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In addition to the regular class meetings, graduate students enrolled in Biological Frameworks for Engineers are required to attend a weekly 60-minute "journal club" session. (The journal club is optional for undergraduates.) Each journal club session is an instructor-led discussion of a piece of literature handed out a week earlier along with a study guide. Sample assignments are listed below.
 Introduction to the "Breakthroughs in Biology" series (MS Word)
(required for graduate students enrolled in EE 546; optional for everyone else)
| Article List |
Study Guide |
M. B. Elowitz and S. Leibler, "A synthetic oscillatory network of transcriptional regulators," Nature 403: 335-338, 2000.
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Study Guide |
Walter Gilbert and Benno Müller-Hill, “The lac operator is DNA,” Proceedings of the National Academy of Sciences USA 58: 2415-2421, 1967.
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Study Guide |
| V. M. Ingram, "Gene mutations in hæmoglobin: the chemical difference between normal and sickle-cell hæmoglobin," Nature 180: 326-328, 1957. |
Study Guide |
| E. R. Kandel, "Calcium and the control of synaptic strength by learning," Nature 293: 697-700, 1981. |
Study Guide |
| K. P. Lemon and A. D. Grossman, "Localization of bacterial DNA polymerase: evidence for a factory model of replication," Science 282: 1516-1519, 1998. |
Study Guide |
| S. L. Lindstedt et al., "Limitations to aerobic performance in mammals: interaction of structure and demand," International Journal of Sport Medicine 9: 210-217, 1988. |
Study Guide |
| H.-R. Lüscher et al., “How the size of motoneurones determines their susceptibility to discharge,” Nature 282: 859-861, 1979. |
Study Guide |
| G. J. Lutz and L. C. Rome, “Built for jumping: the design of the frog muscular system,” Science 263: 370-372, 1994. |
Study Guide |
| E. M. Purcell, “Life at low Reynolds number,” American Journal of Physics 45: 3-11, 1977. |
Study Guide |
| F. Sanger et al., "DNA sequencing with chain-terminating inhibitors," Proceedings of the National Academy of Sciences USA 74: 5463-5467, 1977. |
Study Guide |
| Y. Shav-Tal et al., “Dynamics of single mRNPs in nuclei of living cells,” Science 304: 1797-1800, 2004. |
Study Guide |
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