2014

Esterbeg, R., Hailey, D.W., Rubel, E.W., Raible, D.W., ER–Mitochondrial Calcium Flow Underlies Vulnerability of Mechanosensory Hair Cells to Damage. Journal of Neuroscience, 33:9703–9719, 2014.pdf

Wang, Y., Sakano, H., Bebe, K., Brown, M.R., de Laat, R., Bothwell, M., Kulesza RJ Jr, Rubel EW. Intense and specialized dendritic localization of the fragile X mental retardation protein in binaural brainstem neurons -- a comparative study in the Alligator, Chicken, Gerbil, and Human. Journal of Comparative Neurology. 522:2107-2028.2014. pdf

Stawicki, TM., Owens, KN., Linbo, T., Reinhart, KE., Rubel, EW., Raible, DW. The zebrafish merovingian mutant reveals a role for pH regulation in hair cell toxicity and function. Disease Model Mechanisms. 2014, 7:847-856. pdf

2013

Coffin, A.B., Rubel, E.W., Raible, D.W. Bax, Bcl2, and p53 Differentially Regulate Neomycin- and Gentamicin-Induced Hair Cell Death in the Zebrafish Lateral Line. Journal of Associated Research in Otolaryngology. 2013, epub ahead of print. pdf

Schmitt, N.C., Rubel, E.W. Osteopontin Does Not Mitigate Cisplatin Ototoxicity or Nephrotoxicity in Adult Mice. Otolaryngology Head and Neck Surgery. 2013, epub ahead of print. pdf

Esterbeg, R., Hailey, D.W., Coffin, A.B., Raible, D.W., Rubel, E.W., Disruption of Intracellular Calcium Regulation is Integral to Aminoglycoside-Induced Hair Cell Death. Journal of Neuroscience, 33:7513-7525, 2013.pdf

Coffin, A.B., Williamson, K.L., Mamiya, A., Raible, D.W., Rubel, E.W. Profiling Drug Induced Cell Death Pathways in the Zebrafish Lateral Line. Apoptosis, 18:93-408, 2013.pdf

Thomas, A.J., Hailey, D.W., Stawicki, T.M. Wu, P., Coffin, A.B., Rubel, E.W., Raible, D.W, Simon, J.A., Ou, H.C. Functional Mechanotransduction is Required for Cisplatin-Induced Hair Cell Death in the Zebrafish Lateral Line. Journal of Neuroscience, 33:4405-4414. pdf

Mahrt, E.J., Perkel, D.J., Tong, L., Rubel, E.W., Portfors, C.V. Engineered Deafness Reveals that Mouse Courtship Vocalizations do not Require Auditory Experience. Journal of Neuroscience. 33:5573-5583, 2013. pdf

McBride, E.G., Rubel, E.W., Wang, Y. Afferent Regulation of Chicken Auditory Brainstem Neurons: Rapid Changes in Phosphorylation of Elongation Factor 2. Journal of Comparative Neurology, 521:1165-1183, 2013.pdf

Rubel, E.W., Furrer, S.A., Stone, J.S. A Brief History of Hair Cell Regeneration Research and Speculations on the Future. Hearing Research, 297: 42-51, 2013. pdf

Kashima, D.T., Rubel, E.W., Seidl, A.H. Pre-target Axon Sorting in the Avian Auditory Brainstem. Journal of Comparative Neurology, 521: 2310-2320. 2013 . pdf

Ou, H.C., Lin, V., Rubel, E.W. "In Bone" Utricle Cultures- a Simplified, Atraumatic Technique for in situ Cultures if the Adult Mouse (Mus musculus) Utricle. Otology & Neurology, 34:353-359, 2013.pdf

Seidl, A.H., Sanchez, J.T., Schecterson, L.C., Tabor, K.M., Wang, Y., Kashima, D.T., Poynter, G. Huss, D., Fraser, S.E., Lansforn, R., Rubel, E.W. Transgenic Quail as a Model for Research in the Avian Nervous System - a Comparative Study of the Auditory Brainstem. Journal of Comparative Neurology, 521:5-23, 2013.pdf

2012

McIlwain, S., Mathews, M., Bereman, M., Rubel, E.W., MacCoss, M.J., Noble, W.S. Estimating Relative Abundance of Proteins from Shotgun Proteomics Data. BMC Bioinformatics, 13:308, 2012.pdf

Ou, H.C., Keating, S., Wu, P., Simon, J.A., Raible, E.W. Quinoline Ring Derivatives Protect Against Aminoglycoside-Induced Hair Cell Death in the Zebrafish Lateral Line. Journal of the Association for Research in Otolaryngology, 13: 759- 770, 2012.pdf

Caras, M.L., O'Brien, M., Brenowitz, E.A., Rubel, E.W., Estradiol Selectivily Enhances Auditory Function in Avian Forebrain Neurons. Journal of Neuroscience, 32: 17597-17611, 2012.pdf

Hailey, D.W, Roberts, B., Owens, K.N., Stewart, A.K., Linbo, T., Pujol, R., Alper, S.L., Rubel, E.W., Raible, D.W. Loss Slc4a1b Chloride/Bicarbonate Exchanger Function Protects Mechanosensory Hair Cells from Aminoglycoside Damage in the Zebrafish Mutant Persephone. PLoS Genetics, 10:e1002971. PMC3569417. pdf

Golub, J.S., Tong, L., Nguyen, T.B., Hume, C.R., Palmiter, R.D., Rubel, E.W., Stone, J.S. Hair Cell Replacement in Adult Mouse Utricles After Target Ablation of Hair Cells with Diptheria Toxin. Journal of Neuroscience, 32:15093-15105, 2012.pdf

Schecterson, L.C., Sanchez, J.T., Rubel, E.W., Bothwell, M.A., TrkB Downregulation is Required for Dendrite Retraction in Developing Neurons of Chicken Nucleus Magnocellularis. Journal of Neuroscience. 32:14000-14009, 2012. pdf

Vlasits, A.L., Simon, J.A., Raible, D.W., Rubel, E.W., Owens, K. Screen of FDA-Approved Drug Library Reveals Compounds that Protect Hair Cells from Aminoglycosides and Cisplatin. Hearing Research, 294: 153-165, 2012.pdf

Esterberg, R., Coffin, A.B., Ou, H., Simon, J.A., Raible, D.W., Rubel, E.W. Fish in a Dish: Drug Discovery for Hearing Habilitation. Drug Discovery Today: Disease Models, 2012, In press.pdf

Sanchez, J.T., Seidl, A. H., Rubel, E.W., Barria, A. Control of Neuronal Excitability by NMDA-Rs in Early Developing Bunaural Auditory Neurons. Journal of Physiology, 590: 4801-4818, 2012. pdf

Wang, Y., and Rubel, E.W. In vivo Reversible Regulation of Dendritic Patterning by Afferent Input in Bipolar Auditory Neurons. Journal of Neuroscience. 32(33):11495–11504. pdf

Ou, H., Simon, J.A., Rubel, E.W., Raible, D.W. Screening for Chemicals that Affect Hair Cell Death and Survival in the Zebrafish Lateral Line. Hearing Research, 288:58-66, 2012.pdf

Tabor, K. M., Coleman, W.L., Rubel, E.W., Burger, R.M. Tonotopic Organization of the Superior Olivary Nucleus in the Chicken Auditory Brainstem. Journal of Comparative Neurology. 520: 1493–1508, 2012 . pdf

Namdaran, P., Reinhart, K.E., Owens, K.N., Raible, D.W., Rubel, E.W. Identification of Modulators of Hair Cell Regeneration in the Zebrafish Lateral Line. Journal of Neuroscience. 32(10):3516 –3528, 2012. PMC3318954. pdf

Suli, A., Watson, G., Rubel E.W., and Raible, D.W. Rheotaxis in Larval Zebrafish is Mediated by Lateral Line Mechanosensory Hair Cells. PLos One. 7:e29727, 2012. PMC3281009. pdf

2011

Sorensen, S.A., and,Rubel, E.W. Relative input strength rapidly regulates dendritic structure of chick nucleus laminaris neurons. Journal of Comparative Neurology, 519: 2838–2851, 2011. pdf

Burger, R.M., Fukui, I., Ohmori, H., and Rubel, E.W. Inhibition in the Balance: Binural Inhibitory Coupling in Sound Localization. Journal of Neurophysiology. 106: 4-14, 2011. pdf

Tabor, K.M., Wong, R.O.L., Rubel, E.W. Topography and morphology of the inhibitory projection from superior olivary nucleus to nucleus laminaris in chickens (gallus gallus). Journal of Comparative Neurology. 519: 358-375, 2011. pdf

2010

Wang, Y., Sanchez, J.T., and Rubel, E.W. Nucleus laminaris: In G. Shepherd D. D. Addona (Eds.), Handbook of brain microcircuits. New York, NY: Oxford University Press. In Press, 2010.

