Publications

For links to PubMed Citations, please view our complete list of publications here.

 

PMIDAuthorsTitleJournal
8029509Merjaneh L, Toprak D, McNamara S, Nay L, Sullivan E, Rosefeld M.Acute hyperglycaemia in cystic fibrosis pulmonary exacerbations.Endocrinol Diabetes Metab. 2021
33715993Franz N, Rapp H, Hansen RN, Gold LS, Goss CH, Lechtzin N, Kessler LG.Health care costs related to home spirometry in the eICE randomized trial.J Cyst Fibros. 2021
33685776VanDevanter EJ, Heltshe SL, Skalland M, Lechtzin N, Nichols D, Goss CH.The effect of oral and intravenous antimicrobials on pulmonary exacerbation recovery in cystic fibrosis.J Cyst Fibros. 2021
33664232Phuong MS, Hernandez RE, Wolter DJ, Hoffman LR, Sad S.Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response.Cell Death Dis. 2021
33573995Zemanick ET, Konstan MW, VanDevanter DR, Rowe SM, Clancy JP, Odem-Davis K, Skalland M, Mayer-Hamblett N.Measuring the impact of CFTR modulation on sweat chloride in cystic fibrosis: Rationale and design of the CHEC-SC study.J Cyst Fibros. 2021
33448264de Moraes MH, Hsu F, Huang D, Bosch DE, Zeng J, Radey MC, Simon N, Ledvina HE, Frick JP, Wiggins PA, Peterson SB, Mougous JD.An interbacterial DNA deaminase toxin directly mutagenizes surviving target populations.Elife. 2021
33390317Pope CE, Vo AT, Hayden HS, Weiss EJ, Durfey S, McNamara S, Ratjen A, Grogan B, Carter S, Nay L, Parsek MR, Singh PK, McKone EF, Aitken ML, Rosenfeld MR, Hoffman LR.Changes in fecal microbiota with CFTR modulator therapy: A pilot study.J Cyst Fibros. 2020
33386232Stephenson AL, Ramos KJ, Sykes J, Ma X, Stanojevic S, Quon BS, Marshall BC, Petren K, Ostrenga JS, Fink AK, Faro A, Elbert A, Chaparro C, Goss CH.Bridging the survival gap in cystic fibrosis: An investigation of lung transplant outcomes in Canada and the United States.J Heart Lung Transplant. 2020
33349583Pearson K, Mayer-Hamblett N, Goss CH, Retsch-Bogart GZ, VanDalfsen JM, Burks P, Rosenbluth D, Clancy JP, Hoffman A, Nichols DP.The impact of SARS-CoV-2 on the cystic fibrosis foundation therapeutics development network.J Cyst Fibros. 2021
33313307Goss CH, Jain R, Seibold W, Picard AC, Hsu MC, Gupta A, Fajac I.An innovative phase II trial to establish proof of efficacy and optimal dose of a new inhaled epithelial sodium channel inhibitor BI 1265162 in adults and adolescents with cystic fibrosis: BALANCE-CFTM 1.ERJ Open Res. 2020
33296701Rodda LB, Netland J, Shehata L, Pruner KB, Morawski PA, Thouvenel CD, Takehara KK, Eggenberger J, Hemann EA, Waterman HR, Fahning ML, Chen Y, Hale M, Rathe J, Stokes C, Wrenn S, Fiala B, Carter L, Hamerman JA, King NP, Gale M Jr, Campbell DJ, Rawlings DJ, Pepper M.Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.Cell. 2021
33296290Long DR, Wolter DJ, Lee M, Precit M, McLean K, Holmes E, Penewit K, Waalkes A, Hoffman LR, Salipante SJ.Polyclonality, Shared Strains, and Convergent Evolution in Chronic CF S. aureus Airway Infection.Am J Respir Crit Care Med. 2020
33259594Wolter DJ, Scott A, Armbruster CR, Whittington D, Edgar JS, Qin X, Buccat AM, McNamara S, Blackledge M, Waalkes A, Salipante SJ, Ernst RK, Hoffman LR.Repeated isolation of an antibiotic-dependent and temperature-sensitive mutant of Pseudomonas aeruginosa from a cystic fibrosis patient.J Antimicrob Chemother. 2021
33246911Magaret AS, Salerno J, Deen JF, Kloster M, Mayer-Hamblett N, Ramsey BW, Nichols DP.Long-term azithromycin use is not associated with QT prolongation in children with cystic fibrosis.
