Past Pilots

Funding Source	Principal Investigator Department	Funding Period	Project title
NIH P30 CFRTC	Jim Kublin, MD, MPH Principal Staff Scientist Vaccine and Infectious Disease Division, Fred Hutch	2020-23	Investigating Mechanisms of Vaccine Response Deficiency in Cystic Fibrosis
NIH P30 CFRTC	Sakeneh Zraika, PhD Research Associate Professor, Medicine, Metabolism	2020-23	Impact of Intra-Islet GLP-1 Signaling on ß-cell Function in CFRD
CFF RDP	Eric Morrell, MD, MA Acting Instructor, Pulmonary	2019-22	Immune Tolerance and Inflammation in Lung Transplant Rejection
CFF RDP	David Sherman, PhD Professor and Chair, Microbiology	2019-21	Inferring drug interactions in M. abscessus using chemo-genomics and orthology
CFF RDP	Richard James, PhD Assistant Professor, Pediatrics Jason Debley, MD, MPH Associate Professor, Pediatrics	2019-20	Approach to CFTR Editing in Differentiated Airway Epithelial Cells
NIH P30 CFRTC	Marion Pepper, PhD Associate Professor, Immunology	2018-21	Pseudomonas-specific immune responses in CF patients
NIH P30 CFRTC	Jisun Paik, PhD Research Assistant Professor, Comparative Medicine Luke Hoffman, MD, PhD Associate Professor, Pediatrics	2018-20	Gastrointestinal dysbiosis as a modifier of CF infant somatic growth: A murine investigation
NIH P30 CFRTC	Stephen Salipante, MD, PhD Associate Professor, Immunology	2018-20	Cell-free Bacterial DNA to Identify Mycobacterial Lung Pathogens in CF
CFF RDP	Andrew Graustein, MD Acting Instructor, Pulmonary and Critical Care	2017-20	The NLRP3 Inflammasome in The Cystic Fibrosis Lung
CFF RDP	Thomas Hawn, MD, PhD Professor, Allergy and Infectious Diseases	2017-19	The Inflammasome in Cystic Fibrosis
CFF RDP	Jason Debley, MD, MPH Associate Professor, Pediatrics David Nichols, MD Associate Professor, Pediatrics	2017-19	Testing association between epithelial chloride transport and measures of clinical improvement
NIH P30 CFRTC	Matthew Parsek, PhD Professor, Microbiology	2016-20	Microbial colonization and adaptation to the CF gut
NIH P30 CFRTC	Neal Paragas, PhD Research Assistant Professor, Medicine (Nephrology)	2016-19	Identification of Biomarkers for Cystic Fibrosis Associated Nephrotoxicity
NIH P30 CFRTC	Lynn Hajjar, DVM, PhD Research Associate Professor, Comparative Medicine Piper Treuting, DVM, MS Associate Professor, Comparative Medicine	2016-18	Lung and gastrointestinal homeostasis in a germ-free CF mouse model
NIH P30 CFRTC	Marika Bogdani, PhD Staff Scientist, Matrix Biology Program Benaroya Research Institute	2016-17	Hyalouronan and hlyaladherins in the pathogenesis of cystic fibrosis related diabetes
CFF RDP	Steve Salipante, MD, PhD Assistant Professor, Laboratory Medicine	2015-18	Mechanisms and fitness of spontaneous aztreonam resistance in Pseudomonas aeruginosa
CFF RDP	William Altemeier, MD Associate Professor, Pulmonary	2015-18	Role of the Microvasculature in Neutrophilic Lung Disease of Cystic Fibrosis
NIH P30 CFRTC	Steven Kahn, MB, ChB Professor, Metabolism	2014-19	Mechanisms of Late Hypoglycemia in Cystic Fibrosis
NIH P30 CFRTC	Ian de Boer, MD Associate Professor, Nephrology	2014-18	Vitamin D metabolism in cystic fibrosis
CFF RDP	Rafael Hernandez, MD, PhD Assistant Professor, Pediatrics	2014-17	Efflux Pumps in Nontuberculosis Mycobacteria
NIH P30 CFRTC	Anne Manicone, MD Associate Professor, Pulmonary and Critical Care	2014-17	Functional Consequences and Signaling Pathways of Macrophage Repolarization
CFF RDP	Donald Chi, DDS, PhD Associate Professor, Dentistry	2013-17	Testing a Multifactorial Caries Model for Pediatric Patients with Cystic Fibrosis
NIH P30 CFRTC	Elhanan Borenstein, PhD Associate Professor Genome Sciences	2013-14	Advanced computational methods for identifying compositional shifts in the CF gut microbiome
NIH P30 CFRTC	Lucas Hoffman, MD, PhD Associate Professor Pediatrics	2013-14	Acute Effects of Kalydeco in People with CF and the G551D Mutation
NIH P30 CFRTC	Rebecca Hull, PhD Research Associate Professor, Metabolism Srinath Sanda, MD Assistant Professor, Pediatrics, UCSF	2012-17	Role of Islet Amyloid and IL-1β Signaling in β-cell Loss in Cystic Fibrosis-Related Diabetes
NIH P30 CFRTC	Ian Sweet, PhD Research Associate Professor, Metabolism	2012-15	Biochemical Mechanisms Mediating Impaired Insulin Secretion in Mouse Models of Cystic Fibrosis
NIH P30 CFRTC	Lev Becker, PhD Assistant Professor, Pediatrics, Univer of Chicago	2012-15	Investigating the effects of CFTR Correction on Myeloid Cell Function
NIH P30 CFRTC	Lev Becker, PhD Assistant Professor, Pulmonary and Critical Care	2010-13	Macrophage and Dendritic Cell Pathways in Cystic Fibrosis
NIH P30 CFRTC	Lucas Hoffman, MD, PhD Associate Professor Pediatrics	2010-13	Describing the gut microbiome of early childhood and infant Cystic Fibrosis patients