MacDonald, G., and Rubel, E.W. Three-dimensional confocal microscopy of the mamilian inner ear. Audiological Medicine. 8: 120-128, 2010. pdf

Fukui, I., Burger, R.M., Ohmori, H., and Rubel, E.W. GABAergic inhibition sharpens the frequency tuning and enhances phase locking in chicken nucleus magnocellularis neurons. Journal of Neuroscience. 30 (36):12075 - 83, 2010. pdf

Sanchez, J.T., Wang, Y., Rubel, E.W., and Barria, A. Development of glutamatergic synaptic transmission in binaural auditory neurons. Journal of Neurophysiology. 104:1774-89, 2010. pdf

Howard, M.A., and Rubel, E.W. Dynamic spike thresholds during synaptic integration preserve and enhance temporal response properties in the avian cochlear nucleus. Journal of Neuroscience. 30(36):12063-74, 2010. pdf

Coffin, A.B., Ou, H., Owens, K.N., Santos, F., Simon, J.A., Rubel, E.W., and Raible, D.W. Chemical screening for hair cell loss and protection in the zebrafish lateral line. Zebrafish. 7: 3-11, 2010. pdf

Ou, H., Santos, F., Raible, D.W., Simon, J.A., Rubel, E.W. Drug screening for hearing loss: using the zebrafish lateral line to screen for drugs that prevent and cause hearing loss. Drug Discovery Today. 15: 265-271, 2010. pdf

Caras, M.L., Brenowitz, E., and Rubel, E.W. Peripheral auditory processing changes seasonally in Gambel’s white-crowned sparrow. J Comp Physiol A. 196:581–599, 2010. pdf

Lentz, J., Cunningham, D.E., Robbins, C.A., Tempel, B.L., Bazan, N., Rubel, E.W.,Oesterle, E., and Bronya Keats, B. Deafness and retinal degeneration in a novel ush1c knock-in mouse model. J. Devel. Neurobiology. 70(4): 253-267, 2010. pdf

Seidl A.H., Rubel E.W., and Harris, D.M. Mechanisms for adjusting interaural time differences to achieve binaural coincidence detection. Journal of Neuroscience. 30(1):70 – 80, 2010. pdf

Seidl A.H., and Rubel E.W. A simple method for multiday imaging of slice cultures. Microsc Res Tech. 73:37-44, 2010. pdf

2009

Owens, K.N., Coffin, A.B., Raible, D.W., and Rubel, E.W. Zebrafish, a serendipitous solution. Hearing Health. 28-31, Summer, 2009. pdf

Seidl, A.H., Rubel, E.W. (Eds.) Auditory Neuroscience. Encyclopedia of Neuroscience. Springer: New York, 2009.

Owens, K.N., Coffin, A.B., Hong, L.S., O'Connell Bennett, K., Rubel, E.W., and Raible, D.W. Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways. Hearing Research. 253:32-41, 2009. pdf

Ou H.C, Cunningham L.L, Francis S.P., Brandon C.S., Simon J.A., Raible D.W., and Rubel E.W. Identification of FDA-approved drugs and bioactives that protect hair cells in the zebrafish (Danio rerio) lateral line and mouse (Mus musculus) utricle. J Assoc Res Otolaryngol. 10(2):191-203, 2009. pdf

Coffin, A.B., Reinhart, K.E., Owens, K.N., Raible, D.W., and Rubel, E.W. Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line. Hearing Research 253:42–51, 2009. pdf

Irvine, D.R.F., Brown, M., Kamke, M.R., and Rubel, E.W. Effects of restricted basilar papillar lesions and hair cell regeneration on auditory forebrain frequency organization in adult european starlings. Journal of Neuroscience 29(21):6871 –6882, 2009. pdf

Wang, Y., Cunningham, D.E., Tempel, B.L., and Rubel, E.W. Compartment-specific regulation of plasma membrane calcium ATPase type 2 in the chick auditory brainstem. Journal of Comparative Neurology 514:624–640, 2009. pdf

Schmitt, N.C., Rubel, E.W., and Nathanson, N.M. Cisplatin-induced hair cell death requires STAT1 and is attenuated by epigallocatechin gallate. Journal of Neuroscience 29(12):3843–3851, 2009. pdf

2008

Owens, K. N., Santos, F., Roberts, B., Linbo, T., Coffin, A. B., Knisely, A.J., Simon, J.A., Rubel, E.W., and Raible, D.W. Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death. PLoS Genetics. 2008, 4. pgen.1000020. pdf

Gorden, N.T., Arts, H.H., Parisi, M.A., Coene, K.L., Letteboer, S.J., van Beersum, S.E., Mans, D.A., Hikida, A., Eckert, M., Knutzen, D., Alswaid, A.F., Ozyurek, H., Dibooglu, S., Otto, E.A., Liu, Y., Davis, E.E., Hutter, C.M., Bammler, T.K., Farin, F.M., Dorschner, M., Topçu, M., Zackai, E.H., Rosenthal, P., Owens, K.N., Katsanis, N., Vincent, J.B., Hildebrandt, F., Rubel, E.W., Raible, D.W., Knoers, N.V., Chance, P.F., Roepman, R., Moens, C.B., Glass, I.A., Doherty, D. CC2D2A is mutated in Joubert syndrome and interacts with the ciliopathy-associated basal body protein CEP290. Am. J. Hum. Genet. 83: 559-571, 2008. pdf

Harris, J.A., Iguchi, F., Seidl, A. H., Lurie, D.I., Rubel, E.W.  Afferent deprivation elicits a transcriptional response associated with neuronal survival after a critical period in the mouse cochlear nucleus. Journal of Neuroscience 28(43):10990 –11002, 2008. pdf

MacDonald, G., and Rubel, E.W. Three-dimensional imaging of the intact mouse cochlea by fluorescent laser scanning confocal microscopy. Hearing Research 243:1-10, 2008. pdf

Chiu, L.L., Cunningham, L.L., Raible, D.W., Rubel, E.W, Ou, H.C. Using the zebrafish lateral line to screen for ototoxicity. JARO., 9:178-190, 2008. pdf

Wang, Y. and Rubel, E.W. Rapid regulation of microtubule-associated protein 2 in dendrites of nucleus laminaris of the chick following deprivation of afferent activity. Neuroscience 154:381–389, 2008. pdf

Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death.  Public Library of Sciences: Genetics. 4. pgen.1000020, 2008. pdf

Ma, E.Y., Rubel, E.W, Raible, D., W. Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line.Journal of Neuroscience 28: 2261-2273, 2008. pdf

Burger, R.M. and Rubel, E.W. Encoding of interaural timing for binaural hearing. In: A.I. Basbaum, A. Kaneko G. M. Shepherd, G. Westheimer, Eds. The Senses: A comprehensive Reference, Vol. 3, Audition P. Dallos and D. Oertel (Eds.). San Diego, Academic Press, 2008, 613-630. pdf

2007

Brenowitz, E., Lent, K., Rubel, E.W. Auditory feedback and song production do not regulate seasonal growth of song control circuits in adult white-crowned sparrows., Journal of Neuroscience, 2007, 27: 6810-6814. pdf

Ou, H.C., Raible, D.W, Rubel, E.W. Cisplatin-induced hair cell loss in zebrafish (Danio rerio) lateral line. Hearing Res., 2007, 233: 46–53. pdf

Howard, M.,  Burger, M.R., Rubel, E.W.  A developmental switch to GABAergic inhibition dependent on increases in Kv1-Type K+ Currents. Journal of Neuroscience, 2007, 27: 2112 - 2123. pdf

Owens, K.N, Cunningham D.E., MacDonald, G., Rubel, E.W., Raible D.W., Pujol R. Ultrastructural analysis of aminoglycoside-induced hair cell death in the zebrafish lateral line reveals an early mitochondrial response. J. Comp. Neurol., 2007, 502: 522-543. pdf

Lu Y., Harris J.A., Rubel E.W.  Development of spontaneous miniature EPSCs in mouse AVCN neurons over a critical period of afferent-dependent neuron survival. J. Neurophysiol., 2006, 97:635-46. pdf

2006

Harris J.A, Rubel E.W.  Afferent regulation of neuron number in the cochlear nucleus:  Cellular and molecular analyses of a critical period.
Hearing Research., 2006 , 216-217: 127-37. pdf

Sugahara K., Cunningham L.L., Rubel E.W.  Protection of adult vestibular hair cells against aminoglycoside toxicity by inhibition in the JNK signaling pathway, Hearing Research., 2006, 221: 128-135. pdf

Hendricks S.J., Rubel E.W, Nishi R.  Formation of the avian nucleus magnocellularis from the auditory anlage, J. Comp. Neurol., 2006, 498(4):  433-42. pdf

Sorensen S., Rubel E.W. The Level and Integrity of Synaptic Input Regulates Dendrite Structure, The Journal of Neuroscience,  2006, 1;26(5): 1539-50. pdf

Santos, F., MacDonald, G., Rubel, EW., Raible, D.W. Lateral line hair cell maturation is a determinant of aminoglycoside susceptibility in zebrafish (Danio rerio) . Hearing Research, 2006 , 213: 25-33. pdf

2005

Harris J., Hardie N., Bermingham-McDonogh, O., Rubel EW. Gene expression difference over a critical period of afferent-dependent neuron survival in the mouse auditory brainstem. J. Comparative Neurology, 2005 Dec 19; 493(3): 460-74. pdf

Cheng A., Cunningham L., Rubel EW. Mechanisms of hair cell death and protection. Curr Opin Otolaryngology Head and Neck Surgery. 2005 Dec; 13(6): 343-8. Review. pdf

Burger M., Pfeiffer J., Westrum L.E., Bernard A., and Rubel E.W. Expression of GABAB Receptor in the Avian Auditory Brainstem: Ontogeny, Afferent Deprivation, and Ultrastructure. J. Comp. Neurology, 2005, 489:11-22. pdf

