Research
July 16, 2020
Dr. Arianna Means awarded NIH grant to develop strategies to improve pediatric treatment guideline adherence at healthcare facilities
Categories: Awards, Gut Health and Child Survival, Research
Primary causes of death for children under five include pneumonia and diarrhea, and nearly half of deaths are attributable to undernutrition. It is estimated that over half of these deaths are preventable with simple, existing, appropriately applied evidence-based interventions, synthesized within pediatric clinical treatment guidelines. Although health workers in low-and-middle-income countries are trained on pediatric treatment guidelines, adherence to guidelines is often low and there is a need to identify strategies to improve quality of care in settings with the highest burden of preventable child deaths.
July 11, 2020
Global WACh Researchers Share Findings Virtually at AIDS 2020
Categories: Conferences, HIV and Co-Infections, Research
In response to the COVID-19 pandemic, the 23rd International AIDS Conference (AIDS 2020) moved from San Francisco, CA to a virtual platform this year. The largest conference on HIV/AIDS research was held from July 6-10, 2020 and gathered researchers from around the world. Global WACh faculty, staff, and students within the HIV and Co-Infections Scientific Priority Area shared 9 poster abstracts, 1 oral abstract, and moderated 1 oral poster discussion session on an innovative and interactive global platform to influence discussions on HIV science, research, and policy. See the abstract titles below and click on the titles to learn more.
July 1, 2020
Randomized controlled trial of isoniazid to prevent primary TB infection in Kenyan HIV-exposed uninfected infants published in Clinical Infectious Diseases
Categories: HIV and Co-Infections, Publication, Research
Mother and infant pair at a health facility in Kenya. Paul J. Brown Photography.
Children born to mothers living with HIV are at an increased risk of tuberculosis (TB) infection, and young infants are particularly vulnerable to rapidly progressing to TB disease. Isoniazid preventative therapy (IPT) is used routinely to prevent TB after known TB exposure, but recent data suggest most transmission (70-90%) to young children occurs outside the household without identified exposure. Whether IPT can be used to prevent TB initial infection is unknown. (more…)
May 19, 2020
SEEMS-Nutrition estimates costs of early childhood development programs in Malawi
Categories: Children, Nutrition, Research
The Strengthening Economic Evaluation for Multi-sectoral Strategies for Nutrition (SEEMS-Nutrition) project, led by Dr. Carol Levin (Health Economist and Associate Professor, Global Health), has a unique opportunity to collect cost data alongside six on-going interventions and to generate new evidence on costs and cost-effectiveness of multi-sectoral projects in five country settings. Click here to read more about SEEMS-Nutrition.
The project applied its costing evaluation approaches to retrospectively estimate the costs and impact for an integrated agricultural, early childhood development, and school feeding randomized-control trial conducted in Malawi. (more…)
May 18, 2020
View recorded Global WACh research talks at UW
Categories: Gut Health and Child Survival, HIV and Co-Infections, Research, Talks and Events
Over the spring academic quarter at UW, Global WACh investigators and student research assistants shared their work across various presentation platforms across campus. Research span from assessing environmental enteric dysfunction on child health and survival to evaluating risks of depression among HIV-infected adolescent girls, to improved treatment of TB and HIV co-infections.
Click on the presentation titles below to access the recordings to view and learn more about our research. A list of upcoming virtual presentations can be found below.
March 11, 2020
Researchers share latest findings virtually at CROI 2020
Categories: HIV and Co-Infections, Research, Talks and Events
The annual Conference on Retroviruses and Opportunistic Infections (CROI) brings together top basic, translational, and clinical researchers from around the world to share the latest studies, important developments, and best research methods in the ongoing battle against HIV/AIDS and related infectious diseases. Due to concerns of the coronavirus (COVID-19) outbreak in the US, CROI 2020 was virtually held from March 8 to March 11, 2020. (more…)
December 5, 2019
Researchers present findings at the 2019 American Society of Tropical Medicine and Hygiene Conference
Categories: Conferences, Gut Health and Child Survival, Research
Last week, researchers from Global WACh’s Gut Health and Child Survival scientific priority area attended the 68th annual American Society of Tropical Medicine and Hygiene (ASTMH) Conference in National Harbor, MD. ASTMH founded in 1903, is the largest international scientific organization of experts dedicated to reducing the worldwide burden of tropical infectious diseases and improving global health. Experts envision a world free of tropical infectious diseases by generating and sharing scientific evidence, informing health policies and practices, fostering career development, recognizing excellence, and advocating for investment in tropical medicine/global health research.
