. 6914, pp. 69140G, February 2008.
  26. K. Kim, M. F. Hansen, P. A. Habas, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Intersection-based registration of slice stacks to form 3D images of the human fetal brain," in Proc. 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, pp. 1167-1170, May 2008.
  27. P. A. Habas, K. Kim, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Atlas-based segmentation of the germinal matrix from in utero clinical MRI of the fetal brain," in Medical Image Computing and Computer-Assisted Intervention, LNCS, vol. 5241, part I, pp. 351-358, September 2008.
  28. Piotr A. Habas, Kio Kim, Dharshan Chandramohan, Francois Rousseau, Orit A. Glenn, Colin Studholme, “Statistical model of laminar structure for atlas-based segmentation of the fetal brain from in utero MR images”, Proc. SPIE, vol., pp February 2009.
  29. Piotr A. Habas, Kio Kim, Dharshan Chandramohan, Francois Rousseau, Orit A. Glenn, Colin Studholme, “A spatio-temporal atlas of the human fetal brain with application to tissue segmentation”, ," in Medical Image Computing and Computer-Assisted Intervention, LNCS, September 2009
  30. K. Kim, P. A. Habas, F. Rousseau, O. A. Glenn, A. J. Barkovich and C. Studholme, "Reconstruction of a geometrically correct diffusion tensor image of a moving human fetal brain," in Medical Imaging 2010: Image Processing, In Press.
  31. F. Rousseau, K. Kim, and C. Studholme, "A groupwise super-resolution approach: application to brain MRI," in Proc. IEEE International Symposium on Biomedical Imaging: From Nano to Macro, April 2010.
  32. K. Kim, P. A. Habas, V. Rajagopalan, J. A. Scott, J. M. Corbett-Detig, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Non-iterative relative bias correction for 3D reconstruction of in utero fetal brain MR imaging," in Proc. 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, September 2010.
  33. V. Rajagopalan, J. A. Scott, P. A. Habas, K. Kim, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Measures for characterizing directionality specific volume changes in TBM of brain growth," in Medical Image Computing and Computer Assisted Intervention, September 2010.
  34. Estanislao Oubel, Meriam Koob, Colin Studholme, Jean-Luis Dietemann, François Rousseau, “Reconstruction of Scattered Data in Fetal Diffusion MRI”, in Medical Image Computing and Computer Assisted Intervention, September 2010.
  35. François Rousseau, Kio Kim, Colin Studholme, MeriamKoob, Jean-Louis Dietemann, “On Super-Resolution for Fetal Brain MRI” in Medical Image Computing and Computer Assisted Intervention, September 2010.
  36. B. Caldairou, N. Passat, P. A. Habas, C. Studholme, M. Koob, J.-L. Dietemann, and F. Rousseau, "Cortex segmentation in reconstructed fetal MRI by using structural constraints," in Proc. International Conference on Computer Analysis of Images and Patterns, August 2011.
  37. F. Rousseau, P. A. Habas, and C. Studholme, "Human brain labeling using image similarities," in Proc. IEEE Computer Vision and Pattern Recognition, June 2011.
  38. B. Caldairou, N. Passat, P. A. Habas, C. Studholme, M. Koob, J.-L. Dietemann, and F. Rousseau, "Segmentation of the cortex in fetal MRI using a topological model," in Proc. IEEE International Symposium on Biomedical Imaging: From Nano to Macro, March-April 2011.
  39. P. A. Habas, V. Rajagopalan, J. A. Scott, K. Kim, A. Roosta, F. Rousseau, A. J. Barkovich, O. A. Glenn, and C. Studholme, "Detection and mapping of delays in early cortical folding derived from in utero MRI," in Medical Imaging 2011: Image Processing, Proc. SPIE, vol. 7962, 7692O0, February 2011.
  40. K. Kim, P. A. Habas, V. Rajagopalan, J. A. Scott, F. Rousseau, A. J. Barkovich, O. A. Glenn, and C. Studholme, "SLIMMER: SLice MRI Motion Estimation and Reconstruction tool for studies of fetal anatomy," in Medical Imaging 2011: Image Processing, Proc. SPIE, vol. 7962, 79624D, February 2011.