Lu Y. and Rubel E.W. Activation of Metabotropic Glutamate Receptors Inhibits High-Voltage-Gated Calcium Channel Currents of Chicken Nucleus Magnocellularis Neurons , J. Neurophysiol., 2005, 93:1418-1428. pdf

Lu Y., Burger M., and Rubel E.W. GABAB Receptor Activation Modulates GABAA Receptor-Mediated Inhibition in Chicken Nucleus Magnocellularis Neurons, J. Neurophysiol., 2005, 93:1429-1438. pdf

Burger M., Cramer K., Pfeiffer J. and Rubel E.W. Avian Superior Olivary Nucleus Provides Divergent Inhibitory Input to Parallel Auditory Pathways. J. Comp. Neurology, 2005, 481:6-18. pdf

2004

Parks T.N., Rubel E.W., Fay R.R., and Popper A.N.(Eds). Plasticity of the Auditory System, Series: Springer Handbook of Auditory Research, Springer-Verlag: New York, Vol. 21, 2004. pdf

Rubel E.W, Parks T.N., and Zirpel L. Assembling, Connecting, and Maintaining the Cochlear Nucleus. In: Parks, T.N.; Rubel, E.W.; Popper, A.N.; Fay, R.R. (Eds.) Plasticity of the Auditory System, Series: Springer Handbook of Auditory Research, Springer-Verlag: New York, Vol. 21, 2004, pp 8 - 48. pdf

Person A.L., Cerretti D.P., Pasquale E.B., Rubel E.W, Cramer K.S. Tonotopic Gradients of Eph Family Proteins in the Chick Nucleus Laminaris During Synaptogenesis. J. Neurobiol., 2004, 60:28-39. pdf

Cunningham L., Matsui J.I., Warchol M.E., Rubel E.W. Overexpression of Bcl-2 Prevents Neomycin-Induced Hair Cell Death and Caspase-9 Activation in the Adult Mouse Utricle In Vivo. J. Neurobiol., 2004, 60:89-100. pdf

Lu Y., Monsivais, P., Tempel, B.L. and Rubel, E.W: Activity-Dependent Regulation of the Potassium Channel Subunits Kv1.1 and Kv3.1.
J. Comp Neurol., 2004, 470:93-106. pdf

Hirose, K, Westrum, L.D., Cunningham, D.E. and Rubel, E.W: Electron Microscopy of Degenerative Changes in the Chick Basilar Papilla Following Gentamicin Exposure. J. Comp. Neurol., 2004, 470:164-180. pdf

Cramer, K.S., Bermingham-McDonogh, O.M., Krull, C.E and Rubel E.W: EphA4 Restricts Axonal Connections To Individual Subcellular Elements. Devel. Biol., 2004, 269:26-35. pdf

Hardie, N.A., MacDonald, G. and Rubel, E.W: A New Method for Imaging and 3D Reconstruction of Mammalian Cochlea by Fluorescent Confocal Microscopy. Brain Res., 2004, 1000:200-210. pdf

Heydt, J.L., Cunningham, L.L., Rubel, E. W and Coltrera, M.D.: Round Window Gentamicin Application: An Inner Ear Hair Cell Damage Protocol for the Mouse. Hear. Res., 2004, 192:65-74. pdf

2003

Murakami ,S.L., Cunningham, L.L., Werner, L.A., Bauer, E., Pujol, R., Raible, D.W, and Rubel, E. W: Developmental Differences in Susceptibility to Neomycin-Induced Hair Cell Death in the Lateral Line Neuromasts of Zebrafish (Danio rerio). Hear. Res. 186:47-56, 2003. pdf

Molea, D. and Rubel, E.W: Timing and Topography of Nucleus Magnocellularis Innervation by the Cochlear Ganglion. J. Comp. Neurol. 466:577-591, 2003. pdf

Oesterle, E.C, Cunningham, D.E., Westrum, L.E. and Rubel, E.W: Ultrastructural Analysis of (3H)Thymidine-Labeled Cells in the Rat Utricular Macula. J Comp Neurol. 463:177-195, 2003. pdf

Harris, J.A., Cheng, A.G., Cunningham, L.L., Raible, D.W. and Rubel, E.W.: Neomycin-Induced Hair Cell Death and Rapid Regeneration in the Lateral Line of Zebrafish (Danio rerio): a Model System to Study Hair Cell Survival. JARO 04:219-234, 2003. pdf

Bermingham-McDonogh, O., and Rubel, E.W: Hair Cell Regeneration: Winging Our Way Towards a Sound Future. Curr Opin Neurobiol. 13:119-126, 2003. pdf

2002

Cheng A.G., Cunningham L.L., Rubel E.W.: Hair Cell Death in the Avian Basilar Papilla: Characterization of the in vitro Model and Caspase Activation. JARO. 4:91-105, 2002. pdf

Cramer, K.S., Karam, S. D., Bothwell, M., Cerretti, D.P., Pasquale, E.B. and Rubel, E.W.: Expression of EphB Receptors and EphrinB Ligands in the Developing Chick Auditory Brainstem. J. Comp. Neurol. 452:51-64, 2002. pdf

Cunningham, L.L., Cheng, A. G. and Rubel, E.W: Caspase activation in hair cells of the mouse utricle exposed to neomycin. J. Neurosci.: 22:8532-8540, 2002. pdf

Woolley, S.M.N. and Rubel, E.W: Vocal Memory and Learning in Adult Bengalese Finches with Regenerated Hair Cells. J. Neurosci. 22:7774-87, 2002. pdf

Rubel, E.W and Fritzsch, B.F.: Auditory System Development: Primary Auditory Neurons and Their Targets. Ann. Rev. Neurosci. 25:51-101, 2002. pdf

Mostafapour, S.P., del Puerto, N.M. and Rubel, E.W: bcl-2 overexpression eliminates deprivation-induced cell death of brainstem auditory neurons. J. Neurosci. 21:4670-4674, 2002. pdf

Rubel, E.W and Cramer, K.S.: Choosing Axonal Real Estate: Location, Location, Location. J. Comp. Neurol. 448:1-5, 2002. pdf

Gates, G.A., Mills, D.M., Nam, B-H, D'Angostino, R. and Rubel, E.W: Effects of Age on the Distortion-Product Otoacoustic Emission Growth Functions. Hear. Res. 163: 53-60, 2002. pdf

2001

Bermingham-McDonogh, O., Stone, J.S., Reh, T.A. and Rubel, E.W: FGFR3 Expression During Development and Regeneration of the Chick Inner Ear Sensory Epithelia. Dev. Bio. 238: 247-259, 2001. pdf

Monsivais, P. and Rubel, E.W: Accommodation enhances depolarizing inhibition in central neurons. J. Neurosci. 21:7823-7830, 2001. pdf

Pantelias, A.A., Monsivais, P., and Rubel, E.W: Tonotopic Map of Current and Voltage Responses of Chick Auditory Hair Cells. Hear. Res. 156:81-94, 2001. pdf

Woolley, S.M.N., Wissman, A.M. and Rubel, E.W: Hair cell regeneration and recovery of auditory thresholds following aminoglycoside ototoxicity in Bengalese finches. Hear. Res. 153:181-195, 2001. pdf

Goode, C.T., Maney, D.L., Rubel, E.W, and Fuchs, A.F.: Visual Influences on the Development and Recovery of the Vestibulo-Occular Reflex in the Chicken. J. Neurophysiol. 85:1119-1128, 2001. pdf

2000

Rubel, E.W: Try Riding a Horse. (Editorial). Am. J. Otology. 21:459-461, 2000.

Stone, J.S. and Rubel, E.W: Cellular Studies of Auditory Hair Cell Regeneration in Birds. Proc. Nat. Acad. Sci. 97:11714-11721, 2000. pdf

Mostafapour, S.P., Cochran, S.L., del Puerto, N.M., and Rubel, E.W: Patterns of Cell Death in Mouse AVCN Neurons After Unilateral Cochlea Removal, J. Comp. Neurol. 426:561-572, 2000. pdf

Cramer, K.S., Rosenberger, M.H., Frost, D.M., Cochran, S.L., Pasquale, E.B., and Rubel, E.W: Developmental Regulation of EphA4 Expression in the Chick Auditory Brainstem, J. Comp. Neurol. 426:270-278, 2000. pdf

Matsui, J.I., Oesterle, E.C., Stone, J.S., and Rubel, E.W: Characterization of Damage and Regeneration in Cultured Avian Utricles. JARO 1:46-63, 2000. pdf

Monsivais, P., Yang, L., and Rubel E.W: GABAergic Inhibition in Nucleus Magnocellularis: Implications for Binaural Processing in the Avian Brainstem. J. Neurosci. 20:2954-2963, 2000. pdf

Lurie, D.I., Solca, F., Fischer, E.H., and Rubel, E.W: Tyrosine Phosphatase SHP-1 Immunoreactivity Increases in Some Astrocytes Following Deafferentation of the Chicken Auditory Brainstem. J. Comp. Neurol. 421:199-214, 2000. pdf

Cramer, K.S., Fraser, S.E., and Rubel, E.W: Embryonic Origins of Auditory Brainstem Nuclei in the Chick Hindbrain. Dev. Biol. 224:138-151, 2000. pdf

Stone, J.S. and Rubel, E.W: Temporal, Spatial, and Morphological Features of Hair Cell Regeneration in the Avian Basilar Papilla. J. Comp. Neurol. 417:1-16, 2000. pdf

1999

Cochran, S.L., Stone, J.S., Bermingham-McDonogh, O., Akers, S.R., Lefcort, F., and Rubel, E.W: Ontogenetic Expression of Trk Neurotrophin Receptors in the Chick Auditory System. J. Comp. Neurol. 413:271-288, 1999. pdf

Stone, J.S., Choi, Y.S., Woolley, S.M.N., Yamashita, H., and Rubel, E.W: Progenitor Cell Cycling During Hair Cell Regeneration in the Vestibular and Auditory Epithelia of the Chick. J.Neurocytology 28:863-876, 1999. pdf

Hirose, K., Westrum, L.E., Stone, J.S., Zirpel, L., and Rubel, E.W: Dynamic Studies of Ototoxicity in Mature Avian Auditory Epithelium. "Ototoxicity: Basic Science and Clinical Applications", Ann. N. Y. Acad. Sci. 884:389-409, 1999. pdf

Mostafapour, S.P., Hockenbery, D.M., and Rubel, E.W: Life and Death in Otolaryngology: Mechanisms of Apoptosis and its Role in the Pathology and Treatment of Disease. Arch. Otolaryngol. HNS:729-737, 1999. pdf

Arts, H.A., Norton, S.J., and Rubel, E.W: The Effect of Perilymphatic Tetrodotoxin on Peripheral Auditory System Function. Sem. Hearing 20:3-12, 1999.