33137262Jorth P, Durfey S, Rezayat A, Garudathri J, Ratjen A, Staudinger BJ, Radey MC, Genatossio A, McNamara S, Cook DA, Aitken ML, Gibson RL, Yahr TL, Singh PK.Cystic Fibrosis Lung Function Decline after Within-Host Evolution Increases Virulence of Infecting Pseudomonas Aeruginosa.Am J Respir Crit Care Med. 2021
33093601Varela MC, Roch M, Taglialegna A, Long SW, Saavedra MO, Rose WE, Davis JJ, Hoffman LR, Hernandez RE, Rosato RR, Rosato AE.Carbapenems drive the collateral resistance to ceftaroline in cystic fibrosis patients with MRSA.Commun Biol. 2020
33028687Davis TJ, Karanjia AV, Bhebhe CN, West SB, Richardson M, Bean HD.Pseudomonas aeruginosa Volatilome Characteristics and Adaptations in Chronic Cystic Fibrosis Lung Infections.mSphere. 2020
32994320Vidaillac C, Yong VFL, Aschtgen MS, Qu J, Yang S, Xu G, Seng ZJ, Brown AC, Ali MK, Jaggi TK, Sankaran J, Foo YH, Righetti F, Nedumaran AM, Mac Aogáin M, Roizman D, Richard JA, Rogers TR, Toyofuku M, Luo D, Loh E, Wohland T, Czarny B, Horvat JC, Hansbro PM, Yang L, Li L, Normark S, Henriques Normark B, Chotirmall SH.Sex Steroids Induce Membrane Stress Responses and Virulence Properties in Pseudomonas aeruginosa.mBio. 2020
32983071Zemke AC, Madison CJ, Kasturiarachi N, Pearce LL, Peterson J.Antimicrobial Synergism Toward Pseudomonas aeruginosa by Gallium(III) and Inorganic Nitrite.Front Microbiol. 2020
32936035Davis AS, Chang MY, Brune JE, Hallstrand TS, Johnson B, Lindhartsen S, Hewitt SM, Frevert CW.The Use of Quantitative Digital Pathology to Measure Proteoglycan and Glycosaminoglycan Expression and Accumulation in Healthy and Diseased Tissues.J Histochem Cytochem. 2021
32868171Mayer-Hamblett N, VanDevanter DR.Accelerated Approval or Risk Reduction? How Response Biomarkers Advance Therapeutics through Clinical Trials in Cystic Fibrosis.Trends Mol Med. 2020
32846098Wolter DJ, Ramsey BW.Not Quite the Bully in the Schoolyard: Staphylococcus aureus Can Survive and Coexist with Pseudomonas aeruginosa in the Cystic Fibrosis Lung.Am J Respir Crit Care Med. 2021
32682670VanDevanter DR, Hamblett NM, Simon N, McIntosh J, Konstan MW.Evaluating assumptions of definition-based pulmonary exacerbation endpoints in cystic fibrosis clinical trials.J Cyst Fibros. 2021
32669459Zemke AC, D'Amico EJ, Snell EC, Torres AM, Kasturiarachi N, Bomberger JM.Dispersal of Epithelium-Associated Pseudomonas aeruginosa Biofilms.mSphere. 2020
32644818Sagel SD, Khan U, Heltshe SL, Clancy JP, Borowitz D, Gelfond D, Donaldson SH, Moran A, Ratjen F, VanDalfsen JM, Rowe SM.Clinical Effectiveness of Lumacaftor/Ivacaftor in Patients with Cystic Fibrosis Homozygous for F508del-CFTR. A Clinical Trial.Ann Am Thorac Soc. 2021
32641830Mok BY, de Moraes MH, Zeng J, Bosch DE, Kotrys AV, Raguram A, Hsu F, Radey MC, Peterson SB, Mootha VK, Mougous JD, Liu DR.A bacterial cytidine deaminase toxin enables CRISPR-free mitochondrial base editing.Nature. 2020
32631930Nelson MT, Wolter DJ, Eng A, Weiss EJ, Vo AT, Brittnacher MJ, Hayden HS, Ravishankar S, Bautista G, Ratjen A, Blackledge M, McNamara S, Nay L, Majors C, Miller SI, Borenstein E, Simon RH, LiPuma JJ, Hoffman LR.Maintenance tobramycin primarily affects untargeted bacteria in the CF sputum microbiome.Thorax. 2020
