Global WACh

HIV and Co-Infections


March 4, 2026

RISE collaborators attend launch meeting in Kenya for HIV/ART exposure on child neurodevelopment research

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RISE collaborators from multiple research institutes met in Nairobi, Kenya.

From February 2nd-4th, collaborators affiliated with “Researching Interventions and Implementation Strategies to Evaluate the Health and Development of Children Affected by HIV (RISE)” met in Nairobi, Kenya for its official launch meeting. It was an exciting time for collaborators to meet in-person, understand the program goals and individual responsibilities, and participate in meaningful scientific discussions. Collaborators left this short, but impactful meeting motivated, engaged, and focused.

Awarded in late 2025, RISE aims to evaluate tools for screening children for neurodevelopmental delays and to identify interventions to optimize neurodevelopment among children with and without in-utero HIV/ART exposure in Botswana, Kenya, and Zimbabwe. It includes three distinct research Projects and three Cores that provide shared resources, focusing on scientific administrative support, data management and analysis, and dissemination and stakeholder engagement, to facilitate the Projects. Investigators come from partner institutions in Kenya (University of Nairobi, Kenyatta National Hospital, UW-Kenya, Kenya Medical Research Institute), Zimbabwe (Zvitambo, Queen Mary University, London), Botswana (Botswana Harvard Partnership, Mass General Hospital), Mayo Clinic, Seattle Children’s Hospital, University of California, San Diego (UCSD), Emory University, and Indiana University. (more…)


February 23, 2026

MIND study collaborators attend 3rd annual meeting for child development research in Kenya

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Investigators and administrators from multiple Kenyan and U.S. institutions who support the MIND study.

In early February, nearly 40 collaborators affiliated with the “Drug, microbiome, and immune determinants of birth and neurodevelopmental outcomes in children with exposure to HIV infection (MIND) study” attended the 3rd annual MIND meeting in Nairobi, Kenya. Launched in early 2023, MIND leveraged three birth cohorts in Kenya to build new studies of neurodevelopment. In addition, MIND supports two “Cores” that provide access to technologies, services, training, and consultation to successfully execute the studies, particularly focused on neurodevelopmental assessments. (more…)


February 2, 2026

Researchers convene to disseminate findings that can inform future HIV and TB care in Kenya

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Researchers convened in Nairobi, Kenya on November 14, 2025.

In November 2025, researchers on multiple UW and Kenyatta National Hospital (KNH) collaborative projects focusing on HIV and tuberculosis (TB) convened in Nairobi to share key findings and discuss future directions. Dr. Sylvia LaCourse (Associate Professor with joint appointments in Department of Medicine – Allergy & Infectious Diseases and Global Health) presented on the role of HIV on TB infection detection, prevention strategies and immunity in pregnant women and children. The shared results concluded more than 10 years of dedicated work by collaborators at UW (Dr. Grace John-Stewart, Dr. Tom Hawn, Dr. Barbra Richardson, Dr. Irene Njuguna), Emory University (Dr. Cheryl Day, Dr. Lisa Marie Cranmer), University of Nairobi (Dr. Lisa Maleche-Obimbo), and Kenyatta National Hospital (Dr. John Kinuthia). Future directions include considerations for policy to guide HIV and TB treatment and preventative strategies to improve health outcomes in Kenya.
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December 19, 2025

MIND study collaborators convene at UW to discuss future directions for childhood neurodevelopment research

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MIND meeting collaborators at the University of Washington

Earlier this month, the Drug, microbiome, and immune determinants of birth and neurodevelopmental outcomes in children with exposure to HIV infection (MIND) study collaborators based at the University of Washington convened for a day of knowledge sharing and discussions on projects focusing on adverse birth and neurodevelopmental outcomes in young children exposed to HIV but are uninfected (CHEU). (more…)


December 5, 2025

Researchers receive major grant to study impact of HIV/ART exposure on child neurodevelopment

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Multiple Principal Investigators Grace John-Stewart, Dalton Wamalwa, Kathleen Powis, and Andrew Prendergast leading the newly awarded U19 RISE Project

An international research team with Global WACh and partners in the U.S., Kenya, Zimbabwe, and Botswana received a five-year long $36 million dollar grant from the National Institute of Health to better understand how HIV or antiretroviral (ART) exposure in utero influences child health outcomes, including neurodevelopment.

“Researching Interventions and Implementation Strategies to Evaluate the Health and Development of Children Affected by HIV (RISE)” is a large NIH-funded U19 Program to evaluate tools for screening children for neurodevelopmental delays and to identify interventions to optimize neurodevelopment among children with and without in utero HIV/ART exposure. The RISE Program includes three distinct research Projects and three Cores that provide shared resources, focusing on scientific administrative support, data management and analysis, and dissemination and stakeholder engagement, to facilitate the Projects.
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November 13, 2025

Dr. Dickens Onyango receives Fogarty Emerging Global Leader Award to support research career development in TB prevention among people living with HIV

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Congratulations to Dr. Dickens Onyango (Deputy Director of Medical Services, Kisumu County Health Department and visiting research scientist at Kenyatta National Hospital, Kenya) for receiving a National Institute of Health Fogarty Emerging Global Leader Award for “Enhancing Adherence and Completion of the Three-Month Isoniazid with Rifapentine (3HP) Tuberculosis Preventive Therapy Regimen Through Biomarker-Guided Adherence Counselling (ACT-TPT).” Collaborating institutions include the Kisumu County Department of Health, Kenyatta National Hospital, and University of Washington.