Kato, B.M. and Rubel, E.W: Glutamate Regulates IP3-Type and CICR Stores in the Avian Cochlear Nucleus. J. Neurophysiol. 81:1587-1596, 1999. pdf

Goode, C.T., Carey, J.P., Fuchs, A.F., and Rubel, E.W: Recovery of the Vestibulocolic Reflex After Aminoglycoside Ototoxicity in Domestic Chickens. J. Neurophysiol. 81:1025-1035, 1999. pdf

Löwenheim, H., Furness, D.N., Kil, J., Zinn, C., Gültig, K., Fero, M.L., Frost, D., Gummer, A.W., Roberts, J.M., Rubel, E.W, Hackney, C.M., and Zenner, H.-P.: Gene Disruption of p27Kip1 Allows Cell Proliferation in the Organ of Corti. PNAS 96:4084-4088, 1999. pdf

Stone, J.S. and Rubel, E.W: Delta 1 Expression During Avian Hair Cell Regeneration. Development 126:961-973, 1999. pdf

Molea, D., Stone, J.S., and Rubel, E.W: Class III -Tubulin Expression in Sensory and Nonsensory Regions of the Developing Avian Ear. J. Comp. Neurol. 406:183-198, 1999. pdf

Yang, L., Monsivais, P., and Rubel, E.W: The Superior Olivary Nucleus and its Influence on Nucleus laminaris: A Source of Inhibitory Feedback for Coincidence Detection in the Avian Auditory Brainstem. J. Neurosci. 19:2313-2325, 1999. pdf

Woolley, S.M.N. and Rubel, E.W: High Frequency Auditory Feedback is not Required for Adult Song Maintenance in Bengalese Finches. J. Neurosci. 19:358-371, 1999. pdf

1998

Rubel, E.W: Frontiers and Backwaters of Research on the Biological Bases of Hearing Development. Proceedings of the 135th Meeting of the Acoustical Society of America, Seattle, WA, 1998.

Mills, D.M. and Rubel, E.W: Development of Active and Passive Processes in the Gerbil Cochlea. Proceedings of the 135th Meeting of the Acoustical Society of America, Seattle, WA, 1998.

Mason, K., Peal, F.V., Jr., Stone, J.S., Rubel, E. W, and Bothwell, M.: Expression of Novel Potassium Channels in the Chick Basilar Papilla. Hearing Research 125:120-130, 1998. pdf

Lachica, E.A., Kato, B.M., Lippe, W.R., and Rubel, E.W: Glutamatergic and GABAergic Agonists Increase [Ca2+]i in Avian Cochlear Nucleus Neurons. J. Neurobiology 37:321-337, 1998. pdf

Mills, D.M. and Rubel, E.W: Development of the Base of the Cochlea: Place Code Shift in the Gerbil. Hearing Research 122:82-96, 1998. pdf

Konrad-Martin, D.L., Rübsamen, R., Dörrsheidt, G.J., and Rubel, E.W: Development of Single- and Two-Tone Responses of Anteroventral Cochlear Nucleus Neurons in Gerbil. Hearing Research 121:35-52, 1998. pdf

Marean, G.C., Burt, J.M., Beecher, M.D., and Rubel, E.W: Auditory Perception Following Hair Cell Regeneration in European Starling (Sturnus Vulgaris): Frequency and Temporal Resolution. J. Acoust. Soc. Am. 103:3567-3580, 1998.

Zirpel, L., Lippe, W.R., and Rubel, E.W: Activity-Dependent Regulation of Intracellular Calcium in Avian Cochlear Nucleus Neurons: Roles of Protein Kinases A and C and Relation to Cell Death. J. Neurophysiol. 79:2288-2302, 1998. pdf

Stone, J.S., Oesterle, E.C., and Rubel, E.W: Recent Insights Into Regeneration of Auditory and Vestibular Hair Cells. Cur. Opin. Neurol. 11:17-24, 1998.

1997

Kelley, M.S., Lurie, D.I., and Rubel, E.W: Rapid Regulation of Cytoskeletal Proteins and Their mRNAs Following Afferent Deprivation in the Avian Cochlear Nucleus. J. Comp. Neurol. 389:469-483, 1997. pdf

Mostafapour, S.P., Lachica, E.A., and Rubel, E.W: Mitochondrial Regulation of Calcium in the Avian Cochlear Nucleus. . J. Neurophysiol. 78:1928-1934, 1997. pdf

Mills, D.M., and Rubel, E.W: Changes in Cochlear Amplifier Mechanics During Development. In: Diversity in Auditory Mechanics. E.R. Lewis, G.R. long, R.F. Lyon, p.M. Narins, C.R. Steele and E. Hecht-Poinar (Eds.), World Sci. Press, Singapore, pp. 248-255, 1997.

Rubel, E.W, Popper, A.N., and Fay, R.R. (Eds.) Development of the Auditory System (Springer Handbook of Auditory Research, Volume 9). Springer-Verlag, New York, 1997.

Zirpel, L., Lachica, E.A., and Rubel., E.W: Afferent Regulation of Cochlear Nucleus Neurons. In: Neurotransmission and Hearing Loss: Basic Science, Diagnosis, and Management. Charles I. Berlin (Ed.), Singular Publishing Group, Inc., San Diego, CA, Chapter 3, pp. 47-76, 1997.

Woolley, S. and Rubel, E.W: Bengalese Finches Lonchura Striata domestica Depend Upon Auditory Feedback for the Maintenance of Adult Song. J. Neurosci. 17:6380-6390, 1997. pdf

Mills, D.M. and Rubel, E.W: Development of Distortion Product Emissions in the Gerbil: "Filter" Response and Signal Delay. J. Acoust. Soc. Am. 101:395-411, 1997.

Oesterle, E.C., Lurie, D.I., and Rubel, E.W: Neurofilament Proteins in Avian Auditory Hair Cells. J. Comp. Neurol. 379:603-616, 1997. pdf

Hirose, K., Hockenbery, D.M., and Rubel, E.W: Reactive Oxygen Species in Chick Hair Cells After Gentamicin Exposure In Vitro. Hearing Research 104:1-14, 1997. pdf

Lurie, D.I., Pasic, T.R., Hockfield, S.J., and Rubel, E.W: Development of CAT-301 Immunoreactivity in Auditory Brainstem Nuclei of the Gerbil. J. Comp. Neurol. 380:319-334, 1997. pdf

Oesterle, E.C., Tsue, T.T., and Rubel, E.W: Induction of Cell Proliferation in Avian Inner Ear Sensory Epithelia by Insulin-like Growth Factor-I and Insulin. J. Comp. Neurol. 380:262-274, 1997. pdf

Richards, T.L., Gates, G.A., Gardner, J.C., Merrill, T., Hayes, C.E., Panagiotides, H., Serafini, S., and Rubel, E.W: Functional Magnetic Resonance Spectroscopy of the Auditory Cortex in Patients with Sudden Sensorineural Hearing Loss. Amer. J. Neuroradiology 18:611-620, 1997. pdf

1996

Lachica, E.A., Zirpel, L., and Rubel, E.W: Intracellular Mechanisms Involved in the Afferent Regulation of Neurons in the Avian Cochlear Nucleus. In: Auditory System Plasticity and Regeneration. R.J. Salvi, D. Henderson, V. Colletti, & F. Fiorino, eds. Thieme Medical Publishers, Inc.:New York, 1996.

Tsue, T.T., Oesterle, E.C., and Rubel, E.W: In Vitro Analysis of Hair Cell Regeneration in the Avian Inner Ear. In: Auditory System Plasticity and Regeneration. R.J. Salvi, D. Henderson, V. Colletti, & F. Fiorino, eds. Thieme Medical Publishers, Inc.: New York, pp. 13-29, 1996.

Reyes, A.D., Rubel, E.W, and Spain, W.J.: In Vitro Analysis of Optimal Stimuli for Phase-Locking and Time-Delayed Modulation of Firing in Avian N. Laminaris Neurons. J. Neurosci. 16:993-1007, 1996. pdf

Mills, D.M. and Rubel, E.W: Development of the Cochlear Amplifier. J. Acoust. Soc. Am. 100:428-441, 1996.

