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Tag: vaccines
December 21, 2020
Broad Cross-National Public Support for Accelerated COVID-19 Vaccine Trial Designs
Results from a cross-national survey conducted in Australia, Canada, Hong Kong, New Zealand, South Africa, Singapore, the UK, and the US in May 2020 (n = 5920) showed that most respondents preferred for scientists to conduct accelerated trials (human challenge trials, 75%; Phase II/III safety, immunogenicity, and efficacy integrated trials, 63%) over traditional vaccine trials for COVID-19….
US Public Attitudes Toward COVID-19 Vaccine Mandates
61.4% of US adults who completed a Gallup Panel web survey between September 14 and 27, 2020 indicated they would likely get a COVID-19 vaccine. Nearly one-half (48.6%) of respondents thought requiring a COVID-19 vaccination for children attending school was acceptable. Individuals likely to get a COVID-19 vaccine accepted mandates at higher rates than those…
The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Moderna COVID-19 Vaccine — United States, December 2020
The Advisory Committee on Immunization Practices issued an interim recommendation for use of the Moderna COVID-19 vaccine in persons aged ≥18 years for the prevention of COVID-19 on December 19, 2020. Vaccination with the Moderna COVID-19 vaccine consists of 2 doses administered intramuscularly 4 weeks apart. Vaccine efficacy after 2 doses was 94.1% in preventing…
December 18, 2020
Understanding COVID-19 Vaccine Demand and Hesitancy: A Nationwide Online Survey in China
Results from a nationwide survey conducted in May 2020 in China indicated that many respondents expressed probable (55%) or definite (29%) intent to receive a COVID-19 vaccine. The study examined the applicability of the health belief model to vaccine demand and hesitancy, and found that perceived benefits and barriers (namely related to efficacy and outcomes)…
December 16, 2020
Global, Regional, and National Estimates of Target Population Sizes for Covid-19 Vaccination: Descriptive Study
A descriptive study of target populations for SARS-CoV-2 vaccination among member states of the WHO found that target population sizes vary by vaccination goal and geographic region. Europe has a high share of essential workers (63 million, 9%) and people with underlying conditions (266 million, 37%) who may be important to vaccinate to maintain societal…
December 14, 2020
The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Pfizer-BioNTech COVID-19 Vaccine — United States, December 2020
On Dec 12, 2020, the Advisory Committee on Immunization Practices issued an interim recommendation for use of the Pfizer-BioNTech COVID-19 vaccine in persons in the US aged ≥16 years to prevent COVID-19. Vaccination consists of 2 doses administered intramuscularly 3 weeks apart. The recommendation was primarily informed by findings from a randomized, double-blind, placebo-controlled Phase II/III…
Predictors of COVID-19 Vaccine Acceptance across Time and Countries
Preprint, not peer-reviewed] A cross-sectional study using 25 national samples from 12 countries (total N = 25,334) identified male gender, trust in medical and scientific experts, and worry about the virus as consistent psychological correlates of reported vaccine acceptance. Kerr et al. (Dec 11, 2020). Predictors of COVID-19 Vaccine Acceptance across Time and Countries. Pre-print…
COVID-19 Vaccine Hesitancy in the UK: The Oxford Coronavirus Explanations, Attitudes, and Narratives Survey (OCEANS) II
An online survey conducted in fall 2020 among 5,114 adults in the UK reported 72% were willing to be vaccinated with a COVID-19 vaccine, 17% were very unsure, and 12% were strongly hesitant. Higher levels of vaccine hesitancy were associated with lower adherence to social distancing guidelines and a lower likelihood of taking a diagnostic…
December 11, 2020
Intention of health care workers to accept COVID-19 vaccination and related factors: a systematic review and meta-analysis
[Pre-print, not peer reviewed] In a systematic review examining the intention of healthcare workers (HCW) to accept COVID-19 vaccination (11 studies, 8,847 HCWs), the overall proportion of HCWs that intend to accept COVID-19 vaccination was 56% (95% CI 44-68%) with a wide range among studies from 28% to 82%. Factors associated with increased HCW willingness…
December 10, 2020
Safety and Efficacy of the BNT162b2 MRNA Covid-19 Vaccine
Results of the phase 3 double-blind, randomized, placebo-controlled trial for the BioNTech and Pfizer mRNA vaccine BNT162b2 (n=21,720 in vaccine group, and 21,728 in placebo group) showed a vaccine efficacy of 95% (95% CI 90.3-97.6), with 8 cases of COVID-19 (1 severe case) in the vaccine group and 162 cases (9 severe cases) in the…
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