Shorter ABSTRACTS

  1. D.L.G. Hill, D.J. Hawkes, C. Studholme, P.E. Summers, M.G. Taylor, Accurate Registration and Transformation of Temporal Image Sequences, Proc. Soc. Magn. Resn. 2nd Annual Meeting, Aug 2-12 1994, pp 820.
  2. C. Studholme, P.Summers, D.L.G. Hill, D.J. Hawkes, An Information Theory Approach to the Alignment of Images Containing Measurement Inhomogeneity: Application to MR Surface Coil Angiography of the Brain, Proceedings of Medical Image Understanding and Analysis, Oxford, July 1997.
  3. C. Studholme, R. Todd Constable, James S. Duncan, Constraining Non-Rigid Registration of EPI to Conventional MRI using an MR Distortion Model, Proc. International Soc. Magn. Resn. in Med. Annual Meeting, May 1999.
  4. R.T. Constable A.C. Carpentier K.R. Pugh C. Studholme O. Skrinjar D.D. Spencer ,fMRI Mapping of Language Processing: Comparison with Wada Testing and Cortical Stimulation, Proceedings of ISMRM 2000, Denver, Col., USA.,2000, pp 323.
  5. T. Constable C. Studholme D.D. Spencer, Rapid High SNR EPI Based Field Maps without the Need for Phase Unwrapping, Proceedings of ISMRM 2000, Denver, Col., USA.,2000, pp 1521.
  6. O. Skrinjar A. Carpentier T. Constable C. Studholme J.S. Duncan, A Platform for Visualisation of Anatomical, Functional and Sub-dural Cortical Stimulation Data, Proceedings of ISMRM 2000, Denver, Col., USA., April 2000, pp 543
  7. C. Studholme E. Novotny, R. Stokking, J.S. Duncan, I.G. Zubal, D. Spencer, Alignment of Functional Data Acquired Before and After Intra-Cranial Electrode Implantation using Non-Rigid MRI Registration, Proceedings of ISMRM 2000, Denver, Col., USA, April 2000, pp585.
  8. C. Studholme, V. Nicolson, and M. Weiner. Building whole brain maps of atrophy from multi-subject longitudinal studies using free form deformations. In Proceedings of ISMRM 2001, Glasgow, Scotland, 2001.
  9. O. Skrinjar, C. Studholme, A. Nabavi, J. Duncan, Steps Toward a Stereo-Camera-Guided Biomechanical Model for Brain Shift Compensation, Proceedings of Information Processing in Medical Imaging, UC Davis, June 2001, pp 183-189, Springer-Verlag, LLNCS 2082, ISBN 3-540-42245-5.
  10. C. Studholme, V. Cardenas Nicolson, N. Schuff, and M. W. Weiner. High resolution free form deformation analysis of atrophy from longitudinal MRI studies of mild cognitive impairment. In Proceedings of Functional Mapping of the Human Brain 2001, 2001.
  11. M Weiner, C. Studholme, V.A. Cardenas, N. Schuff, “Quantification of Normal Human Brain Aging by Serial MRI”, 2nd Neurobiology of Aging Confernce, San Diego, Novemeber 2001.
  12. M. Weiner, An Du, C. Studholme, V. Cardenas-Nicolson, N. Schuff, B. Miller, J. Kramer, W. Jagust, B.R. Reed, H. Chui, “Longitudinal Changes of Brain Structures in Healthy Aging and AD”, the 54th Annual Meeting of the American Academy of Neurology, Denver, 2002.
  13. A. Du, N. Schuff, C. Studholme, W. J. Jagust, B. L. Miller, M. Weiner, Differential Gray and White Matter Losses in Different Brain Lobes in Alzheimer’s Disease, In: Proceedings of ISMRM 2002, Hawaii, May 2002.