Oesterle, E.C., and Rubel, E.W: Hair Cell Generation in Vestibular Sensory Receptor Epithelia. In: S.M. Highstein, B. Cohen, and J.A. Büttner-Ennever (Eds.) Annals New York Academy of Sciences: New Directions in Vestibular Research. New York Academy of Sciences: New York, pp. 34-46, 1996.

Carey, J., Fuchs, A.F., and Rubel, E.W: Hair Cell Regeneration and Vestibulo-Ocular Reflex Recovery. In: S.M. Highstein, B. Cohen, and J.A. Büttner-Ennever (Eds.) Annals New York Academy of Sciences: New Directions in Vestibular Research. New York Academy of Sciences: New York, pp. 47-58, 1996.

Kato, B.M., Lachica, E.A., and Rubel, E.W: Glutamate Modulates Intracellular Ca2+ Stores in Brainstem Auditory Neurons. J. Neurophysiol. 76:646-650, 1996.

Roberson, D.W., Kreig, C.S., and Rubel, E.W: Light Microscopic Evidence that Direct Transdifferentiation Gives Rise to New Hair Cells in Regenerating Avian Auditory Epithelium. Aud. Neurosci. 2:195-205, 1996.

Hartlage-Rübsamen, M. and Rubel E.W: Influence of Mitochondrial Protein Synthesis Inhibition on Deafferentation-Induced Ultrastructural Changes in Nucleus Magnocellularis of Developing Chicks. J. Comp. Neurol. 371:448-460, 1996. pdf

Stone, J.S., Leaño, S.G., Baker, L.P., and Rubel, E.W: Hair Cell Differentiation in the Chick Cochlear Epithelium Following Aminoglycoside Toxicity: In Vivo and In Vitro observations. J. Neurosci. 16:6157-6174, 1996. pdf

Rubel, E.W and Stone, J.S.: Stimulating Hair Cell Regeneration: On a Wing and a Prayer. Nature Med. 2:1082-1083, 1996.

Zirpel, L. and Rubel, E.W: Eighth Nerve Activity Regulates the Intracellular Calcium Concentration of Cochlear Nucleus Neurons in the Embryonic Chick via a Metabotopic Glutamate Receptor. J. of Neurophysiol. 76:4127-4139, 1996. pdf

Carey, J.P., Fuchs, A.F., and Rubel, E.W: Hair Cell Regeneration and Recovery of the Vestibulo-Ocular Reflex in the Avian Vestibular System. J. Neurophysiol. 76:3301-3312, 1996.

1995

Zirpel, L., Lachica, E.A., and Rubel, E.W: Activation of a Metabotropic Glutamate Receptor Increases Intracellular Calcium Concentrations in Neurons of the Avian Cochlear Nucleus. J. Neurosci. 15:214-222, 1995. pdf

Weisleder, P., Tsue, T.T., and Rubel, E.W: Hair Cell Replacement in Avian Vestibular Epithelium: Supporting Cell to Type I Hair Cell. Hearing Research 82:125-133, 1995. pdf

Marean, G.C., Cunningham, D., Burt, J.M., Beecher, M.D., and Rubel, E.W: Regenerated Hair Cells in the European Starling: Are they more Resistant to Kanamycin Ototoxicity than Original Hair Cells. Hearing Research 82:267-276, 1995. pdf

Rubel, E.W, Dew, L.A., and Roberson, D.W.: Mammalian Vestibular Hair Cell Regeneration. Science 267:701-703, 1995. pdf

Hyson, R.L. and Rubel, E.W: Activity-Dependent Regulation of a Ribosomal RNA Epitope in the Chick Cochlear Nucleus. Brain Research 672:196-204, 1995.

Lachica, E.A., Rübsamen, R., Zirpel, L., and Rubel, E.W: Glutamatergic Inhibition of Voltage Operated Calcium Channels in the Avian Cochlear Nucleus. J. Neurosci. 15:1724-1734, 1995. pdf

Hyson, R.L., Reyes, A.D., and Rubel, E.W: A Depolarizing Inhibitory Response to GABA in Brain Stem Auditory Neurons of the Chick. Brain Research 677:117-126, 1995.

Rübsamen, R., Mills, D.M., and Rubel, E.W: Effects of furosemide on distortion product otoacoustic emissions and on neuronal responses in the anteroventral cochlear nucleus. J. Neurophysiol. 74:1628-1638, 1995.

King, C., McGee, T., Rubel, E.W, Nicol, T., and Kraus, N.: Acoustic Features and Acoustic Change are Represented by Different Central Pathways. Hearing Research 85:45-52, 1995. pdf

Garden, G.A., Redeker-DeWulf, V.R., and Rubel, E.W: Afferent Influences on Brainstem Auditory Nuclei of the Chicken: Regulation of Transcriptional Activity Following Cochlea Removal. J. Comp. Neurol. 359:412-423, 1995.

Bhave, S.A., Stone, J.S., Rubel, E.W, and Coltrera, M.D.: Cell Cycle Progression in Gentamicin-damaged Avian Cochleas. J. Neurosci. 15:4618-4628, 1995. pdf

Hyde, G.E. and Rubel, E.W: Mitochondrial Role in Hair Cell Survival Following Injury. J. Oto-HNS 113:530-540, 1995. pdf

Garden, G.A., Hartlage-Rübsamen, M., and Rubel, E.W: Protein Masking of a Ribosomal RNA Epitope is an Early Event in Afferent Deprivation Induced Neuronal Death. Mol. Cell. Neurosci. 6:293-310, 1995. pdf

Roberson, D.W. and Rubel, E.W: Hair Cell Regeneration. Current Opinion in Otolaryngology 3:302-307, 1995.

Moore, D.R., Lippe, W.R., and Rubel, E.W: Effects of Middle Ear Pressure on Frequency Representation in the Central Auditory System. Hearing Research 89:93-100, 1995. pdf

Janas, J.D., Cotanche, D.A., and Rubel, E.W: Avian Cochlear Hair Cell Regeneration: Stereological Analyses of Damage and Recovery from a Single High Dose of Gentamicin. Hearing Research 92:17-29, 1995. pdf

1994

Roberson, D.W. and Rubel, E.W: Cell Division in the Gerbil Cochlea After Acoustic Trauma. Am. J. of Otology 15:28-34, 1994.

Rubel, E. W and Hyson, R. L., Afferent Influences on Brain Stem Auditory System Development. In: V. A. Casagrande and P.G. Shinkman, (Eds.), Advances in Neural and Behavioral Development, Vol. 4, Ablex, 37-68, 1994.

Tsue, T.T., Oesterle, E.C., and Rubel, E.W: Diffusible Factors Regulate Hair Cell Regeneration in the Avian Inner Ear. Proc. Nat. Acad. Sci. USA 91:1584-1588, 1994. pdf

Tsue, T.T., Watling, D.L., Weisleder, P., Coltrera, M.D., and Rubel, E.W: Identification of Hair Cell Progenitors and Intermitotic Migration of their Nuclei in the Normal and Regenerating Avian Inner Ear. J. Neurosci. 14:140-152, 1994. pdf

Wataya, H., Handa, K., Hozawa, K., Takasaka, T., Cunningham, D., Rubel, E.W, and Hakomori, S.: A characteristic protein specific to guinea pig inner ear, defined by monoclonal antibody WH-1. Hearing Research 72:254-262, 1994.

Garden, G.A., Canady, K.S., Lurie, D.I., Bothwell, M., and Rubel, E.W: A Biphasic Change in Ribosomal Conformation during Transneuronal Degeneration is Altered by Inhibition of Mitochondrial, but not Cytoplasmic Protein Synthesis. J. Neuroscience 14:1994-2008, 1994. pdf

Zirpel, L., Nathanson, N.M., Rubel, E.W, and Hyson, R.L.: Glutamate Stimulated Photidylinositol Metabolism in the Avian Cochlear Nucleus. Neuroscience Letters 168:163-166, 1994.

Lurie, D.I. and Rubel, E.W: Astrocyte Proliferation in the Chick Auditory Brainstem Following Cochlea Removal. J. Comp. Neurol. 346:276-288, 1994.

Tsue, T.T., Oesterle, E.C., and Rubel, E.W: Hair Cell Regeneration in the Inner Ear. J. Oto-HNS 111:281-301, 1994.

Tucci, D.L. and Rubel, E.W: Central Auditory System Development Disorders. In: Jackler, R.K. and Brackmann, D.E. (eds.), Textbook of Neurotology, Mosby Year Book, Inc., 567-617, 1994.

Reyes, A.D., Rubel, E.W, and Spain, W.J.: Membrane Properties Underlying the Firing of Neurons in the Avian Cochlear Nucleus. J. Neurosci. 14:5352-5364, 1994. pdf

Mills, D.M. and Rubel E.W: Variation of Distortion Product Otoacoustic Emissions with Furosemide Injection. Hearing Research 77:183-199, 1994.

Pasic, T.R., Moore, D.R., and Rubel E.W: The Effect of Altered Neuronal Activity on Cell Size in the Medial Nucleus of the Trapezoid Body and Ventral Cochlear Nucleus of the Gerbil. J. Comp. Neurol. 48:111-120, 1994.

