AD@UW

AD@UW is a monthly 90-minute lunch-time meeting held 12:00 pm - 1:30 pm on 4th Fridays that is intended to provide a basic understanding of Alzheimer's disease and related dementias as well as research resources available through the UW ADRC.

 Find AD@UW recorded presentations on the ADRC Research Talks Video Channel

Each month, AD@UW will be focused on a different ADRD topic, and will include training, Q&A, and discussion led by UW ADRC faculty guides. Content will feature selected videos from the online Dementia for Scientists Curriculum published by the Michigan Alzheimer's Disease Center. UW Faculty guides will also outline and discuss resources available at the UW ADRC, including biological samples, imaging and clinical data, and faculty expertise.

All meetings this year will be held remotely via Zoom. Please see below for meeting links and talk recordings.

 

AD@UW Schedule

Blue highlighted presentations are recommended preparation prior to the in-person session.

 

 

January 2023

 Book discussion: Can You Help Me?: Inside the Turbulent World of Huntington Disease with   Thomas D. Bird, MD, Professor Emeritus, UW Medicine, UW Department of Neurology,   Chief, UW Division of Neurogenetics

 Friday  -  1/27/23  -  12:00-1:30 pm

  Zoom Link

 Faculty   Guides:

 Thomas   Bird,  MD

 

 

Past UW@AD Presentations

(Recordings & Curriculum Resources)

 

December 2022

  Dementia Definition and Evaluation

  Friday  -  12/2/22  -  12:00-1:30

  Zoom link

  Faculty Guides:

 Suman Jayadev, MD

 Shelly Erickson, PhD
 

  Dementia for Scientists Curriculum

  Defining Dementias, Clinical Features, Natural History (Video)
  Definition, clinical features and history of primary degenerative diseases. Required for REC trainees.

  Neuropsychology of Alzheimer's Disease and Mild Cognitive Impairment (Video)
  Clinical presentation, underlying neuropathology, and cognitive ramifications of AD and MCI. Required for REC    trainees.

  Clinical Evaluation of Dementias Part 1 (Video)
  Discusses a general approach to evaluation of patients presenting with cognitive change. Required for REC       trainees.

  Clinical Evaluation of Dementias Part 2 (Video)
  Case presentations of primary and secondary dementias.

  Behavioral & Psychiatric Features of Dementia Part 1 (Video)
  Background on general geriatric psychiatry including anxiety disorders, depression, psychosis, etc.

  Behavioral & Psychiatric Features of Dementia Part 2 (Video)

 

October 2022

  Dementia Pathology and Pathogenesis

  Friday  -  10/28/22  -  12:00-1:30

  Zoom link

 Faculty guides

 Caitlin Latimer, MD, PhD

 Christine Mac Donald, PhD

 
 
  Dementia for Scientists Curriculum
 

  Alzheimer's Disease - The amyloid cascade, alternative mechanisms (Video)
  Introduction to the role of amyloid  β in neurodegenerative diseases. Required for REC trainees.

  Alzheimer's Disease - Amyloidopathy (Video)
  Fundamental concepts of amyloidopathy. Required for REC trainees.

  Alzheimer's Disease - Tau Biology and Pathology (Video)
  In-depth discussion for scientists with genetics background who want to know more about formation and     structure of tau.

  Lewy Body Dementia - Synucleinopathies & Synuclein (Video)
  In-depth discussion of LBD and alpha-synulcein.

  Vascular Dementias (Video)
  General background of vascular dementia prevalence, epidemiology, criteria, presentation, and     comorbidity with AD.

  Pathology of Dementia, Degenerative and Spinal Cord Diseases (Video)
  Warning: graphic content. Neuropathology of different types of dementia and movement disorders.

 

April 2022

  ADRC Native Research and Resource Core

  Friday  -  April 22, 2022  -  12:00-1:30 pm

  Zoom link

 

 Faculty guides

 Dedra Buchwald, MD

 

 

 

May 2022

  Dementia Imaging

  Friday  -  May 27, 2022  -  12:00-1:30 pm

  Zoom link

  Faculty Guides:

  Thomas Grabowski, MD

  

 

 Dementia for Scientists Curriculum

 PET Imaging of Dementias (Video)

 Using brain imaging and biomarkers for diagnosis and investigation of Alzheimer's Disease (Video)

 

June 2022

  ACT - Adult Changes in Thought Study

  Friday  -  June 24, 2022  -  12:00-1:30 pm

  Zoom link

 

 Faculty guides

 Paul Crane, MD, MPH

 

 

 

February 2022

  The NIH Research Project Grant (R01)