Left to right: Hannah Atlas (MPH Student and Research Assistant), Dr. Rebecca Brander (Program Officer, Bill & Melinda Gates Foundation; Former Research Assistant), Dr. Christine McGrath (Assistant Professor, Global Health), Stephanie Tornberg-Belanger (PhD Epidemiology Student and Research Assistant)
Our researchers gave six oral presentations and presented six selected poster abstracts. Topics ranged from childhood diarrhea and enteric diseases to implementation science approaches for mass drug administration to factors of hospitalized-based child mortality. Scroll below to read each abstract and see photos from the conference. (more…)
November 25, 2019
New NIH study will test strategies to improve PrEP delivery to women receiving MCH services in Western Kenya
Categories: Awards, HIV and Co-Infections, PrEP, Research
Left to right: Dr. Grace John-Stewart, Dr. Pamela Kohler, Dr. Anjuli Wagner, Dr. John Kinuthia
In February 2020, Global WACh researchers of ongoing PrEP implementation studies are launching a new five-year study titled, “PrEP in pregnancy, accelerating reach and efficiency (PrEPARE).” PrEPARE is funded through a National Institute of Health supplement to the AGYW study, led by Global WACh Director, Dr. Grace John-Stewart and Dr. Pamela Kohler (Global Health, Psychosocial and Community Health) to evaluate PrEP adherence among adolescent girls and young women, and a K01 grant awarded to Dr. Anjuli Wagner (Acting Assistant Professor, Global Health).
Principal investigators, Drs. John-Stewart, Kohler, Wagner, and Dr. John Kinuthia (Kenyatta National Hospital, Nairobi, Kenya) will lead the PrEPARE study team that includes Global WACh researchers, Dr. Jillian Pintye (School of Nursing), Dr. Kristin Beima-Sofie (Global Health), Julia Dettinger (Global Health) and Laurén Gomez (Global Health).
November 13, 2019
Postdoctoral Fellow, Dr. Erica Lokken, joins Global WACh to study role of vaginal bacteria in HIV acquisition among Kenyan women
Categories: HIV and Co-Infections, Research
Global WACh is pleased to welcome new Postdoctoral Fellow, Dr. Erica Lokken, to our team at UW! Dr. Lokken successfully defended her PhD in Epidemiology dissertation in August and received a National Institute of Health F32 postdoctoral fellowship in October. This fellowship will support her long-term career goal to become an independent investigator conducting research that informs interventions to improve women’s sexual and reproductive health, including outcomes such as STI/HIV acquisition, fertility, and miscarriage. The three-year fellowship will allow Dr. Lokken to study how alterations in the vaginal microbiota may partly explain the increased risk of HIV acquisition among pregnant and postpartum women compared to non-pregnant women. Understanding the relationship between high-risk bacterial species and vaginal inflammation across the pregnancy and postpartum periods may inform the development of prevention strategies to reduce risks of reproductive health complications.
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August 19, 2019
Dr. Anjuli Wagner receives NIH K01 research and training grant to improve PrEP delivery for pregnant and postpartum women in Kenya
Categories: Awards, HIV, Research
Congratulations, Dr. Anjuli Wagner (Senior Fellow, Global Health) for receiving a National Institutes of Health (NIH) K01 grant, which supports early career researchers in gaining advanced research training and experience. Dr. Wagner’s new study, “Testing implementation strategies to improve delivery of PrEP for pregnant and postpartum women in Kenya,” aims to optimize the scaled-up delivery of PrEP—the daily oral pill to prevent HIV—in Kenya, where PrEP is systemically delivered in some regions during pregnancy. The grant allows Dr. Wagner an opportunity to complete her career development training in implementation science and health economics with strong mentorship and collaborations, and apply it within meaningful research to prevent maternal HIV acquisition in Kenya.
(more…)
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