Canady, K.S., Hyson, R.L., and Rubel, E.W: The Astrocytic Response to Afferent Activity Blockade in Chick Nucleus Magnocellularis is Independent of Synaptic Activation, Age and Neuronal Survival. J. Neurosci. 14:5973-5985, 1994. pdf

Lachica, E.A., Rübsamen, R., and Rubel, E.W: GABA-ergic Terminals in Nucleus Magnocellularis and Nucleus Laminaris Originate from the Superior Olivary Nucleus. J. Comp. Neurol. 348:403-418, 1994.

Solca, F.F., Lurie, D.I., Diltz, C.D., Johnson, R.S., Kumar, S., Rubel, E.W, and Fischer, E.H.: Identification and Purification of a Chicken Brain Neuroglia-associated Protein. J. Biol. Chem. 269:27559-27565, 1994. pdf

Canady, K.S., Olavarria, J.F., and Rubel, E.W: Reduced Retinal Activity Increases GFAP Immunoreactivity in Rat Lateral Geniculate Nucleus. Brain Research 663:206-214, 1994.

Mills, D.M., Norton, S.J., and Rubel, E.W: Development of Active and Passive Mechanics in the Mammalian Cochlea. Aud. Neurosci. 1:77-99, 1994.

1993

Durham, D., Matschinsky, F.M., and Rubel, E.W: Altered Malate Dehydrogenase Activity in Nucleus Magnocellularis of the Chicken Following Cochlea Removal. Hearing Research 70:151-159, 1993.

Duckert, L.G. and Rubel, E.W: Morphological Correlates of Functional Recovery in the Chicken Inner Ear After Gentamycin Treatment. J. Comp. Neurol. 331:75-96, 1993.

Weisleder, P. and Rubel, E.W: Hair Cell Regeneration Following Streptomycin Toxicity in the Avian Vestibular Epithelium. J. Comp. Neurol. 331:97-110, 1993.

Oesterle, E.C. and Rubel, E.W: Postnatal Production of Supporting Cells in the Chick Cochlea. Hearing Research 66:213-224, 1993.

Marean, G.C., Burt, J.M., Beecher, M.D., and Rubel, E.W: Hair Cell Regeneration in the European Starling (sturnus vulgaris): Recovery of Pure-Tone Detection Thresholds. Hearing Research 71:125-136, 1993.

Oesterle, E.C., Tsue, T.T., Reh, T.A., and Rubel, E.W: Hair-Cell Regeneration in Organ Cultures of the Postnatal Chicken Inner Ear. Hearing Research 70:85-108, 1993.

Duckert, L.G. and Rubel, E.W: Current Concepts in Hair Cell Regeneration. In: Otolaryngologic Clinics of North America, W.B. Saunders Co.: Philadelphia, 1993.

Steward, O. and Rubel, E.W: The Fate of Denervated Neurons: Transneuronal Degeneration, Dendritic Atrophy, and Dendritic Remodeling. In: A. Gorio (Ed.), Neuroregeneration, New York:Raven, 37-60, 1993.

Mills, D.M., Norton, S.J., and Rubel, E.W: Vulnerability and Adaptation of Distortion Product Otoacoustic Emissions to Endocochlear Potential Variation. J. Acoust. Soc. America 94:2108-2122, 1993.

1992

Sie, K.C.Y. and Rubel, E.W: Rapid Changes in Protein Synthesis and Cell Size in the Cochlear Nucleus following Eighth Nerve Activity Blockade and Cochlea Ablation. J. Comp. Neurol. 320:501-508, 1992. pdf

Rubel, E.W: Regeneration of Hair Cells in the Avian Inner Ear. In: A. Dancer, D. Henderson (Eds.) Noise-Induced Hearing Loss, Mosby-Year Book Inc., 204-227, 1992.

Overholt, E.M., Rubel, E.W, and Hyson, R.L.: A Circuit for Coding Interaural Time Differences in the Chick Brain Stem. J. Neurosci. 12, 1698-1708, 1992. pdf

von Bartheld, C.S. and Rubel, E.W: Paratympanic and Spiracular Sense Organs: Phylogenetic Distribution and Theories of Functions, Including Hearing. In: R.R. Fay, A.N. Popper, D.B. Webster (Eds.) Evolutionary Biology of Hearing, Springer, 582-583, 1992.

Oesterle, E.C., Cunningham, D.E., and Rubel, E.W: Utrastructure of Hyaline Border, and Cuboidal Cells in Chick Inner Ear. J. Comp. Neurol. 318:64-82, 1992. pdf

Roberson, D.F., Weisleder, P., Bohrer, P.S., and Rubel, E.W: Ongoing Production of Sensory Cells in the Vestibular Epithelium of the Chick. Hearing Research 57:166-174, 1992.

Weisleder, P. and Rubel E.W: Hair Cell Regeneration in the Avian Vestibular Epithelium. Experimental Neurology 115:2-6, 1992.

Canady, K.S. and Rubel, E.W: Rapid and Reversible Astrocytic Reaction to Afferent Activity Blockade in Chick Cochlear Nucleus. J. Neurosci. 12:1001-1009, 1992. pdf

Rubel, E.W and MacDonald, G.H.: Rapid Growth of Astrocytic Processes in N. Magnocellularis Following Cochlea Removal. J. Comp. Neurol. 318:415-425, 1992.

Lippe, W.R., Fuhrmann, D.S., Yang, W., and Rubel, E.W: Aberrant Projection Induced by Otocyst Removal Maintains Normal Tonotopic Organization in the Chick Cochlear Nucleus. J. Neurosci. 12:962-969, 1992. pdf

von Bartheld, C.S., Yang, W., and Rubel, E.W: Normal and Abnormal Pathfinding of Facial Nerve Fibers in the Chick Embryo. J. Neurobiology 23:1021-1036, 1992.

Werner, L.A. and Rubel, E.W (eds.): Developmental Psychoacoustics. Washington, D.C.:American Psychological Association, 1992.

Donaldson, J.A., Duckert, L.G., Lambert, P.M., and Rubel, E.W: AnsonoDonaldson Surgical Anatomy of the Temporal Bone (Fourth Edition). New York:Raven Press, 1992.

1991

Norton, S.J., Bargones, J.Y., and Rubel, E.W: Development of Otoacoustic Emissions in Gerbil: Evidence for Micromechanical Changes Underlying Development of the Place Code. Hearing Research 51:73-92, 1991.

Girod, D.A., Tucci, D.L., and Rubel, E.W: Anatomical Correlates of Functional Recovery in the Avian Inner Ear Following Aminoglycoside Ototoxicity. Laryngoscope 101:1139-1149, 1991.

Santos, P.M., Winterowd, J.G., Allan, G.G., Bothwell, M.A., and Rubel, E.W: Nerve Growth Factor: Increased Angiogenesis without Improved Nerve Regeneration. J. Oto-HNS 105:12-25, 1991.

Hyson, R.L. and Rubel, E.W: Methods for Studying Experiential Influences on Brain Development. In: H.N. Shair, G.A. Barr, and M.A. Hofer (Eds.), Developmental Psychobiology: New Methods and Changing Concepts, Oxford University Press, pp 241-255, 1991.

Ryals, B.M., Rubel, E.W, and Lippe W.R.: Issues in Neural Plasticity as Related to Cochlear Implants in Children. Am. J. of Otology 12:22-27, 1991.

Pasic, T.R. and Rubel, E.W: Cochlear Nucleus Cell Size is Regulated by Auditory Nerve Electrical Activity. J. Oto-HNS 104:6-13, 1991.

Girod, D.A. and Rubel, E.W: Hair Cell Regeneration in the Avian Cochlea. If it works in birds, why not in man? Ear, Nose, and Throat J. 70:343-354, 1991.

Born, D.E., Durham, D., and Rubel, E.W: Afferent Influences on Brainstem Auditory Nuclei of the Chick: Nucleus Magnocellularis Neuronal Activity Following Cochlea Removal. Brain Research 557:37-47, 1991.

Garden, G.A., Bothwell, M. and Rubel, E.W: Lack of Correspondence Between mRNA Expression for a Putative Cell Death Molecule (SGP-2) and Neuronal Cell Death in the Central Nervous System. J. Neurobiol. 22:590-604, 1991.

Adams, L., Norton, S.J., Weisleder, P., Rubel, E.W, and Tempel, B: Deaf Waddler Mouse. Hereditary Deafness Newsletter No. 6, April, 1991.

Rubel, E.W, Oesterle, E.C., and Weisleder, P.: Hair Cell Regeneration in the Avian Inner Ear. Ciba Foundation Symposium, Regeneration of Vertebrate Sensory Receptor Cells, John Wiley and Sons, pp. 77-96, 1991.

Rubel, E.W, Falk, P.M., Canady, K.S., and Steward, O.: A Cellular mechanism Underlying Activity-Dependent Transneuronal Degeneration: Rapid but Reversible Destruction of Neuronal Ribosomes. Brain Dysfunction 4:55-74, 1991.

von Bartheld, C.S., Patterson, S.L., Heuer, J.G., Wheeler, E.F., Bothwell, M., and Rubel, E.W: Expression of Nerve Growth Factor (NGF) Receptors in the Developing Inner Ear of Chick and Rat. Development 113:455-470, 1991.

1990

Von Bartheld, C.S., Cunningham, D.E., and Rubel, E.W: Neuronal Tracing with DiI: decalcification, cryosectioning, and photoconversion for light and electron microscopic analysis. J. Histochem and Cytochem. 38:725-733, 1990.