  14. N. Schuff, S. Matsumoto, J. Kmiecik, F. Ezekiel, C. Studholme, A. Du, H. Rosen, J. Kramer, G-H Jahng, B. L. Miller, M. Weiner. Reduced Blood Flow in Addition to Volume Loss of Cortex in Alzheimer’s Disease, In: Proceedings of ISMRM 2002, Hawaii, May 2002.
  15. C. Studholme, V. Cardenas, N. Schuff, M. Krishnan, H. Chui, and M.W. Weiner. The effects of cerebrovascular and Alzheimer disease on patterns of ventricular expansion rate derived from serial MRI. In: Proceedings of ISMRM 2002, Hawaii, May 2002.
  16. V. Cardenas, C. Studholme, R. Blumenfeld, D. Sacrey, M. Weiner, D.J. Meyerhoff, Detecting Chronic Alcohol Induced Structural Differences in the Human Brain Using Deformation Morphometry, In: Proceedings of Functional Mapping of the Human Brain, Sendai, Japan, June 2002.
  17. V. Cardenas, C. Studholme, R. Blumenfeld, D. Sacrey, M. Weiner, D.J. Meyerhoff, In: Detecting Brain Structure Changes Due to Chronic Alcohol Consumption and HIV infection using Tensor Morphometry, In: Proceedings of the Research Society on Alcoholism, San Francisco, June 2002.
  18. C. Studholme, Valerie Cardenas, Rob Blumenfeld, William Jagust, Helena Chui, Joel Kramer, Howard Rosen, Norbert Schuff, Bruce Miller, Michael Weiner, A High Resolution Tensor Morphometry Study of Brain Shape Differences Induced by Alzheimer’s Disease and Normal Aging, In: The 8th International Conference on Alzheimer’s Disease and Related Disorders, Stockholm, July 2002.
  19. R.G. Miller, R.R. Rule, C. Studholme, M.W. Weiner, High-Resolution MRI Morphometry Maps Longitudinal Atrophy in ALS Brains, In Proceedings The International Symposium on ALS, Oct 2002, Melbourne,
  20. R.R. Rule, C. Studholme, M.W. Weiner, R.G. Miller, High-Resolution MRI Morphometry Maps Longitudinal Atrophy in ALS Brains, In Proceedings of the Society for Neuroscience, Nov 2-7 2002, Orlando FL.
  21. V. Cardenas, D. Meyerhoff, L. Chao, J.C. Rothland, C. Studholme, L.J. Rogers, H. Lampiris, M. Cheseny, M. Weiner, Persistent Brain Injury in HIV patients on ART, Proceedings of 10th Conference on Retroviruses and Opportunistic Infections, Feb 10-14, 2003.
  22. E. Song, V. Cardenas, D. Sacrey, R. Blumenfeld, M. Weiner, C. Studholme, “MRI Tissue Segmentation Incorporating a Bias Field Modulated Smoothness Prior”, In Proceedings SPIE Medical Imaging, 2003.
  23. N. Schuff, S. Matsumoto, J. Kmiecik, C. Studholme, A.T. Du, B.L. Miller, J.H. Kramer, W.J. Jagust, H.C. Chui, F. Ezekiel, M.W. Weiner, “Cerebral Perfusion in AD and Subcortical Ischemic Vascular Dementia using Arterial Spin Labeled MRI”, Proceedings of the 3rd International Congress on Vascular Dementia, Prague, Oct 23-26, 2003.
  24. D.J. Meyerhoff, V.A. Cardenas, E. Song, R. Blumenfeld, D. Truran, F. Ezekiel, C. Studholme, J. Rothlind, J. Lindgren, M.W.Weiner. Brain morphologic changes suggest persistent brain injury in treated HIV-infected individuals. International Society of Magnetic Resonance in Medicine Ninth Annual Meeting (2003). Proceedings ISMRM 2003.
  25. V. Cardenas, L. Chao, C. Studholme, R. Blumenfeld, D. Meyerhoff, M Weiner, Detecting Associations Between P3a and Brain Structure Using Deformation Morphometry, Proceedings of Human Brain Mapping, New York, 2003.