32571874Hausrath AC, Ramirez NA, Ly AT, McEvoy MM.The bacterial copper resistance protein CopG contains a cysteine-bridged tetranuclear copper cluster.J Biol Chem. 2020
32530919Harrison JJ, Almblad H, Irie Y, Wolter DJ, Eggleston HC, Randall TE, Kitzman JO, Stackhouse B, Emerson JC, Mcnamara S, Larsen TJ, Shendure J, Hoffman LR, Wozniak DJ, Parsek MR.Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections.PLoS Genet. 2020
32522463Mayer-Hamblett N, van Koningsbruggen-Rietschel S, Nichols DP, VanDevanter DR, Davies JC, Lee T, Durmowicz AG, Ratjen F, Konstan MW, Pearson K, Bell SC, Clancy JP, Taylor-Cousar JL, De Boeck K, Donaldson SH, Downey DG, Flume PA, Drevinek P, Goss CH, Fajac I, Magaret AS, Quon BS, Singleton SM, VanDalfsen JM, Retsch-Bogart GZ.Building global development strategies for cf therapeutics during a transitional cftr modulator era.J Cyst Fibros. 2020
32515951Picconi P, Hind CK, Nahar KS, Jamshidi S, Di Maggio L, Saeed N, Evans B, Solomons J, Wand ME, Sutton JM, Rahman KM.New Broad-Spectrum Antibiotics Containing a Pyrrolobenzodiazepine Ring with Activity against Multidrug-Resistant Gram-Negative Bacteria.J Med Chem. 2020
32371400Pham VD, To TA, Gagné-Thivierge C, Couture M, Lagüe P, Yao D, Picard MÈ, Lortie LA, Attéré SA, Zhu X, Levesque RC, Charette SJ, Shi R.Structural insights into the putative bacterial acetylcholinesterase ChoE and its substrate inhibition mechanism.J Biol Chem. 2020
32341341Ortega DR, Yang W, Subramanian P, Mann P, Kjær A, Chen S, Watts KJ, Pirbadian S, Collins DA, Kooger R, Kalyuzhnaya MG, Ringgaard S, Briegel A, Jensen GJ.Repurposing a chemosensory macromolecular machine.Nat Commun. 2020
32327704Barrett SLR, Holmes EA, Long DR, Shean RC, Bautista GE, Ravishankar S, Peddu V, Cookson BT, Singh PK, Greninger AL, Salipante SJ.Cell free DNA from respiratory pathogens is detectable in the blood plasma of Cystic Fibrosis patients.Sci Rep. 2020
32291159Magaret AS, Salerno J, Deen JF, Kloster M, Mayer-Hamblett N, Ramsey BW, Nichols DP.Real-world evidence in cystic fibrosis modulator development: Establishing a path forward.J Cyst Fibros. 2020
32265330Cruz RL, Asfahl KL, Van den Bossche S, Coenye T, Crabbé A, Dandekar AA.RhlR-Regulated Acyl-Homoserine Lactone Quorum Sensing in a Cystic Fibrosis Isolate of Pseudomonas aeruginosa.mBio. 2020
32156826Behrens HM, Lowe ED, Gault J, Housden NG, Kaminska R, Weber TM, Thompson CMA, Mislin GLA, Schalk IJ, Walker D, Robinson CV, Kleanthous C.Pyocin S5 Import into Pseudomonas aeruginosa Reveals a Generic Mode of Bacteriocin Transport.mBio. 2020
32109430Godfrey EM, Mody S, Schwartz MR, Heltshe SL, Taylor-Cousar JL, Jain R, Sufian S, Josephy T, Aitken ML.Contraceptive use among women with cystic fibrosis: A pilot study linking reproductive health questions to the Cystic Fibrosis Foundation National Patient Registry.Contraception. 2020
31993716Aitken ML, Szkudlinska MA, Boyko EJ, Ng D, Utzschneider KM, Kahn SE.Impaired counterregulatory responses to hypoglycaemia following oral glucose in adults with cystic fibrosis.Diabetologia. 2020