Rubel, E.W, Hyson, R.L., and Durham, D.: Afferent Regulation of Neurons in the Brain Stem Auditory System. J. Neurobiol. 21:169-196, 1990.

Oesterle, E.C., Sarthy, P.V., ander, P. and Rubel, E.W: Reversible Blockade of Vestibular Evoked Activity in the Chick. Hearing Research 47:257-262, 1990.

Code, R.A., Durham, D., and Rubel, E.W: Effects of Cochlea Removal on GABAergic Terminals in Nucleus Magnocellularis of the Chicken. J. Comp. Neurol. 301:643-654, 1990.

1989

Duckert, L.G. and Rubel, E.W: Ultrastructural Observations on Regenerating Hair Cells in the Chick Basilar Papilla. Hearing Researc Steiner (Eds.) Textbook of Physiology, W.B. Saunders: Philadelphia, pp. 386-411, 1989.

Deitch, J.S. and Rubel, E.W: Rapid Changes in Ultrastructure During Deafferentation-Induced Dendritic Atrophy. J. Comp. Neurol. 281:234-258, 1989.

Deitch, J.S. and Rubel, E.W: Changes in Neuronal Cell Bodies in N. Laminaris During Deafferentation-Induced Dendritic Atrophy. J. Comp. Neurol. 281:259-268, 1989.

Hashisaki, G.T. and Rubel, E.W: Effects of Unilateral Cochlea Removal on Anteroventral Cochlear Nucleus Neurons in Developing Gerbils. J. Comp. Neurol. 283:465-473, 1989.

Pasic, T.R. and Rubel, E.W: Rapid Changes in Cochlear Nucleus Cell Size Following Blockade of Auditory Nerve Electrical Activity in Gerbils. J. Comp. Neurol. 283:474-480, 1989. pdf

Code, R.A., Burd, G.D., and Rubel, E.W: Development of GABA Immunoreactivity in Brainstem Auditory Nuclei of the Chick: Ontogeny of Gradients in Terminal Staining. J. Comp. Neurol. 284:504-518, 1989.

Von Bartheld, C.S. and Rubel, E.W: Transient GABA Immunoreactivity in Cranial Nerves of the Chick Embryo. J. Comp. Neurol. 286:456-471, 1989.

Hyson, R.L. and Rubel, E.W: Transneuronal Regulation of Protein Synthesis in the Brain Stem Auditory System of the Chick Requires Synaptic Activation. J. Neurosci. 9:2835-2845, 1989. pdf

Code, R.A. and Rubel, E.W: Glycine-Immunoreactivity in the Auditory Brain Stem of the Chick. Hearing Res. 40:167-172, 1989.

Von Bartheld, C.S., Code, R.A., and Rubel, E.W: GABAergic Neurons in Brainstem Auditory Nuclei of the Chick: Distribution, Morphology, and Connectivity. J. Comp. Neurol. 287:470-483, 1989.

Girod, D.A., Duckert, L.G., and Rubel, E.W: Possible Precursors of Regenerated Hair Cells in the Avian Cochlea Following Acoustic Trauma. Hearing Res. 42:175-194, 1989. pdf

Durham, D. , Rubel, E.W, and Steel, K.: Cochlear ablation in deafness mutant mice: 2-deoxyglucose analysis suggests no spontaneous activity of cochlear origin. Hearing Res. 43:39-46, 1989.

Weisleder, P., Jones, T.A., and Rubel, E.W: Potenciales Evocados Vestibulares en Gallus Domesticus. Archivos de Neurobiologia 52:307-313, 1989 .

1988

Sanes, D.H. and Rubel, E.W: The Ontogeny of Inhibition and Excitation in the Gerbil Lateral Superior Olive. J. Neurosci. 8:682-700, 1988. pdf

Born, D.E. and Rubel, E.W: Afferent Influence on Brain Stem Auditory Nuclei of the Chicken: Presynaptic Action Potentials Regulate Protein Synthesis in Nucleus Magnocellularis Neurons. J. Neurosci. 8:901-919, 1988. pdf

Ryals, B.M. and Rubel, E.W: Hair Cell Regeneration after Acoustic Trauma in Adult Coturnix Quail. Science 240:1774-1776, 1988. pdf

Rubel, E.W and Parks, T.N.: Organization and Development of the Avian Brain-Stem Auditory System. In: G.M. Edelman, W.E. Gall and W. M. Cowan (Eds.), Auditory Function: Neurobiological Bases of Hearing. John Wiley, pp. 3-92, 1988.

Flint, P., Duckert, L.G., Dobie R.A., and Rubel, E.W: Chronic Perilymphatic Fistula. Otolaryngol. Head Neck Surg. 99:380-388, 1988.

Sanes, D.H. and Rubel, E.W: The Development of Stimulus Coding in the Auditory System. In: A.F. Jahn and J.R. Santos-Sacchi (Eds.), Physiology of the Ear. Raven Press, New York, pp. 431-455, 1988.
 

1987

Tucci, D.L., Born, D.E., and Rubel, E.W: Changes in Spontaneous Activity and CNS Morphology Associated with Conductive and Sensorineural Hearing Loss in Chickens. Ann. Otol. Rhinol. Laryngol. 96:343-350, 1987.

Born, D.E., Carman, C.S. and Rubel, E.W: Correcting Errors in Estimating Neuron Area Caused by the Position of the Nucleolus. J. Comp. Neurol. 255:146-152, 1987.

Sanes, D.H., Geary, W.A., Wooten, G.F., and Rubel, E.W: Quantitative Distribution of the Glycine Receptor in the Auditory Brain Stem of the Gerbil. J. Neurosci. 7:3793-3802, 1987. pdf

Cruz, R.M., Lambert, P.R., and Rubel, E.W: Light Microscopic Evidence of Hair Cell Regeneration after Gentamicin Toxicity in Chick Cochlea. Arch. Otolaryngol. Head Neck Surg. 113:1058-1062, 1987. pdf
 

1986

Ruben, R.J., van de Water, T.R. and Rubel, E.W (Eds.): The Biology of Change in Otolaryngology. Excerpta Medica: Amsterdam, Netherlands, 1986.

Lambert, P.R., Palmer, P., and Rubel, E.W: The Interaction of Noise and Aspirin in the Chick Basilar Papilla. Arch. Otolaryngol. Head Neck Surg. 112:1043-1049, 1986.

Lippe, W.R., Ryals, B.M., and Rubel, E.W: Development of Place Principle. In: R.N. Aslin (Ed.), Advances in Neural and Behavioral Development. Ablex Pub. Co: Norwood, NJ, pp. 155-203, 1986.

Young, S.R. and Rubel, E.W: Embryogenesis of Arborization Pattern and Topography of Individual Axons in N. Laminaris of the Chicken Brain Stem. J. Comp. Neurol. 254:425-459, 1986. pdf

1985

Rubel, E.W: Strategies and Problems for Future Studies of Auditory Development. Acta Otolaryngol. 421:114-128, 1985.

Gray, L. and Rubel, E.W: Development of Absolute Thresholds in Chickens. J. Acoust. Soc. Am. 77:1162-1172, 1985. pdf

Born, D.E. and Rubel, E.W: Afferent Influences on Brain Stem Auditory Nuclei of the Chicken: Neuron Number and Size Following Cochlea Removal. J. Comp. Neurol. 231:435-445, 1985. pdf

Durham, D. and Rubel, E.W: Afferent Influences on Brain Stem Auditory Nuclei of the Chicken: Changes in Succinate Dehydrogenase Activity Following Cochlea Removal. J. Comp. Neurol. 231:446-456, 1985.

Steward, O. and Rubel, E.W: Afferent Influences on Brain Stem Auditory Nuclei of the Chicken: Cessation of Amino Acid Incorporation as an Antecedent to Age-Dependent Transneuronal Degeneration. J. Comp. Neurol. 231:385-395, 1985.

Severns, M., Gray, L., and Rubel, E.W: An Avian Vocalization Detector. Physiol. Behav. 34:843-845, 1985. pdf

Mattox, D.E., Olmos, D.R., and Rubel, E.W: Freeze-fracture of Neurons in Nucleus Magnocellularis of the Chick. Hearing Res. 17:67-78, 1985.

Lippe, W.R. and Rubel, E.W: Ontogeny of Tonotopic Organization of Brain Stem Auditory Nuclei in the Chicken: Implications for Development of the Place Principle. J. Comp. Neurol. 237:273-289, 1985.

Tucci, D.L. and Rubel, E.W: Afferent Influences on Brain Stem Auditory Nuclei of the Chicken: Effects of Conductive and Sensorineural Hearing Loss on N. magnocellularis. J. Comp. Neurol. 238:371-381, 1985.

Ryals, B.M. and Rubel, E.W: Differential Susceptibility of Avian Hair Cells to Acoustic Trauma. Hearing Res. 19:73-84, 1985.

Ryals, B.M. and Rubel, E.W: Ontogenetic Changes in the Position of Hair Cell Loss after Acoustic Overstimulation in Avian Basilar Papilla. Hearing Res. 19:135-142, 1985.

1984

Rubel, E.W, Ryals, B.M., and Lippe, W.R.: Development of the Place Principle. J. Acoust. Soc. Am. 75:635, 1984.

Rubel, E.W: Ontogeny of Auditory System Function. In: R.M. Berne (Ed.). Annual Review of Physiology 46:213-229, 1984.

Rubel, E.W (Section Ed.): Advances in the Physiology of Auditory Information Processing, Special invited section. Annu. Rev. Physiol. 46: 1984.