  26. V. Cardenas, D. Meyerhoff, L. Chao, J.C. Rothland, C. Studholme, L.J. Rogers, H. Lampiris, M. Cheseny, M. Weiner, Persistent Brain Injury in HIV patients on ART, Proceedings of 10th Conference on Retroviruses and Opportunistic Infections, Feb 10-14, 2003.
  27. C. Studholme, V. Cardenas, A. Maudlsey, M.W. Weiner. High Accuracy Automated Template Based Correction of Brain MRI Intensity Distortion. In: Proceedings of ISMRM 2003, Toronto, Canada, July 2003.
  28. Meyerhoff, D.J., Cardenas, V., Studholme, C., Blumenfeld, R., Truran, D., Ezekiel, F., Lampiris, H., Rothlind, J., Lindgren, J., and Weiner, M.W. “Evidence for Brain Damage in Treated HIV-Infected Individuals”. In 55th Annual Meeting of the American Academy of Neurology (AAN), Honolulu, HI (2003).
  29. L.L. Chao, C. Studholme, D. J. Meyerhoff, and M.W. Weiner, “Evidence of CNS impairment in HIV+ patients on effective antiretroviral therapy”. Cognitive Neuroscience 10th annual meeting (also published in Journal of Cognitive Neuroscience, Supplement) (2003).
  30. S. Gazdzinski, T.C. Durazzo, C. Studholme, E. Song, R. Blumenfeld, F. Ezekiel, K.A. Gordon, and D.J. Meyerhoff. “Recovery of regional brain tissue volumes in short-term abstinent alcoholics.” Research Society on Alcoholism Annual Scientific Meeting (2003). Alcoholism: Clinical and Experimental Research.
  31. C. Studholme, “Capturing Brain Shape in Neurodegenerative Disease using Image Registration”, 2003 World Congress of Biomedical Physics and Biomedical Engineering, Sydney, Australia, August 26th, 2003.
  32. V.A. Cardenas, E. Song;,C. Studholme, R. Blumenfeld, D. Truran, M.W. Weiner, D.J. Meyerhoff. Effects of chronic active heavy drinking, family history, and binge drinking on regional brain tissue volumes. Research Society on Alcoholism Annual Scientific Meeting (2003). Alcoholism: Clinical and Experimental Research..
  33. C. Studholme, C. Drapaca, V. Cardenas, M. Weiner, “Challenges and Progress Toward Quantitative Deformation Morphometry of Gyral Anatomy”, 2nd International Symposium on Biomedical Imaging, Arlington VA, 16thApril 2004.
  34. C. Studholme, K. Yaffe, V. Cardenas, B. Miller, M Weiner. A Deformation Morphometry Study of Brain Structure in Lewy Body Dementia, Proceedings of Human Brain Mapping, 2004.
  35. V. Cardenas, Rothland, Chow, Studholme, Meyerhoff, Weiner, Detecting associations between executive function deficits and brain structure in Heavy Drinkers Using Automated Morphmetry, Proc. Proceedings of Human Brain Mapping 2004, Hungary.
  36. C. Studholme, K. Yaffe, V. Cardenas, N. Schuff, B. Miller, M Weiner. A Using Deformation Morphometry to Investigate Tissue Loss in Dementia with Lewy Bodies, 9th International Conference on Alzheimer’s Disease and Related Disorders, July 2004.
  37. V.Cardenas, J. Rothland, L. Chow, C. Studholme, M. Weiner, D. Meyerhoff, Associations between executive function deficits and brain structure in Heavy Drinkers, Proc. Research Society on Alcoholism Annual Scientific Meeting 2004, Vancouver, Canada.
  38. C. Studholme, C. Rodriguez-Carranza, V. Cardenas, B. Iordanova, S. Miller, P. Mukherjee1, O. Glenn, D. Vigneron, J. Barkovich, A Deformation Morphometry study of the Influences on the Pattern of Brain Tissue Development in Premature Neonates, Proceedings of Human Brain Mapping 2005.
