CF Research Translation Center and Research Development Program
Seattle Children’s Research Institute
University of Washington
2001 8th Ave
Seattle, WA 98121
206-884-7541

Past Pilots

ProgramPrincipal Investigator
Department
PeriodProject title
RDPRichard James, PhD
Assistant Professor, Pediatrics
Jason Debley, MD, MPH
Associate Professor, Pediatrics
2019-20Approach to CFTR Editing in Differentiated Airway Epithelial Cells
CFRTCJisun Paik, PhD
Research Assistant Professor, Comparative Medicine
Luke Hoffman, MD, PhD
Associate Professor, Pediatrics
2018-20Gastrointestinal dysbiosis as a modifier of CF infant somatic growth: A murine investigation
CFRTC Stephen Salipante, MD, PhD
Associate Professor, Immunology
2018-20Cell-free Bacterial DNA to Identify Mycobacterial Lung Pathogens in CF
RDPAndrew Graustein, MD
Acting Instructor, Pulmonary and Critical Care
2017-20The NLRP3 Inflammasome in The Cystic Fibrosis Lung
RDPThomas Hawn, MD, PhD
Professor, Allergy and Infectious Diseases
2017-19The Inflammasome in Cystic Fibrosis
RDPJason Debley, MD, MPH
Associate Professor, Pediatrics
David Nichols, MD
Associate Professor, Pediatrics
2017-19Testing association between epithelial chloride transport and measures of clinical improvement
CFRTCMatthew Parsek, PhD
Professor, Microbiology
2016-20Microbial colonization and adaptation to the CF gut
CFRTCNeal Paragas, PhD
Research Assistant Professor, Medicine (Nephrology)
2016-19Identification of Biomarkers for Cystic Fibrosis Associated Nephrotoxicity
CFRTCLynn Hajjar, DVM, PhD
Research Associate Professor, Comparative Medicine
Piper Treuting, DVM, MS
Associate Professor, Comparative Medicine
2016-18Lung and gastrointestinal homeostasis in a germ-free CF mouse model
CFRTCMarika Bogdani, PhD
Staff Scientist, Matrix Biology Program
Benaroya Research Institute
2016-17Hyalouronan and hlyaladherins in the pathogenesis of cystic fibrosis related diabetes
RDPSteve Salipante, MD, PhD
Assistant Professor, Laboratory Medicine
2015-18Mechanisms and fitness of spontaneous aztreonam resistance in Pseudomonas aeruginosa
RDPWilliam Altemeier, MD
Associate Professor, Pulmonary
2015-18Role of the Microvasculature in Neutrophilic Lung Disease of Cystic Fibrosis
CFRTCSteven Kahn, MB, ChB
Professor, Metabolism
2014-19Mechanisms of Late Hypoglycemia in Cystic Fibrosis
CFRTCIan de Boer, MD
Associate Professor, Nephrology
2014-18Vitamin D metabolism in cystic fibrosis
CFRTCAnne Manicone, MD
Associate Professor, Pulmonary and Critical Care
2014-17Functional Consequences and Signaling Pathways of Macrophage Repolarization
RDPRafael Hernandez, MD, PhD
Assistant Professor, Pediatrics
2014-17Efflux Pumps in Nontuberculosis Mycobacteria
RDPDonald Chi, DDS, PhD
Associate Professor, Dentistry
2013-17Testing a Multifactorial Caries Model for Pediatric Patients with Cystic Fibrosis
CFRTCElhanan Borenstein, PhD
Associate Professor
Genome Sciences
2013-14Advanced computational methods for identifying compositional shifts in the CF gut microbiome
CFRTCLucas Hoffman, MD, PhD
Associate Professor
Pediatrics
2013-14Acute Effects of Kalydeco in People with CF and the G551D Mutation
CFRTCRebecca Hull, PhD
Research Associate Professor,
Metabolism
Srinath Sanda, MD
Assistant Professor,
Pediatrics, UCSF
2012-17Role of Islet Amyloid and IL-1β Signaling in β-cell Loss in Cystic Fibrosis-Related Diabetes
CFRTCIan Sweet, PhD
Research Associate Professor,
Metabolism
2012-15Biochemical Mechanisms Mediating Impaired Insulin Secretion in Mouse Models of Cystic Fibrosis
CFRTCLev Becker, PhD
Assistant Professor, Pediatrics, Univer of Chicago
2012-15Investigating the effects of CFTR Correction on Myeloid Cell Function
CFRTCLev Becker, PhD
Assistant Professor, Pulmonary and Critical Care
2010-13Macrophage and Dendritic Cell Pathways in Cystic Fibrosis
CFRTCLucas Hoffman, MD, PhD
Associate Professor
Pediatrics
2010-13Describing the gut microbiome of early childhood and infant Cystic Fibrosis patients