31961914Meeker SM, Mears KS, Sangwan N, Brittnacher MJ, Weiss EJ, Treuting PM, Tolley N, Pope CE, Hager KR, Vo AT, Paik J, Frevert CW, Hayden HS, Hoffman LR, Miller SI, Hajjar AM.CFTR dysregulation drives active selection of the gut microbiome.PLoS Pathog. 2020
31959989Hayden HS, Eng A, Pope CE, Brittnacher MJ, Vo AT, Weiss EJ, Hager KR, Martin BD, Leung DH, Heltshe SL, Borenstein E, Miller SI, Hoffman LR.Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure.Nat Med. 2020
31958441Ramos KJ, Kapnadak SG, Bradford MC, Somayaji R, Morrell ED, Pilewski JM, Lease ED, Mulligan MS, Aitken ML, Gries CJ, Goss CH.Underweight Patients With Cystic Fibrosis Have Acceptable Survival Following Lung Transplantation: A United Network for Organ Sharing Registry Study.Chest. 2020
31877028Mahasenan KV, Batuecas MT, De Benedetti S, Kim C, Rana N, Lee M, Hesek D, Fisher JF, Sanz-Aparicio J, Hermoso JA, Mobashery S.Catalytic Cycle of Glycoside Hydrolase BglX from Pseudomonas aeruginosa and Its Implications for Biofilm Formation.ACS Chem Biol. 2020
31875166Somayaji R, Goss CH.Duration of antibiotic therapy in non-cystic fibrosis bronchiectasis.Curr Pulmonol Rep. 2019
31870630Sagel SD, Wagner BD, Ziady A, Kelley T, Clancy JP, Narvaez-Rivas M, Pilewski J, Joseloff E, Sha W, Zelnick L, Setchell KDR, Heltshe SL, Muhlebach MS.Utilizing centralized biorepository samples for biomarkers of cystic fibrosis lung disease severity.J Cyst Fibros. 2020
31860331Mall MA, Mayer-Hamblett N, Rowe SM.Cystic Fibrosis: Emergence of Highly Effective Targeted Therapeutics and Potential Clinical Implications.Am J Respir Crit Care Med. 2020
31761739Gifford AH, Mayer-Hamblett N, Pearson K, Nichols DP.Answering the call to address cystic fibrosis treatment burden in the era of highly effective CFTR modulator therapy.J Cyst Fibros. 2019
31727592Wolter DJ, Onchiri FM, Emerson J, Precit MR, Lee M, McNamara S, Nay L, Blackledge M, Uluer A, Orenstein DM, Mann M, Hoover W, Gibson RL, Burns JL, Hoffman LR.Prevalence and clinical associations of Staphylococcus aureus small-colony variant respiratory infection in children with cystic fibrosis (SCVSA): a multicentre, observational study.Lancet Respir Med. 2019
31697873Middleton PG, Mall MA, Dřevínek P, Lands LC, McKone EF, Polineni D, Ramsey BW, Taylor-Cousar JL, Tullis E, Vermeulen F, Marigowda G, McKee CM, Moskowitz SM, Nair N, Savage J, Simard C, Tian S, Waltz D, Xuan F, Rowe SM, Jain R.Elexacaftor-Tezacaftor-Ivacaftor for Cystic Fibrosis with a Single Phe508del Allele.N Engl J Med. 2019
31679946Heijerman HGM, McKone EF, Downey DG, Van Braeckel E, Rowe SM, Tullis E, Mall MA, Welter JJ, Ramsey BW, McKee CM, Marigowda G, Moskowitz SM, Waltz D, Sosnay PR, Simard C, Ahluwalia N, Xuan F, Zhang Y, Taylor-Cousar JL, McCoy KS.Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial.Lancet. 2019
31666699Ross BD, Verster AJ, Radey MC, Schmidtke DT, Pope CE, Hoffman LR, Hajjar AM, Peterson SB, Borenstein E, Mougous JD.Human gut bacteria contain acquired interbacterial defence systems.Nature. 2019
31661302Nichols DP, Odem-Davis K, Cogen JD, Goss CH, Ren CL, Skalland M, Somayaji R, Heltshe SL.Pulmonary Outcomes Associated with Long-Term Azithromycin Therapy in Cystic Fibrosis.Am J Respir Crit Care Med. 2020
31659730Goss CH.Acute Pulmonary Exacerbations in Cystic Fibrosis.Semin Respir Crit Care Med. 2019