  39. V A. Cardenas, L L. Chao, C. Studholme, J. Kramer, B. Miller, M.W. Weiner, “Relationships Between Brain Structure, Object Naming, and Memory in Dementia”, Proc. Human Brain Mapping, Toronto, 2005.
  40. Colin Studholme, Valerie Cardenas, Harry Lampiris, Dieter Meyerhoff, Michael Weiner, Evidence for Ongoing Brain Tissue Volume Loss in HIV+ Subjects on Anti retro-viral Therapy, Poceedings of Human Brain Mapping, 2006.
  41. V. A. Cardenas, A. Boxer, L. L. Chao, M. L. Gorno-Tempini, B. Miller, M. W. Weiner, and C. Studholme, "Subcortical and midbrain atrophy in frontotemporal dementia," 12th Annual Meeting of the Organization for Human Brain Mapping, Florence, Italy, June 2006.
  42. Pratik Mukerjee, Hana Lee, Srivathsa Veeraraghavan, Duan Xu, Michele Meeker, Jamshid Ghajar, Geoffrey T. Manley, Colin Studholme, “Regionally-Specific Atrophy Following Traumatic Brain Injury Revealed by Deformation Morphometry of Serial 3 Tesla Volumetric MRI” Proceedings of ISMRM 2007.
  43. Colin Studholme, L Stables, M. Weiner, “Removing Gradient Non-Linearity Effects in Deformation Morphometry of High Field Serial MRI”, Proceedings of ISMRM 2007.
  44. P. Mukherjee, H. Lee, S. Veerarhagavan, D. Xu, M. Meeker, J. Ghajar, G. Manley, and C. Studholme, "Regionally-specific atrophy following traumatic brain injury revealed by deformation morphometry of serial 3 Tesla volumetric MRI," 13th Annual Meeting of the Organization for Human Brain Mapping, Chicago, IL, June 2007.
  45. A. Jackowski, C. Studholme, H. Douglas-Palumberi, and J. Kaufman, "New structural brain findings in maltreated children with PTSD using deformation tensor morphometry: a preliminary report," 14th Annual Meeting of the Organization for Human Brain Mapping, Melbourne, Australia, June 2008.
  46. F. Rousseau, K. Kim, and C. Studholme, "An example-based approach for high-resolution reconstruction of developing brain MRI," Imaging the Early Developing Brain: Challenges and Potential Impact, Workshop at MICCAI 2008, New York, NY, September 2008.
  47. P. A. Habas, K. Kim, C. E. Rodriguez-Carranza, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Abnormal sulcal formation in fetuses with ventriculomegaly identified by surface curvature mapping from motion-corrected clinical MRI," 15th Annual Meeting of the Organization for Human Brain Mapping, San Francisco, CA, June 2009.
  48. P. A. Habas, K. Kim, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Atlas-based segmentation of the fetal brain from reconstructed 3D clinical MRI: Quantitative validation in young fetuses," 15th Annual Meeting of the Organization for Human Brain Mapping, San Francisco, CA, June 2009.
  49. K. Kim, P. A. Habas, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Evaluation of clinical fetal brain MRI motion correction for 3D image formation," 15th Annual Meeting of the Organization for Human Brain Mapping, San Francisco, CA, June 2009.
  50. D. Chandramohan, P.A. Habas, K. Kim, O.A. Glenn, A.J. Barkovich, C. Studholme, Cortical Thickness Mapping of the Human Fetal Brain in Utero from Motion-Corrected Clinical MRI: Preliminary Results, 15th Annual Meeting of the Organization for Human Brain Mapping, San Francisco, CA, June 2009.
  51. VA Cardenas; S Gazdzinski; C Studholme; T Durazzo; A Mon; DJ Meyerhoff ,Common Pattern of Brain Atrophy Underlying Alcohol and Alcohol+Tobacco Dependence, 15th Annual Meeting of the Organization for Human Brain Mapping, San Francisco, CA, June 2009.