  Friday  -  Feb. 25, 2022  -  12:00-1:30 pm

 

 

 Faculty guides

 Marie Davis, MD, PhD

 Swati Rane Levendovszky, PhD

 Astrid Suchy-Dicey, PhD

 

January 2022

  Book discussion: How Not to Study a Disease: the Story of Alzheimer’s by Dr. Karl     Kerrup,   PhD. Moderated by Jeff Iliff, PhD, Professor, UW Dept. Psychiatry & Behavioral   Sciences/UW     Neurology/UW ADRC REC Lead

 Monday  -  1/10/22  -  1:00-2:00 pm

  Zoom Link 

  Meeting ID 973 9881 4318

  Faculty   Guides:

  Jeff   Iliff, PhD

 

 
 

Book discussion: 

How Not to Study a Disease: the Story of Alzheimer’s 

Karl Herrup, PhD, Professor of Neurobiology, 

University of Pittsburgh School of Medicine

Investigator, University of Pittsburgh ADRC

This discussion directly follows  the January ADRC Seminar Series: Location, location, location: DNA in microglial cytoplasm spells trouble to be held at 12 - 1 pm at the same Zoom link as listed above.

 

  Dementia Pathology and Pathogenesis

  Friday  -  10/25/21  -  12:00-1:30

 Faculty guides

 Caitlin Latimer, MD, PhD

 
 
  Dementia for Scientists Curriculum
 

  Alzheimer's Disease - The amyloid cascade, alternative mechanisms (Video)
  Introduction to the role of amyloid  β in neurodegenerative diseases. Required for REC trainees.

  Alzheimer's Disease - Amyloidopathy (Video)
  Fundamental concepts of amyloidopathy. Required for REC trainees.

  Alzheimer's Disease - Tau Biology and Pathology (Video)
  In-depth discussion for scientists with genetics background who want to know more about formation and     structure of tau.

  Lewy Body Dementia - Synucleinopathies & Synuclein (Video)
  In-depth discussion of LBD and alpha-synulcein.

  Vascular Dementias (Video)
  General background of vascular dementia prevalence, epidemiology, criteria, presentation, and     comorbidity with AD.

  Pathology of Dementia, Degenerative and Spinal Cord Diseases (Video)
  Warning: graphic content. Neuropathology of different types of dementia and movement disorders.

 

 

  Dementia Definition and Evaluation

  Friday  -  9/24/21  -  12:00-1:30

  Zoom link

  Faculty Guides:

  Suman Jayadev, MD
 

  Dementia for Scientists Curriculum

  Defining Dementias, Clinical Features, Natural History (Video)
  Definition, clinical features and history of primary degenerative diseases. Required for REC trainees.

  Neuropsychology of Alzheimer's Disease and Mild Cognitive Impairment (Video)
  Clinical presentation, underlying neuropathology, and cognitive ramifications of AD and MCI. Required for REC    trainees.

  Clinical Evaluation of Dementias Part 1 (Video)
  Discusses a general approach to evaluation of patients presenting with cognitive change. Required for REC       trainees.

  Clinical Evaluation of Dementias Part 2 (Video)
  Case presentations of primary and secondary dementias.

  Behavioral & Psychiatric Features of Dementia Part 1 (Video)
  Background on general geriatric psychiatry including anxiety disorders, depression, psychosis, etc.

  Behavioral & Psychiatric Features of Dementia Part 2 (Video)

 

 

  Research in Ethnically Diverse Populations:

  Outreach, Recruitment, and Engagement  (ORE) Core

  Friday  -  6/25/21  -  12:00-1:30 pm

 

  Faculty Guides:

  Ka'imi  Sinclair, PhD, MPH

  Gary Ferguson 

 

  Dementia for Scientists Curriculum

  Engaging African Americans in Research: Value of a Participant Registry (Video) (required for REC       trainees)

  Improving Accuracy in the Use of Cognitive Testing with African Americans (Video)

  Cognitive and Brain Aging in Older African Americans (Video)

 

 

  ADRC DB & Biostatistical Resources

  Career Development Awards

  Friday  -  5/28/21  -  12:00-1:30 pm

 

 

  Faculty Guides:

  Ellen Wijsman, PhD

  Nicole Liachko, PhD

 Abigail Schindler, PhD

 

 

  Imaging

  Friday  -  4/23/21  -  12:00-1:30 pm

  Recording

  Meeting ID: 921 9312 6191

  Faculty Guides:

  Thomas Grabowski, MD

  Swati Rane, PhD

 

 Dementia for Scientists Curriculum

 PET Imaging of Dementias (Video)

 Using brain imaging and biomarkers for diagnosis and investigation of Alzheimer's Disease (Video)

 

 

  ACT and Psychometrics

  Friday  -  3/26/21  -  12:00-1:30 pm

 

  Faculty Guides:

  Paul Crane, MD, MPH

  Carolyn Parsey, PhD

 

 

 Therapy Development in Dementias  

  Recording Part 1 - Preclinical Considerations for Alzheimer's Disease.

