The Immunology, Retrovirology and Cure Core provides advanced tools and training for evaluating humoral and cellular responses to HIV infection.
The assays, reagents, technology, and education offered by the Core support CFAR research involved with the prevention, detection, and treatment of HIV infection and AIDS. Most Core services are used by investigators to help quantify immune responses in plasma, serum, secretions, or cells from HIV-infected patients or lentivirus-infected nonhuman primates. The types and levels of support available from Core faculty are flexible—from quick telephone or email troubleshooting consultations to intensive group trainings on specific technologies; from simple cytometry experiments using one to three colors to cutting-edge experiments using up to 18 colors; and from rapid immune analysis of a few samples for a pilot assessment or hypothesis generation to longer-term collaborations involving joint study design and execution. Services are accessible through our four subcores:
Keith Jerome, MD, PhD
Core Co-Director
Florian Hladik, PhD
Core Co-Director
Mucosal Immunity and Non-Human Primate Immunology Subcore Director
Email: fhladik at fredhutch.org
Stephen De Rosa, MD
Cellular Immunity and Flow Cytometry Subcore Director
Email: sderosa at fredhutch.org
Telephone: 206-667-1681
Noah Sather, PhD
Core Associate Director
Humoral Immunity Subcore Director
Email: noah.sather at seattlechildrens.org
Deborah Fuller, PhD
Non-Human Primate Immunology Subcore Director
Email: fullerdh at wanprc.org
Sandra Dross, PhD
Non-Human Primate Immunology Subcore Co-Director
Email: sdross at uw.edu
Michael Gale, PhD
Quantitative RNAseq and High Content Data Analysis Subcore Director
Email: mgale at uw.edu