CF Research Translation Center and Research Development Program
Seattle Children’s Research Institute
University of Washington
2001 8th Ave
Seattle, WA 98121


The CFRTC and CF RDP membership has a research base which totals over $20 million in direct costs annually for active ongoing individual research grants as well as $5 million in programmatic infrastructure grants. We have identified ten areas of research emphasis as outlined below. Emphasis areas are defined as a common research interest consisting of at least 3 collaborating and independently funded investigators who are benefitting from one or more biomedical core services and/or receiving pilot funding.

  • Translational research
  • Clinical outcome measures, biomarkers and study design
  • Effect of P. aeruginosa acquisition on host-pathogen interactions and adaptations
  • Growth and nutrition in infants with CF
  • International academic study coordination
  • Microbial interactions
  • Antibiotic resistance and virulence factors
  • Bacterial communities in GI and respiratory tracts
  • Macrophage function and host response to lung infection
  • Metabolic consequences of CFTR dysfunction