  Recording Part 2 - Alzheimer's Disease Therapeutics: State of the Art

  

  Friday  -  1/22/21  -  12:00-1:30 pm

  Faculty Guides:

  Elaine Peskind, MD

  Brian Kraemer, PhD

  
 

 Dementia for Scientists Curriculum

 Alzheimer's Disease: Current & Future Drug Treatments  (Video)
 Overview and history of AD drug development. Content starts after 4 minutes of intro. Required for REC  trainees.

  Clinical Trials (Video)
  Overview and explanation of clinical trial stages. Required for REC trainees. 

  Pharmacologic Treatment of Dementias (Video)
  Summary of current medication options.

  Drug Development and FDA Review Process (Video)
 Simplified summary from bench development to post-market safety monitoring.

  Biomarkers & Biomarker Development  (Video)
  Explanation of biomarkers and their use in drug development.

  Non-Pharmacologic Interventions  (Video)
  Introduction to non-pharmacologic interventions in AD.

 

 Dementia Genetics 

  Recording

  Companion story: The Early ADRC’s Search for an Alzheimer’s Gene

  Friday  -  12/11/20  -  12:00-1:30

  Faculty Guides:

  Thomas Bird, MD

  Jessica Young, PhD

  
 

 Dementia for Scientists Curriculum

 Genetics of Alzheimer's Disease  (Video)
  Introduction to the genetics of AD. Required for REC trainees. 

  Genetic Risks and Genetics in Clinical Practice  (Video)
  Detailed assessment of APOE and genetic testing in AD. Required for REC trainees. 

  Genetics and Pathogenesis of Amyotrophic Lateral Sclerosis & Frontotemporal Dementia (Video)
  Comprehensive discussion of similarities and differences between ALS and FTD. 

  Ethical Issues in Neurogenetic Conditions  (Video)
  Practical approaches to genetic testing. 

 

  Dementia Definition and Evaluation

  Friday  -  10/23/20  -  12:00-1:30

  ADRC Clinical Core Resources

  Faculty Guides:

  Suman Jayadev, MD

  Kimiko Domoto-Reilly, MD

  Kelly Green, PA-C
 

  Dementia for Scientists Curriculum

  Defining Dementias, Clinical Features, Natural History (Video)
  Definition, clinical features and history of primary degenerative diseases. Required for REC trainees.

  Neuropsychology of Alzheimer's Disease and Mild Cognitive Impairment (Video)
  Clinical presentation, underlying neuropathology, and cognitive ramifications of AD and MCI. Required for REC    trainees.

  Clinical Evaluation of Dementias Part 1 (Video)
  Discusses a general approach to evaluation of patients presenting with cognitive change. Required for REC       trainees.

  Clinical Evaluation of Dementias Part 2 (Video)
  Case presentations of primary and secondary dementias.

  Behavioral & Psychiatric Features of Dementia Part 1 (Video)
  Background on general geriatric psychiatry including anxiety disorders, depression, psychosis, etc.

  Behavioral & Psychiatric Features of Dementia Part 2 (Video)

 

  Dementia Pathology and Pathogenesis

  Friday  -  9/25/20  -  12:00-1:30

  Recording 

 Faculty guides

 C. Dirk Keene, MD, PhD

 Caitlin Latimer, MD, PhD

 
 
  Dementia for Scientists Curriculum
 

  Alzheimer's Disease - The amyloid cascade, alternative mechanisms (Video)
  Introduction to the role of amyloid  β in neurodegenerative diseases. Required for REC trainees.

  Alzheimer's Disease - Amyloidopathy (Video)
  Fundamental concepts of amyloidopathy. Required for REC trainees.

  Alzheimer's Disease - Tau Biology and Pathology (Video)
  In-depth discussion for scientists with genetics background who want to know more about formation and     structure of tau.

  Lewy Body Dementia - Synucleinopathies & Synuclein (Video)
  In-depth discussion of LBD and alpha-synulcein.

  Vascular Dementias (Video)
  General background of vascular dementia prevalence, epidemiology, criteria, presentation, and     comorbidity with AD.

  Pathology of Dementia, Degenerative and Spinal Cord Diseases (Video)
  Warning: graphic content. Neuropathology of different types of dementia and movement disorders.