ADRC Seminar Series - Schedule & Archive

Sue Gardon, Stars, Art of Alzheimer's

The ADRC seminar series occurs on second Mondays, noon - 1 pm.  This replaces the Towards Precision Medicine series hosted during the past funding cycle. The format for 2022 will be remote (via Zoom), with a Zoom option to continue indefinitely.

The topic of the seminar series will be a wide range of areas of relevance to Alzheimer’s disease and related dementias (ADRD), biological heterogeneity, and other themes of the ADRC. The presenters will be a mix of UW, regional, and external (national and international) guests and will also have an eye towards enhancing collaborations. For more information on the ADRC seminar series, please contact Genevieve Wanucha (gwanucha@uw.edu) or Annika Noreen (annikn@uw.edu) or visit the ADRC Talks & Events calendar.

 

Upcoming

 

Mon. May 9, 2022, 12 pm - 1 pm

Title: Health disparities and Alzheimer’s disease in American Indians

Speaker: Astrid Suchy-Dicey, PhD, Assistant Research Professor, Washington State University

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Meeting ID: 943 7427 4795 Passcode: 444398

Bio:

My research focuses on neuroepidemiology within the context of health disparities, with special interest in neuropsychology, neuroimaging, and quantitative analytics. I have graduate certification in public health genetics, machine learning, and a background in molecular pathology. I am PI of two large studies focused on cognitive and socio-cultural features related to Alzheimer’s disease and vascular aging in American Indians (R01AG070822, RF1AG071677) and a plasma biomarkers pilot study in the same population, funded by University of Washington Alzheimer’s Disease Research Center (UW ADRC). I also lead a large, longitudinal epidemiology study with detailed cognitive, clinical, and imaging data on more than 1,000 American Indian adults over two timepoints (K01AG057821 Suchy-Dicey; R01HL093086 Buchwald; P50AG005136 Grabowski), including detailed dementia case review and adjudications efforts in collaboration with UW ADRC Clinical Core. I have more than 15 years’ experience working with large population-based cohorts, among them the Cardiovascular Health Study and the Seattle Kidney Study. I serve as chair of the Strong Heart Study Neurology working group, and am involved in the Collaborative Cohort of Cohorts for COVID-19 Research (C4R) study. I mentor several graduate students, post-doctorates, and junior faculty, including primary mentoring on the Resource Center for Minority Aging Research in Alzheimer’s Disease center at WSU and the Alzheimer’s Disease Center of Excellence at UC Denver. I serve on the WSU Institutional Review Board and the WSU Faculty Senate Graduate Studies Committee, and chair the IREACH Publications & Presentations committee.

 

 

Past Seminars

Mon. April 11, 2022, 12 pm - 1 pm Title:  Title: Practice effects in Mild Cognitive Impairment and Alzheimer's disease: Why two in the bush might be better than one in the hand. Speaker: Kevin Duff, PhD, Professor of Neurology, University of Utah

Mon. Mar. 14, 12 pm - 1 pm   Speaker: Don Elbert, PhD, Associate Professor of Neurology, University of Texas at Austin Title: Age and Alzheimer’s Disease-related changes in the kinetics of CSF-based, blood-brain barrier and proteolytic Aβ clearance in humans Flyer

Mon. Jan. 10, 2022 Special two-part ADRC Seminar Series with special guest Karl Herrup, PhD, Professor of Neurobiology, University of Pittsburgh School of Medicine/Investigator, University of Pittsburgh ADRC. Title: Location, location, location: DNA in microglial cytoplasm spells trouble for the brain /  Book discussion” “How Not to Study a Disease: the Story of Alzheimer’s by Dr. Karl Kerrup, PhD. Moderated by Jeff Iliff, PhD, Professor, UW Dept. Psychiatry & Behavioral Sciences/UW Neurology/UW ADRC REC Lead

Monday, November 8, 2021 Speakers: Rebecca Hodge, PhD, Assistant Investigator, Allen Institute / Jeremy Miller, PhD, Senior Scientist, Allen Institute. Title: Alzheimer's Disease Brain Cell Atlas Center: Progress on a platform for cell type-level transcriptomic and epigenomic interrogation of Alzheimer’s Disease

Mon. October. 11, 2021 Speaker: Jet M.J. Vonk  MA, MS, MD, PhD, Associate Research Scientist, Columbia University Irving Medical Center, Department of Neurology, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain. Title: Leveraging linguistics and longitudinal change to identify early cognitive markers of dementia

