Investigator Profile

Dr. Paquette is an Assistant Professor in the Center for Developmental Biology & Regenerative Medicine (CDBRM) at the Seattle Children’s Research Institute and a member of the University of Washington School of Medicine Department of Pediatrics (Division of Genetic Medicine). Dr. Paquettes primary research interest is to use ‘omics data generated from the placenta to better understand the developmental origins of health and disease (DOHAD). Dr. Paquette received her PhD from Dartmouth’s Program in Experimental and Molecular Medicine under the mentorship of Dr. Carmen Marsit. She has expertise and formal training in molecular epidemiology, epigenomics, transcriptomics, toxicology, computational biology, and placental biology. Dr. Paquette joined the Center for Developmental Biology in August 2020.

Professional Information:

Education and Postgraduate Training

BS, Chemistry, Biochemistry
Worcester Polytechnic Institute, Worcester MA

 Ph.D, Toxicology and Pharmacology
 Program of Experimental and Molecular Medicine
 Geisel School of Medicine at Dartmouth College, Hanover, NH
 Mentor: Carmen Marsit, PhD 

 Post-Doctoral Fellowship
 Institute for Systems Biology
 Mentor: Nathan Price, PhD 

Professional Organizations

 Perinatal Research Society
 International Society for Environmental Epidemiologists
 US Developmental Origins of Health and Disease (DOHAD) Society
 Society for Reproductive Investigators 

Active and Completed Research Funding

 NIH:NICHD R00HD096112 (Paquette-PI)
  08/01/2020 – 08/01/2023
 Title: The role of Corticotrophin Releasing Hormone on Placental Transcriptional Networks and Birth Timing
 Role: Principal Investigator 

 Catalytic Collaboration Grant (Paquette- CO PI)
 Brotman Baty Institute
 02/01/2022 – 1/31/2023
 Title: Assessing how Phthalate Exposure Disrupts Placental Transcriptional Regulation using Chromatin Profiling
 Role: Co-Principal Investigator 

 NIH/NIEHS R01 ES025169-06 (Sathyanarayana-PI)
 04/01/2022 – 04/01/2027
 Title: TIDES III: Endocrine Disruption, Hormones, and Sex Differences in Adolescent Airway Health
 Role: Co-Investigator 

 NIH ECHO PROGRAM: Opportunities and Infrastructure Grant (Paquette-PI)
 09/01/2019 – 09/01/2021
 Title: Leveraging Transcriptional Regulatory Networks for Exposure Analysis.
 Role: Principal Investigator 

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