  52. Cardenas VA, Durazzo T, Gazdzinski S, Mon A, Studholme C, Meyerhoff DJ: Brain morphology at treatment entry associated with maintenance of abstinence, 32nd Annual Scientific Meeting of the Research Society on Alcoholism, June 2009.
  53. Cardenas VA, Gazdzinski S, Studholme C, Durazzo T, Mon A, Meyerhoff DJ: Common pattern of brain atrophy underlying alcohol and alcohol+tobacco dependence, 32nd Annual Scientific Meeting of the Research Society on Alcoholism, June 2009.
  54. P. A. Habas, J. M. Corbett-Detig, K. Kim, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Global and regional patterns of tissue volume growth in the normal fetal brain from in utero MRI," 16th Annual Meeting of the Organization for Human Brain Mapping, Barcelona, Spain, June 2010.
  55. J. M. Corbett-Detig, P. A. Habas, K. Kim, V. Rajagopalan, A. Roosta, D. Chandramohan, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Quantitative 3-D measurement of subplate growth in-utero in the normal human fetus," 16th Annual Meeting of the Organization for Human Brain Mapping, Barcelona, Spain, June 2010.
  56. A. Roosta, P. A. Habas, K. Kim, J. Konkle, J. M. Corbet-Detig, F. Rousseau, O. A. Glenn, and C. Studholme, "Detection of early brain folding patterns of the normal human fetuses in utero," 16th Annual Meeting of the Organization for Human Brain Mapping, Barcelona, Spain, June 2010.
  57. V. Rajagopalan, P. A. Habas, K. Kim, J. M. Corbett-Detig, F. Rousseau, O. A. Glenn, A. J. Barkovich, and C. Studholme, "Using tensor based morphometry to explore differential tissue growth patterns in normal fetal brains," 16th Annual Meeting of the Organization for Human Brain Mapping, Barcelona, Spain, June 2010.
  58. J. A. Scott, P. A. Habas, K. Kim, A. Chau, K. J. Poskitt, A. J. Barkovich, S. P. Miller, O. A. Glenn, and C. Studholme, "Cerebral volumes of prematurely born neonates and fetuses do not differ at similar gestational ages," 17th Annual Meeting of the Organization for Human Brain Mapping, Quebec City, Canada, June 2011.
  59. K. S. Hamzelou, J. A. Scott, P. A. Habas, V. Rajagopalan, K. Kim, A. J. Barkovich, O. A. Glenn, and C. Studholme, "3D morphometric analysis of human cerebellar development during mid-gestation: an in utero MRI study," 17th Annual Meeting of the Organization for Human Brain Mapping, Quebec City, Canada, June 2011.
  60. P. A. Habas, J. A. Scott, V. Rajagopalan, K. Kim, F. Rousseau, A. J. Barkovich, O. A. Glenn, and C. Studholme, "Detection of hemispheric asymmetries during early folding by surface-based analysis of fetal MRI," 17th Annual Meeting of the Organization for Human Brain Mapping, Quebec City, Canada, June 2011.
  61. V. Rajagopalan, J. A. Scott, P. A. Habas, K. Kim, J. M. Corbett-Detig, F. Rousseau, A. J. Barkovich, O. A. Glenn, and C. Studholme, "Quantifying asymmetry in local tissue growth patterns in normal fetal human brain in utero," 17th Annual Meeting of the Organization for Human Brain Mapping, Quebec City, Canada, June 2011.
  62. P. A. Habas, J. A. Scott, V. Rajagopalan, K. Kim, F. Rousseau, A. J. Barkovich, O. A. Glenn, and C. Studholme, "Detection and mapping of delays in early cortical folding in fetuses with ventriculomegaly from in utero MRI," 19th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Montreal, Canada, May 2011.
  63. F. D. Jacob, P. A. Habas, K. Kim, J. M. Corbett-Detig, D. Xu, C. Studholme, and O. A. Glenn, "Fetal hippocampal development: analysis by magnetic resonance imaging volumetry," 63rd Annual Meeting of the American Academy of Neurology, Honolulu, HI, April 2011.