Mon. Sept 13 Tracy Young-Pearse, PhD, Associate Professor, Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital and Harvard Medical School. Title: Stem cell derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors

Mon. May. 10 Geir Ringstad, MD, PhD, Senior Consultant Neuroradiologist and Chair of the Neuroimaging Research Group at Oslo University Hospital in Norway. Title: Human Brain Extra-Vascular Pathways and Molecular Clearance Function Assessed with CSF Tracer (Glymphatic MRI)

April 12: Jesse Mez, MD, MS, Associate Professor of Neurology at Boston University School of Medicine. Title: Chronic Traumatic Encephalopathy: Exploring Neuropathology, Clinical Presentation and Risk Factors 

March 8 Min Shi, PhD, Research Assistant Professor, UW Medicine Laboratory Medicine & Pathology. Title: Extracellular vesicles as a biomarker source for neurodegenerative disorders 

January 11, 12pm - 1pm Donna Wilcock, PhD, Assistant Dean of Biomedicine, Associate Director, Sanders-Brown Center on Aging/Robert P. and Mildred A. Moores Endowed Chair in Alzheimer’s Disease/ Professor, Department of Physiology, University Kentucky College of Medicine. Title: Integration of mouse and human studies for biomarker discovery in VCID Flyer 

December 14, 12 pm - 1 pm: James Rini, MD, MPH, Behavioral Neurology Fellow at the University of California, San Francisco (UCSF) Memory and Aging Center. Title: VR. Neurology or: How I Learned To Stop Worrying And Love Teleneurology. Flyer 

October 5, 4:00-5:00 pm: Michael J. MacCoss, Ph.D, Professor of Genome Sciences, UW. Title: Next Generation Translational Proteomics of Alzheimer's Disease 

March 2, 2020: Spero Manson, PhD. Distinguished Professor, Public Health and Psychiatry Director, Centers for American Indian and Alaska Native Health University of Colorado Denver’s Anschutz Medical Center Colorado School of Public Health Title: Native Peoples and the All of Us Research Program: Inclusion, Collaboration, Governance, and Benefit (VIDEO) (Summary PDF)

Febrary 2020 Pilot Project Update: Robert J. Freishtat, M.D., M.P.H., Senior Investigator in the Center for Genetic Medicine of the Children’s Research Institute, Professor in Pediatrics and Genomics and Precision Medicine at The George Washington University School of Medicine and Health Sciences. Obesity and Dementia: MicroRNAs from Adipocyte-derived Small Extracellular Vesicles are associated with Neurodegenerative Pathways. (Summary PDF)

February 3, 2020 Dr. Julie Saugstad, PhD, Professor, Oregon Health & Sciences University. Title: MicroRNA Biomarkers for AD: Performance in Mild Cognitive Impairment and Traumatic Brain Injury (Summary PDF)

December 2, 2019 Dr. Ed Lein, PhD, Investigator, Allen Institute for Brain Science, Affiliate Professor, UW Dept. of Neurological Surgery. Title: From A Human Brain Cell Census Towards Precision Medicine

November 4, 2019 Dr. Ellen Wijsman, PhD, Professor, Dept. of Medical Genetics. Title: From families to causal variants in the Alzheimer's Disease Sequencing Project: what have we learned from whole-genome sequencing and what are the challenges.

October 28, 2019 Dr. Olav Andersen, PhD, Dept. of Biomedicine-Medical Biochemistry, Aarhus University, Denmark. Title: The Alzheimer’s disease gene SORL1: Discovery of a novel exon implying synaptic functions besides AAP trafficking. (Summary PDF)

June 3, 2019, 4-5pm: Speaker: Pierre D. Mourad, PhD, Professor, Division of Engineering and Mathematics. Title: Towards use of transcranial, near-diagnostic ultrasound to treat dementia (Summary PDF)

December 2018 - May 2019 - no meetings

November 5, 2018: Speaker: Dr. Debby Tsuang, Professor, Dept. of Psychiatry and Behavioral Sciences, UW/ Adjunct Professor, Epidemiology/ Director, Geriatric Research, Education, and Clinical Center (GRECC), VA Puget Sound Heath Care System. Genetics of Alzheimer's Disease: a Public Health Perspective Location: Location: Rm 812, Bldg 1, VA Puget Sound, 4-5pm. 