Rubel, E.W: Auditory System Development. In: N.A. Krasnegor and G. Gottlieb (Eds.), Measurement of Audition and Vision During the First Year of Life: A Methodological Overview, pp. 53-86, 1984.

Gray, L. and Rubel, E.W: Development of Auditory Thresholds and Frequency Difference Limens in Chicks. in: N.A. Krasnegor and G. Gottlieb (Eds.), Measurement of Audition and Vision During the First Year of Life: A Methodological Overview, pp. 145-165, 1984.

Rubel, E.W, Born, D.E., Deitch, J.S., and Durham, D.: Recent Advances Toward Understanding Auditory System Development. In: C. Berlin (Ed.), Hearing Science, Chapter 3, pp. 109-157, 1984.

Deitch, J.S. and Rubel, E.W: Afferent Influences on Brain Stem Auditory Nuclei of the Chicken: Time Course and Specificity of Dendritic Atrophy Following Deafferentation. J. Comp. Neurol. 229:66-79, 1984.

Rubel, E.W, Lippe, W.R., and Ryals, B.M.: Development of the Place Principle. Ann. Otol. Rhinol. Laryngol. 93(6):609-615, 1984.

Ryals, B.M., Creech, H.B. and Rubel, E.W: Postnatal Changes in the Size of the Avian Cochlear Duct. Acta Otolaryngol. 98:93-97, 1984.

1983

Rubel, E.W and Ryals, B.M.: Development of the Place Principle: Acoustic Trauma. Science 219:512-514, 1983. pdf

Lippe, W. and Rubel, E.W: Development of the Place Principle: Tonotopic Organization. Science 219:514-516, 1983. pdf

Smith, Z.D.J., Gray, L., and Rubel, E.W: Afferent Influences on Brain Stem Auditory Nuclei of the Chicken: N. laminaris Dendritic Length Following Monaural Conductive Hearing Loss. J. Comp. Neurol. 220:199-205, 1983.

Young, S. and Rubel, E.W: Frequency-Specific Projections of Individual Neurons in Chick Brain Stem Auditory Nuclei. J. Neurosci. 7:1373-1378, 1983. pdf

1982

Ryals, B.M. and Rubel, E.W: Patterns of Hair Cell Loss in Chick Basilar Papilla after Intense Auditory Stimulation: Frequency Organization. Acta Otolaryngol. 93:205-210, 1982.

Rubel, E.W and Ryals, B.M.: Patterns of Hair Cell Loss in Chick Basilar Papilla after Intense Auditory Stimulation: Exposure Duration and Survival Time. Acta Otolaryngol. 93:31-41, 1982.

Hackett, J.T., Jackson, H., and Rubel, E.W: Synaptic Excitation of the Second and Third Order Auditory Neurons in the Avian Brain Stem. Neuroscience 7:1455-1469, 1982.

Gray, L., Smith, Z., and Rubel, E.W: Development and Experiential Changes in Dendritic Symmetry. Brain Res. 244:360-364, 1982.

Jackson, H., Hackett, J.T., and Rubel, E.W: Organization and Development of Brain Stem Auditory Nuclei in the Chick: Ontogeny of Postsynaptic Responses. J. Comp. Neurol. 210:80-86, 1982.

Rebillard, G., Ryals, B.M., and Rubel, E.W: Relationship Between Hair Cell Loss on the Chick Basilar Papilla and Threshold Shift After Acoustic Overstimulation. Hearing Res. 8:77-81, 1982.

1981

Rubel, E.W, Smith, Z.D.J., and Steward, O.: Sprouting in the Avian Brain Stem Auditory Pathway: Dependence on Dendritic Integrity. J. Comp. Neurol. 202:397-414, 1981.

Gray, L. and Rubel, E.W: Development of Responsiveness to Suprathreshold Acoustic Stimulation in Chickens. J. Comp. Physiol. Psychol. 95:188-198, 1981. pdf

Rubel, E.W: Pathophysiology of Hearing Loss: Functional Anatomy. In: G. Gates (Ed.), Clinical Auditory Evaluation. American Academy of Otolaryngology: Rochester, Minnesota, pp. 18-22, 1981.

Rebillard, G. and Rubel, E.W: Electrophysiological Study of Maturation of Auditory Responses from the Inner Ear of the Chick. Brain Res. 229:15-23, 1981.

1980

Lippe, W.R., Steward, O., and Rubel, E.W: The Effect of Unilateral Basilar Papilla Removal upon Nuclei Laminaris and Magnocellularis of the Chick Examined with [3H] 2-Deoxy-D-Glucose Autoradiography. Brain Res. 196:45-58, 1980.

Rubel, E.W, Parks, T.N., Smith, D.J., and Jackson, H.: Experiential Afferent Influences and Development in the Avian N. magnocellularis and N. laminaris. Proc. XVII International Congress of Ornithology, 701-709, 1980.

1979

Kerr, L.M., Ostapoff, E.M., and Rubel, E.W: The Influence of Acoustic Experience on the Ontogeny of Frequency Generalization Gradients in the Chicken. J. Exp. Psychol. (Anim. Behav. 5:97-115, 1979. pdf

Smith, D.J. and Rubel, E.W: Organization and Development of Brain Stem Auditory Nuclei of the Chicken: Dendritic Gradients in Nucleus laminaris. J. Comp. Neurol. 186:213-240, 1979. pdf

Jahrsdoerfer, R.S., Feldman, P.S., Rubel, E.W, Guerrant, J.L., Eggleston, P.A., and Selden, R.F.: Otitis Media and the Immotile Cilia Syndrome. Laryngoscope 5:769-777, 1979.

1978

Rubel, E.W: Ontogeny of Structure and Function in the Vertebrate Auditory System. In: Handbook of Sensory Physiology, Vol. IX, Development of Sensory Systems. M. Jacobson (Ed.),. Springer-Verlag, Chapter 5, pp. 135-237, 1978. pdf

Jackson, H. and Rubel, E.W: Ontogeny of Behavioral Responsiveness to Sound in the Chick Embryo as Indicated by Electrical Recordings of Motility. J. Comp. Physiol. Psychol. 92:682-696, 1978.

Parks, T.N. and Rubel, E.W: Organization and Development of the Brain Stem Auditory Nuclei of the Chicken: Primary Afferent Projections. J. Comp. Neurol. 180:439-448, 1978. pdf

Parks T.N. and Rubel, E.W: An anatomic "place" model of low-frequency sound localization. Otolaryngology 86:ORL-785, 1978.

1977

Benes, F.M., Parks, T.N., and Rubel, E.W: Rapid Dendritic Atrophy Following Deafferentation: An EM Morphometric Analysis. Brain Res. 122:1-13, 1977. pdf

1976

Rubel, E.W, Smith, D.J., and Miller, L.C.: Organization and Development of Brain Stem Auditory Nuclei of the Chicken: Ontogeny of N. magnocellularis and N. laminaris. J. Comp. Neurol. 166:469-490, 1976. pdf

1975

Rubel, E.W and Rosenthal, M.: The Ontogeny of Auditory Frequency Generalization in the Chicken. J. Exp. Psychol. (Anim. Behav.) 1:287-297, 1975.

Rubel, E.W and Parks, T.N.: Organization and Development of Brain Stem Auditory Nuclei of the Chicken: Tonotopic Organization of N. magnocellularis and N. laminaris. J. Comp. Neurol 164:411-434, 1975. pdf

Parks, T.N. and Rubel, E.W: Organization and Development of Brain Stem Auditory Nuclei of the Chicken: Organization of Projections from N. magnocellularis to N. laminaris. J. Comp. Neurol. 164:435-448, 1975. pdf

Thompson, R.F. and Rubel, E.W: Evolution and Behavior. In: R.F. Thompson, Introduction to Physiological Psychology, Harper and Row: New York, Chapter 1, pp. 5-30, 1975.

Thompson, R.F. and Rubel, E.W: Genetic and Development Bases of Behavior. In: R.F. Thompson, Introduction to Physiological Psychology, Harper and Row: New York, Chapter 2, pp. 31-64, 1975.

1974

Johnson, J.E., Rubel, E.W, and Hatton, G.E.: Mechanosensory Projections to Cerebral Cortex of Sheep. J. Comp. Neurol. 158:81-108, 1974.

1971

Rubel, E.W: A Comparison of Somatotopic Organization in Sensory Neocortex of Newborn Kittens and Adult Cats. J. Comp. Neurol. 143:447-480, 1971.

Rubel, E.W: Man's Animals. Contemp. Psychol. 16:502-503, 1971.

Mayers, K.S., Robertson, R.T., Rubel, E.W, and Thompson, R.F.: Development of Polysensory Responses in Association Cortex of Kitten. Science 171:1038-1040, 1971. pdf

1970

Rubel, E.W: Effects of Early Experience on Fear Behavior of Coturnix coturnix. Animal Behav. 18:427-433, 1970. pdf

Rubel, E.W: Opossum Atlas. Contemp. Psychol. 15:582, 1970.

1968

Raskin, D.C., Boice, C., Rubel, E.W and Clark, D.: Transfer Tests of the Frequency Theory of Verbal Discrimination Learning. J. Exper. Psychol. 76:521-529, 1968.

1967

Raskin, D.C., Hattle, M. and Rubel, E.W: The Effects of Electric Shock Isolation in Serial Learning. Psychonomic Sci. 8:413-414, 1967.