The award supports an intensive, mentored research career development experience that will allow Dr. Onyango to further develop and expand skills in qualitative research, human-centered design, randomized controlled trials, and advanced implementation science methods to evaluate multicomponent interventions while growing in his career in tuberculosis (TB) prevention among people living with HIV (PLHIV).  Click here to watch Dr. Onyango’s ‘Breakfast with WACh’ lecture from March 2025 that summarizes prior research that this project builds upon. (more…)


October 27, 2025

Dr. Irene Njuguna and Dr. Grace John-Stewart lead new study on the effects of HIV and environmental exposures on pediatric neurodevelopmental outcomes

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The population of children who are HIV-exposed but uninfected (CHEU) is growing, and the majority live in Eastern and Southern Africa where exposure to environmental toxins (lead, heavy metals, and pesticides) is high.  Understanding the combined impact of HIV and environmental exposures on child health outcomes is critical to identify approaches to mitigate risks and provide treatment for CHEU.

Global WACh Co-Directors, Dr. Irene Njuguna and Grace John-Stewart, are Multiple Principal Investigators of a new five-year National Institutes of Health award for “Impact of HIV and toxic metals exposure on neurodevelopment at school age (HOPE-X).” The study leverages an existing cohort of Kenyan children (HOPE) who were enrolled at 6 weeks of age and followed to 3 years, enabling the research team to extend follow-up to 8 years old to study the longer-term impact of HIV and environmental exposures on neurodevelopmental outcomes. The team will also explore the concentrations of pesticides and other toxic metals (mercury, cadmium, manganese and arsenic) in biological samples. (more…)


July 15, 2025

Research Scientist Dr. Emily Begnel receives early career award to study antimicrobial resistance and its effects on gut health and HIV exposure in children

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Congratulations to Dr. Emily Begnel, Research Scientist with Global WACh, for receiving a Thrasher Research Fund Early Career Award to fund “The prevalence of antimicrobial resistance and effects on gut health among children who are HIV-exposed but uninfected.” The award funds early career investigators and their development towards independent research in child health.  Dr. Begnel will conduct her research under the mentorship of Drs. Jennifer Slyker and Patricia Pavlinac (UW Global Health and Epidemiology), and collaborate with Dr. Ana Weil (UW School of Medicine) and the Weil Lab.

Antimicrobial resistance (AMR) is rising globally and threatens public health by decreasing effectiveness of antibiotics in treating infections. Children who are HIV-exposed receive the antibiotic cotrimoxazole to prevent a range of bacterial infections; however, there is concern that it may contribute to the development of AMR in these children. There is urgency to better understand the dynamics of AMR development and spread, particularly among children in low- and middle-income countries where AMR is prevalent. Pathogens can transfer resistance genes to the bacteria in the gut microbiome, potentially contributing to long-term AMR. (more…)


June 6, 2025

Global WACh hosts annual Student Poster Symposium highlighting graduate student research

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On Wednesday, June 4th, Global WACh hosted its annual Student Poster Symposium to highlight graduate student research affiliated with our center.  Dozens of UW faculty, staff, students attended to learn about 17 students’ projects that fulfilled academic capstone and dissertation requirements, while providing opportunities to gain knowledge and build marketable skillsets in the field of maternal-child health.

The majority of presenters are enrolled in the Global WACh Graduate Certificate Program and are graduating in the 2025 academic year. The certificate program offers opportunities for additional learning about woman, adolescent, and child health topics through 12 credits of coursework and a 90-hour capstone. We wish these students the very best in their future endeavors as public health professionals.

Additional posters featured master and doctoral degree capstones and dissertations that led to major advancements in the scientific field and were featured at the recent Conference on Retroviruses and Opportunistic Infections (CROI) held in San Francisco in March. CROI is considered the world’s leading HIV research meeting that attracts thousands of researchers and clinicians from around the globe – and is a fantastic stage to showcase our emerging early-stage researchers.

See the full list of participating students and their poster titles below. Click here to view the photo gallery courtesy of the Department of Global Health Communications team. (more…)


March 21, 2025

MIND collaborators convene for child development research in Nairobi, Kenya

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MIND collaborators at the Palacina Suites Hotel in Nairobi, Kenya. Photo: Mugo Mureithi

In January, nearly 50 collaborators affiliated with the Drug, microbiome, and immune determinants of birth and neurodevelopmental outcomes in children with exposure to HIV infection (MIND) study attended the 2nd annual convening in Nairobi, Kenya. Launched in early 2023, MIND leverages three ongoing childhood development studies in Kenya and supports two core groups that provide access to technologies, services, training, and consultation to successfully execute the studies.

It is a remarkable partnership involving several investigators and administrators from UW/Global WACh, Kenyatta National Hospital, University of Nairobi, Kenya Medical Research Institute, Emory University, Fred Hutch, Seattle Children’s Hospital, and Makerere University who share knowledge and common resources to generate evidence on biological factors that may cause adverse birth and neurodevelopmental outcomes in young children exposed to HIV but are uninfected. The two-day convening provided a forum to share progress since the inaugural meeting in January 2024 and team retreat at UW in October 2024, and to discuss future directions of research collaborations. (more…)



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