CF Research Translation Center and Research Development Program
Seattle Children’s Research Institute
University of Washington
2001 8th Ave
Seattle, WA 98121

Past Pilots

Funding SourcePrincipal Investigator
Funding PeriodProject title
NIH P30 CFRTCJim Kublin, MD, MPH
Principal Staff Scientist
Vaccine and Infectious Disease Division, Fred Hutch
2020-23Investigating Mechanisms of Vaccine Response Deficiency in Cystic Fibrosis
NIH P30 CFRTCSakeneh Zraika, PhD
Research Associate Professor, Medicine, Metabolism
2020-23Impact of Intra-Islet GLP-1 Signaling on ß-cell Function in CFRD
CFF RDPEric Morrell, MD, MA
Acting Instructor, Pulmonary
2019-22Immune Tolerance and Inflammation in Lung Transplant Rejection
CFF RDPDavid Sherman, PhD
Professor and Chair, Microbiology
2019-21Inferring drug interactions in M. abscessus using chemo-genomics and orthology
CFF RDPRichard James, PhD
Assistant Professor, Pediatrics
Jason Debley, MD, MPH
Associate Professor, Pediatrics
2019-20Approach to CFTR Editing in Differentiated Airway Epithelial Cells
NIH P30 CFRTC Marion Pepper, PhD
Associate Professor, Immunology
2018-21Pseudomonas-specific immune responses in CF patients
NIH P30 CFRTCJisun Paik, PhD
Research Assistant Professor, Comparative Medicine
Luke Hoffman, MD, PhD
Associate Professor, Pediatrics
2018-20Gastrointestinal dysbiosis as a modifier of CF infant somatic growth: A murine investigation
NIH P30 CFRTC Stephen Salipante, MD, PhD
Associate Professor, Immunology
2018-20Cell-free Bacterial DNA to Identify Mycobacterial Lung Pathogens in CF
CFF RDPAndrew Graustein, MD
Acting Instructor, Pulmonary and Critical Care
2017-20The NLRP3 Inflammasome in The Cystic Fibrosis Lung
CFF RDPThomas Hawn, MD, PhD
Professor, Allergy and Infectious Diseases
2017-19The Inflammasome in Cystic Fibrosis
CFF RDPJason Debley, MD, MPH
Associate Professor, Pediatrics
David Nichols, MD
Associate Professor, Pediatrics
2017-19Testing association between epithelial chloride transport and measures of clinical improvement
NIH P30 CFRTCMatthew Parsek, PhD
Professor, Microbiology
2016-20Microbial colonization and adaptation to the CF gut
NIH P30 CFRTCNeal Paragas, PhD
Research Assistant Professor, Medicine (Nephrology)
2016-19Identification of Biomarkers for Cystic Fibrosis Associated Nephrotoxicity
NIH P30 CFRTCLynn Hajjar, DVM, PhD
Research Associate Professor, Comparative Medicine
Piper Treuting, DVM, MS
Associate Professor, Comparative Medicine
2016-18Lung and gastrointestinal homeostasis in a germ-free CF mouse model
NIH P30 CFRTCMarika Bogdani, PhD
Staff Scientist, Matrix Biology Program
Benaroya Research Institute
2016-17Hyalouronan and hlyaladherins in the pathogenesis of cystic fibrosis related diabetes
CFF RDPSteve Salipante, MD, PhD
Assistant Professor, Laboratory Medicine
2015-18Mechanisms and fitness of spontaneous aztreonam resistance in Pseudomonas aeruginosa
CFF RDPWilliam Altemeier, MD
Associate Professor, Pulmonary
2015-18Role of the Microvasculature in Neutrophilic Lung Disease of Cystic Fibrosis
NIH P30 CFRTCSteven Kahn, MB, ChB
Professor, Metabolism
2014-19Mechanisms of Late Hypoglycemia in Cystic Fibrosis
NIH P30 CFRTCIan de Boer, MD
Associate Professor, Nephrology
2014-18Vitamin D metabolism in cystic fibrosis
CFF RDPRafael Hernandez, MD, PhD
Assistant Professor, Pediatrics
2014-17Efflux Pumps in Nontuberculosis Mycobacteria
NIH P30 CFRTCAnne Manicone, MD
Associate Professor, Pulmonary and Critical Care
2014-17Functional Consequences and Signaling Pathways of Macrophage Repolarization
CFF RDPDonald Chi, DDS, PhD
Associate Professor, Dentistry
2013-17Testing a Multifactorial Caries Model for Pediatric Patients with Cystic Fibrosis
NIH P30 CFRTCElhanan Borenstein, PhD
Associate Professor
Genome Sciences
2013-14Advanced computational methods for identifying compositional shifts in the CF gut microbiome
NIH P30 CFRTCLucas Hoffman, MD, PhD
Associate Professor
2013-14Acute Effects of Kalydeco in People with CF and the G551D Mutation
NIH P30 CFRTCRebecca Hull, PhD
Research Associate Professor,
Srinath Sanda, MD
Assistant Professor,
Pediatrics, UCSF
2012-17Role of Islet Amyloid and IL-1β Signaling in β-cell Loss in Cystic Fibrosis-Related Diabetes
NIH P30 CFRTCIan Sweet, PhD
Research Associate Professor,
2012-15Biochemical Mechanisms Mediating Impaired Insulin Secretion in Mouse Models of Cystic Fibrosis
NIH P30 CFRTCLev Becker, PhD
Assistant Professor, Pediatrics, Univer of Chicago
2012-15Investigating the effects of CFTR Correction on Myeloid Cell Function
NIH P30 CFRTCLev Becker, PhD
Assistant Professor, Pulmonary and Critical Care
2010-13Macrophage and Dendritic Cell Pathways in Cystic Fibrosis
NIH P30 CFRTCLucas Hoffman, MD, PhD
Associate Professor
2010-13Describing the gut microbiome of early childhood and infant Cystic Fibrosis patients