31617901Roch M, Varela MC, Taglialegna A, Rosato AE.Tedizolid is a promising antimicrobial option for the treatment of Staphylococcus aureus infections in cystic fibrosis patients.J Antimicrob Chemother. 2020
31511582Li J, Wan SJ, Metruccio MME, Ma S, Nazmi K, Bikker FJ, Evans DJ, Fleiszig SMJ.DMBT1 inhibition of Pseudomonas aeruginosa twitching motility involves its N-glycosylation and cannot be conferred by the Scavenger Receptor Cysteine-Rich bacteria-binding peptide domain.Sci Rep. 2019
31508501Miyazaki T, Gharib SA, Hsu YA, Xu K, Khodakivskyi P, Kobayashi A, Paragas J, Klose AD, Francis KP, Dubikovskaya E, Page-McCaw PS, Barasch J, Paragas N.Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice.Commun Biol. 2019
31508501Miyazaki T, Gharib SA, Hsu YA, Xu K, Khodakivskyi P, Kobayashi A, Paragas J, Klose AD, Francis KP, Dubikovskaya E, Page-McCaw PS, Barasch J, Paragas N.Cell-specific image-guided transcriptomics identifies complex injuries caused by ischemic acute kidney injury in mice.Commun Biol. 2019
31416774Rogers GB, Taylor SL, Hoffman LR, Burr LD.The impact of CFTR modulator therapies on CF airway microbiology.J Cyst Fibros. 2020
31218221Taylor-Cousar JL, Mall MA, Ramsey BW, McKone EF, Tullis E, Marigowda G, McKee CM, Waltz D, Moskowitz SM, Savage J, Xuan F, Rowe SM.Clinical development of triple-combination CFTR modulators for cystic fibrosis patients with one or two F508del alleles.ERJ Open Res. 2019
31147301Cogen JD, Whitlock KB, Gibson RL, Hoffman LR, VanDevanter DR.The use of antimicrobial susceptibility testing in pediatric cystic fibrosis pulmonary exacerbations.J Cyst Fibros. 2019
31126950John-White M, Gardiner J, Johanesen P, Lyras D, Dumsday G.?-Aminopeptidases: Insight into Enzymes without a Known Natural Substrate.Appl Environ Microbiol. 2019
31126901Gold LS, Patrick DL, Hansen RN, Goss CH, Kessler L.Correspondence between lung function and symptom measures from the Cystic Fibrosis Respiratory Symptom Diary-Chronic Respiratory Infection Symptom Score (CFRSD-CRISS).J Cyst Fibros. 2019
31060355Wu X, Siehnel RJ, Garudathri J, Staudinger BJ, Hisert KB, Ozer EA, Hauser AR, Eng JK, Manoil C, Singh PK, Bruce JE.In Vivo Proteome of Pseudomonas aeruginosa in Airways of Cystic Fibrosis Patients.J Proteome Res. 2019
31053538Rosenfeld M, Cunningham S, Harris WT, Lapey A, Regelmann WE, Sawicki GS, Southern KW, Chilvers M, Higgins M, Tian S, Cooke J, Davies JC; KLIMB study group.An open-label extension study of ivacaftor in children with CF and a CFTR gating mutation initiating treatment at age 2-5?years (KLIMB).J Cyst Fibros. 2019
31038945Punchi Hewage AND, Yao H, Nammalwar B, Gnanasekaran KK, Lovell S, Bunce RA, Eshelman K, Phaniraj SM, Lee MM, Peterson BR, Battaile KP, Reitz AB, Rivera M.Small Molecule Inhibitors of the BfrB-Bfd Interaction Decrease Pseudomonas aeruginosa Fitness and Potentiate Fluoroquinolone Activity.J Am Chem Soc. 2019
31018133Jorth P, Ehsan Z, Rezayat A, Caldwell E, Pope C, Brewington JJ, Goss CH, Benscoter D, Clancy JP, Singh PK.Direct Lung Sampling Indicates That Established Pathogens Dominate Early Infections in Children with Cystic Fibrosis.Cell Rep. 2019
