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ADRC Project 2
Identification of Age of Onset Genes
Gerard Schellenberg, Ph.D., Principal Investigator
zachdad@u.washington.edu

The goal of this project is to identify genes that modify age of onset of AD. Aims are to identify chromosomal regions containing genes that modify age-of-onset of PSEN2 mutation carriers (Volga German kindreds with the N141I mutation); identify chromosomal regions containing genes modifying age-of-onset in (PSEN1) mutation carriers; and characterize the relationship between APOE haplotypes and familial AD in the presence of other covariates.


adrcweb@u.washington.edu
UW ADRC Director--Murray Raskind, M.D.
UW ADRC Education and Training Director--James Leverenz, M.D.
Last Modified: Friday, 09-Jan-2009 13:31:35 PST