October 1, 2018 Speaker: Dr. Elaine Peskind, Professor, Dept. of Psychiatry and Behavioral Sciences, UW. Drain the Swamp: Prazosin for Prevention of Neurodegeneration. UW Health Sciences Building RR202, 4-5pm. (Summary PDF)

September 10, 2018 4-5pm - Speaker: Shelly Erickson, PhD, Research Assist. Professor, Division of Gerontology, UW. Serum amyloid A proteins and their interactions with the blood-brain barrier in Alzheimer's disease. Location: Rm 812, Bldg 1, VA Puget Sound. (Summary PDF)

July - August 2018 - No meetings

June 4th, 2018 - Speaker: Dr. Melissa Barker-Haliski, PhD, Research Assistant Professor, UW Dept. of Pharmacy. Presenilin 2 variants age-dependently alter susceptibility to chronic seizures and anticonvulsant drug response. Location: UW Health Sciences Building RR202, 4-5pm 

May 2018 - No meeting

April 2, 2018: Speaker: Jing Zhang, M.D., Ph.D. Professor of Pathology, Shaw Endowed Chair in Neuropathology, Adjunct Professor of Neurology, Ophthalmology and Oral Health Sciences, University of Washington. - Blood-based but CNS specific biomarkers for Alzheimer's disease and Parkinson's disease. Location: Research & Training Building, Rm 109/113, 4-5pm (Summary PDF)

March 15, 2018: Speakers: Haakon Nygaard, Fipke Professor in Alzheimer’s Research, UBC / Matthew Farrer, Professor, Dept. of Medical Genetics, UBC. UWMC, RR-202, 3-4pm. (No summary available.)

December 4, 2017 4:00-5:00 pm. Turner Auditorium, D-209 Health Sciences Building - Dr. Andy Teich, MD, PhD, Assistant Professor of Pathology & Cell Biology, Columbia University/ Neuropathology Core Co-Lead, Columbia University ADRC/ Co-Director New York Brain Bank - A Systems Biology Approach to Discovering Novel Drivers of Disease in AD. (Summary PDF)

November 6, 2017 - Brenda Degerald, Senior Array and Genotyping Specialist, Illumina & Jonathan Bibliowicz, PhD, Senior Sequencing Specialist, Illumina - Genomic Solutions for the Study of Complex Neurodegenerative Disorders. A special seminar to hear about and discuss the newest technology from Illumina (Summary PDF)

October 2, 2017 - Dr. Gwenn Garden, Md, PhD, Professor, UW Department of Neurology, ADRC Affiliate Member - Microglia in AD Pathogenesis (PDF)

September 11, 2017 - Dr. Brian Kraemer, PhD, Research Associate Professor, Gerontology & Geriatric Medicine, UW, Investigator, VA Puget Sound Health Care System/  ADRC Affiliate Member - MSUT2: a novel therapeutic target for Alzheimer’s Disease (Summary PDF)

August 7th, 2017 - Elizabeth Blue, UW Division of Medical Genetics/ ADRC Affiliate Member - Variants regulating NCSTN and ZBTB4 are associated with age-at-onset of Alzheimer’s disease (Summary PDF)

July 2017 - No meeting

June 2017- No meeting

May 2017 - Ben Logsdon, Senior Scientist, Sage Bionetworks/ ADRC Affiliate Member - Transcriptomic Network Prioritization of Alzheimer’s Disease Drivers (PDF)

April 2017 - No meeting

March 2017 - Daniel Promislow, Professor, Departments of Pathology and Biology, University of Washington - Systems biology of neurodegenerative disease in the fruit fly, Drosophila melanogaster (Summary PDF)

February 2017 - No meeting

January 2017 - Matt Kaeberlein, Professor, UW Department of Pathology, ADRC Project 1 Leader - Preventing Alzheimer’s disease by targeting the hallmarks of aging (PDF)

December 2016 - Paul Crane, Professor of Medicine, UW Medicine/ ADRC Affiliate Member - Cognitive testing data to sub-group people with Alzheimer's disease (PDF)

November 2016 - Jessica Young, Assistant Professor, UW Department of Pathology/ ADRC Affiliate Member - Probing cellular mechanisms of sporadic Alzheimer’s disease risk using patient stem cells (Summary PDF)

 

For questions about this symposium, please contact Annika Noreen at annikn@uw.edu. For questions about this archive, contact Genevieve Wanucha at gwanucha@uw.edu.