31007939Kapnadak SG, Ramos KJ, Lopriore AM, Goss CH, Aitken ML.A Survey Identifying Nutritional Needs in a Contemporary Adult Cystic Fibrosis Cohort.BMC Nutr. 2019
31003953Ramos KJ, Hobler MR, Engelberg RA, Curtis JR, Zander MI, Howard SS, Goss CH, Aitken ML.Addressing lung transplant with adults with cystic fibrosis: A qualitative analysis of patients' perspectives and experiences.J Cyst Fibros. 2019
30923236Jeukens J, Emond-Rheault JG, Freschi L, Kukavica-Ibrulj I, Levesque RC.Major Release of 161 Whole-Genome Sequences from the International Pseudomonas Consortium Database.Microbiol Resour Announc. 2019
30917288Ramsey BW, Downey GP, Goss CH.Update in Cystic Fibrosis 2018.Am J Respir Crit Care Med. 2019
30889361Bhatraju PK, Hisert KB, Aitken ML, Goss CH, Liles WC, Altemeier WA.Higher Plasma Endothelial Markers in Adults with Cystic Fibrosis Compared with Healthy Age-matched Control Subjects.Ann Am Thorac Soc. 2019
30850547Kostylev M, Kim DY, Smalley NE, Salukhe I, Greenberg EP, Dandekar AA.Evolution of the Pseudomonas aeruginosa quorum-sensing hierarchy.Proc Natl Acad Sci U S A. 2019
30846553Chen R, Déziel E, Groleau MC, Schaefer AL, Greenberg EP.Social cheating in a Pseudomonas aeruginosa quorum-sensing variant.Proc Natl Acad Sci U S A. 2019
30840835Somayaji R, Russell R, Cogen JD, Goss CH, Nick SE, Saavedra MT, Taylor-Cousar JL, Nick JA, Nichols DP.Oral Azithromycin Use and the Recovery of Lung Function from Pulmonary Exacerbations Treated with Intravenous Tobramycin or Colistimethate in Adults with Cystic Fibrosis.Ann Am Thorac Soc. 2019
30804897Sheng S, Xin L, Yam JKH, Salido MM, Khong NZJ, Liu Q, Chea RA, Li HY, Yang L, Liang ZX, Xu L.The MapZ-Mediated Methylation of Chemoreceptors Contributes to Pathogenicity of Pseudomonas aeruginosa.Front Microbiol. 2019
30793044Martínez E, Cosnahan RK, Wu M, Gadila SK, Quick EB, Mobley JA, Campos-Gómez J.Oxylipins mediate cell-to-cell communication in Pseudomonas aeruginosa.Commun Biol. 2019
30784601Nelson MT, Pope CE, Marsh RL, Wolter DJ, Weiss EJ, Hager KR, Vo AT, Brittnacher MJ, Radey MC, Hayden HS, Eng A, Miller SI, Borenstein E, Hoffman LR.Human and Extracellular DNA Depletion for Metagenomic Analysis of Complex Clinical Infection Samples Yields Optimized Viable Microbiome Profiles.Cell Rep. 2019
30782655Martín-Mora D, Ortega Á, Matilla MA, Martínez-Rodríguez S, Gavira JA, Krell T.The Molecular Mechanism of Nitrate Chemotaxis via Direct Ligand Binding to the PilJ Domain of McpN.mBio. 2019
30782628Zhou H, Wang M, Smalley NE, Kostylev M, Schaefer AL, Greenberg EP, Dandekar AA, Xu F.Modulation of Pseudomonas aeruginosa Quorum Sensing by Glutathione.J Bacteriol. 2019
30777898Limoli DH, Hoffman LR.Help, hinder, hide and harm: what can we learn from the interactions between Pseudomonas aeruginosa and Staphylococcus aureus during respiratory infections?Thorax. 2019
30759072Norris AW, Ode KL, Merjaneh L, Sanda S, Yi Y, Sun X, Engelhardt JF, Hull RL.Survival in a bad neighborhood: pancreatic islets in cystic fibrosis.J Endocrinol. 2019
30682383Scoville DK, Nolin JD, Ogden HL, An D, Afsharinejad Z, Johnson BW, Bammler TK, Gao X, Frevert CW, Altemeier WA, Hallstrand TS, Kavanagh TJ.Quantum dots and mouse strain influence house dust mite-induced allergic airway disease.Toxicol Appl Pharmacol. 2019
