CF Research Translation Center and Research Development Program
Seattle Children’s Research Institute
University of Washington
2001 8th Ave
Seattle, WA 98121

Past Pilots

ProgramPrincipal Investigator
PeriodProject title
RDPRichard James, PhD
Assistant Professor, Pediatrics
Jason Debley, MD, MPH
Associate Professor, Pediatrics
2019-20Approach to CFTR Editing in Differentiated Airway Epithelial Cells
CFRTCJisun Paik, PhD
Research Assistant Professor, Comparative Medicine
Luke Hoffman, MD, PhD
Associate Professor, Pediatrics
2018-20Gastrointestinal dysbiosis as a modifier of CF infant somatic growth: A murine investigation
CFRTC Stephen Salipante, MD, PhD
Associate Professor, Immunology
2018-20Cell-free Bacterial DNA to Identify Mycobacterial Lung Pathogens in CF
RDPAndrew Graustein, MD
Acting Instructor, Pulmonary and Critical Care
2017-20The NLRP3 Inflammasome in The Cystic Fibrosis Lung
RDPThomas Hawn, MD, PhD
Professor, Allergy and Infectious Diseases
2017-19The Inflammasome in Cystic Fibrosis
RDPJason Debley, MD, MPH
Associate Professor, Pediatrics
David Nichols, MD
Associate Professor, Pediatrics
2017-19Testing association between epithelial chloride transport and measures of clinical improvement
CFRTCMatthew Parsek, PhD
Professor, Microbiology
2016-20Microbial colonization and adaptation to the CF gut
CFRTCNeal Paragas, PhD
Research Assistant Professor, Medicine (Nephrology)
2016-19Identification of Biomarkers for Cystic Fibrosis Associated Nephrotoxicity
CFRTCLynn Hajjar, DVM, PhD
Research Associate Professor, Comparative Medicine
Piper Treuting, DVM, MS
Associate Professor, Comparative Medicine
2016-18Lung and gastrointestinal homeostasis in a germ-free CF mouse model
CFRTCMarika Bogdani, PhD
Staff Scientist, Matrix Biology Program
Benaroya Research Institute
2016-17Hyalouronan and hlyaladherins in the pathogenesis of cystic fibrosis related diabetes
RDPSteve Salipante, MD, PhD
Assistant Professor, Laboratory Medicine
2015-18Mechanisms and fitness of spontaneous aztreonam resistance in Pseudomonas aeruginosa
RDPWilliam Altemeier, MD
Associate Professor, Pulmonary
2015-18Role of the Microvasculature in Neutrophilic Lung Disease of Cystic Fibrosis
CFRTCSteven Kahn, MB, ChB
Professor, Metabolism
2014-19Mechanisms of Late Hypoglycemia in Cystic Fibrosis
CFRTCIan de Boer, MD
Associate Professor, Nephrology
2014-18Vitamin D metabolism in cystic fibrosis
CFRTCAnne Manicone, MD
Associate Professor, Pulmonary and Critical Care
2014-17Functional Consequences and Signaling Pathways of Macrophage Repolarization
RDPRafael Hernandez, MD, PhD
Assistant Professor, Pediatrics
2014-17Efflux Pumps in Nontuberculosis Mycobacteria
RDPDonald Chi, DDS, PhD
Associate Professor, Dentistry
2013-17Testing a Multifactorial Caries Model for Pediatric Patients with Cystic Fibrosis
CFRTCElhanan Borenstein, PhD
Associate Professor
Genome Sciences
2013-14Advanced computational methods for identifying compositional shifts in the CF gut microbiome
CFRTCLucas Hoffman, MD, PhD
Associate Professor
2013-14Acute Effects of Kalydeco in People with CF and the G551D Mutation
CFRTCRebecca Hull, PhD
Research Associate Professor,
Srinath Sanda, MD
Assistant Professor,
Pediatrics, UCSF
2012-17Role of Islet Amyloid and IL-1β Signaling in β-cell Loss in Cystic Fibrosis-Related Diabetes
CFRTCIan Sweet, PhD
Research Associate Professor,
2012-15Biochemical Mechanisms Mediating Impaired Insulin Secretion in Mouse Models of Cystic Fibrosis
CFRTCLev Becker, PhD
Assistant Professor, Pediatrics, Univer of Chicago
2012-15Investigating the effects of CFTR Correction on Myeloid Cell Function
CFRTCLev Becker, PhD
Assistant Professor, Pulmonary and Critical Care
2010-13Macrophage and Dendritic Cell Pathways in Cystic Fibrosis
CFRTCLucas Hoffman, MD, PhD
Associate Professor
2010-13Describing the gut microbiome of early childhood and infant Cystic Fibrosis patients