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ADRC Project 2
Identification of Age of Onset Genes
Gerard Schellenberg, Ph.D., Principal Investigator

The goal of this project is to identify genes that modify age of onset of AD. Aims are to identify chromosomal regions containing genes that modify age-of-onset of PSEN2 mutation carriers (Volga German kindreds with the N141I mutation); identify chromosomal regions containing genes modifying age-of-onset in (PSEN1) mutation carriers; and characterize the relationship between APOE haplotypes and familial AD in the presence of other covariates.

UW ADRC Director--Murray Raskind, M.D.
UW ADRC Education and Training Director--James Leverenz, M.D.
Last Modified: Friday, 09-Jan-2009 13:31:35 PST