30672141Goetz D, Kopp BT, Salvator A, Moore-Clingenpeel M, McCoy K, Leung DH, Kloster M, Ramsey BR, Heltshe SH, Borowitz D.Pulmonary findings in infants with cystic fibrosis during the first year of life: Results from the Baby Observational and Nutrition Study (BONUS) cohort study.Pediatr Pulmonol. 2019
30662103Keppler EAH, Jenkins CL, Davis TJ, Bean HD.Advances in the application of comprehensive two-dimensional gas chromatography in metabolomics.Trends Analyt Chem. 2018
30658043Nichols DP, Durmowicz AG, Field A, Flume PA, VanDevanter DR, Mayer-Hamblett N.Developing Inhaled Antibiotics in Cystic Fibrosis: Current Challenges and Opportunities.Ann Am Thorac Soc. 2019
30580531Gifford AH, Heltshe SL, Goss CH.CFTR Modulator Use Is Associated with Higher Hemoglobin Levels in Individuals with Cystic Fibrosis.Ann Am Thorac Soc. 2019
30528757Simon TD, Schaffzin JK, Stevenson CB, Willebrand K, Parsek M, Hoffman LR.Cerebrospinal Fluid Shunt Infection: Emerging Paradigms in Pathogenesis that Affect Prevention and Treatment.J Pediatr. 2019
30496396Freschi L, Vincent AT, Jeukens J, Emond-Rheault JG, Kukavica-Ibrulj I, Dupont MJ, Charette SJ, Boyle B, Levesque RC.The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity.Genome Biol Evol. 2019
30477895Kopp BT, Joseloff E, Goetz D, Ingram B, Heltshe SL, Leung DH, Ramsey BW, McCoy K, Borowitz D.Urinary metabolomics reveals unique metabolic signatures in infants with cystic fibrosis.J Cyst Fibros. 2019
30449724Ragheb MN, Thomason MK, Hsu C, Nugent P, Gage J, Samadpour AN, Kariisa A, Merrikh CN, Miller SI, Sherman DR, Merrikh H.Inhibiting the Evolution of Antibiotic Resistance.Mol Cell. 2019
30445062Gharib SA, McMahan RS, Eddy WE, Long ME, Parks WC, Aitken ML, Manicone AM.Transcriptional and functional diversity of human macrophage repolarization.J Allergy Clin Immunol. 2019
30364027Kim GJ, Merjaneh L.Pediatric Case Series of Cystic Fibrosis, Diabetes, and Islet Cell Autoimmunity.Clin Diabetes. 2018
30334693Davies JC, Moskowitz SM, Brown C, Horsley A, Mall MA, McKone EF, Plant BJ, Prais D, Ramsey BW, Taylor-Cousar JL, Tullis E, Uluer A, McKee CM, Robertson S, Shilling RA, Simard C, Van Goor F, Waltz D, Xuan F, Young T, Rowe SM; VX16-659-101 Study Group.VX-659-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles.N Engl J Med. 2018
30334692Keating D, Marigowda G, Burr L, Daines C, Mall MA, McKone EF, Ramsey BW, Rowe SM, Sass LA, Tullis E, McKee CM, Moskowitz SM, Robertson S, Savage J, Simard C, Van Goor F, Waltz D, Xuan F, Young T, Taylor-Cousar JL; VX16-445-001 Study Group.VX-445-Tezacaftor-Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles.N Engl J Med. 2018
30323260Klose AD, Paragas N.Automated quantification of bioluminescence images.Nat Commun. 2018
30257953Goss CH, Kaneko Y, Khuu L, Anderson GD, Ravishankar S, Aitken ML, Lechtzin N, Zhou G, Czyz DM, McLean K, Olakanmi O, Shuman HA, Teresi M, Wilhelm E, Caldwell E, Salipante SJ, Hornick DB, Siehnel RJ, Becker L, Britigan BE, Singh PK.Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections.Sci Transl Med. 2018
30254118Reichhardt C, Wong C, Passos da Silva D, Wozniak DJ, Parsek MR.CdrA Interactions within the Pseudomonas aeruginosa Biofilm Matrix Safeguard It from Proteolysis and Promote Cellular Packing.mBio. 2018
30181125Irons J, Hodge-Hanson KM, Downs DM.PA5339, a RidA Homolog, Is Required for Full Growth in Pseudomonas aeruginosa.J Bacteriol. 2018
30170756Gold LS, Patrick DL, Hansen RN, Beckett V, Goss CH, Kessler L.Correspondence between symptoms and preference-based health status measures in the STOP study.J Cyst Fibros. 2019
30154259Ding F, Oinuma KI, Smalley NE, Schaefer AL, Hamwy O, Greenberg EP, Dandekar AA.The Pseudomonas aeruginosa Orphan Quorum Sensing Signal Receptor QscR Regulates Global Quorum Sensing Gene Expression by Activating a Single Linked Operon.mBio. 2018
30146268McColley SA, Konstan MW, Ramsey BW, Stuart Elborn J, Boyle MP, Wainwright CE, Waltz D, Vera-Llonch M, Marigowda G, Jiang JG, Rubin JL.Lumacaftor/Ivacaftor reduces pulmonary exacerbations in patients irrespective of initial changes in FEV1.J Cyst Fibros. 2019
30089726Abou Alaiwa MH, Launspach JL, Grogan B, Carter S, Zabner J, Stoltz DA, Singh PK, McKone EF, Welsh MJ.Ivacaftor-induced sweat chloride reductions correlate with increases in airway surface liquid pH in cystic fibrosis.JCI Insight. 2018
30068264Long ME, Gong KQ, Volk JS, Eddy WE, Chang MY, Frevert CW, Altemeier WA, Gale M Jr, Liles WC, Manicone AM.Matrix metalloproteinase 28 is regulated by TRIF- and type I IFN-dependent signaling in macrophages.Innate Immun. 2018
30046852Templin AT, Meier DT, Willard JR, Wolden-Hanson T, Conway K, Lin YG, Gillespie PJ, Bokvist KB, Attardo G, Kahn SE, Scheuner D, Hull RL.Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice.Diabetologia. 2018
30005828Chi DL, Rosenfeld M, Mancl L, Chung WO, Presland RB, Sarvas E, Rothen M, Alkhateeb A, McNamara S, Genatossio A, Virella-Lowell I, Milla C, Scott J.Age-related heterogeneity in dental caries and associated risk factors in individuals with cystic fibrosis ages 6-20 years: A pilot study.J Cyst Fibros. 2018
30003009Marsh RL, Nelson MT, Pope CE, Leach AJ, Hoffman LR, Chang AB, Smith-Vaughan HC.How low can we go? The implications of low bacterial load in respiratory microbiota studies.Pneumonia (Nathan). 2018
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26665020Ruddy J, Emerson J, McNamara S, Genatossio A, Breuner C, Weber T, Rosenfeld M.Yoga as a Therapy for Adolescents and Young Adults With Cystic Fibrosis: A Pilot Study.Glob Adv Health Med. 2015
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25551340Quon BS, Goss CH.Adult-onset asthma prevention. Should we be investing in antioxidant defense?Am J Respir Crit Care Med. 2015
25459563Cuthbertson L, Rogers GB, Walker AW, Oliver A, Hoffman LR, Carroll MP, Parkhill J, Bruce KD, van der Gast CJ.Implications of multiple freeze-thawing on respiratory samples for culture-independent analyses.J Cyst Fibros. 2015
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25229185Zemke AC, Shiva S, Burns JL, Moskowitz SM, Pilewski JM, Gladwin MT, Bomberger JM.Nitrite modulates bacterial antibiotic susceptibility and biofilm formation in association with airway epithelial cells.Free Radic Biol Med. 2014
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