Initial Analyses Available from the Aging, Dementia, and Traumatic Brain Injury (TBI) Study
November 10, 2017 — In eLife, UW ADRC and Allen Brain researchers present an open-access resource of detailed molecular characterization of 107 brains from UW ACT Study. They detail the initial analyses to understand features of the aged brain, the relationship of dementia and pathology, and transcriptional signatures of dementia, neuropathology, and aging.
New In JAMA - Advance Directives for Dementia: Meeting a Unique Challenge
November 07, 2017 — Publishing Nov 6 in JAMA, UW Memory Brain's Drs. Gaster, Larson (ADRC), and Curtis lay out vision of better advance directives for dementia patients. They see a way to better align the medical care that patients get with the care they would have wanted, prevent suffering, and help families honor loved ones' wishes for life sustaining treatments.
20-Year Follow-Up to ACTIVE Study Gets Funded
October 26, 2017 — Co-PIs, Sherry Willis, PhD and (UW Medicine) George Rebok, PhD, (Johns Hopkins) were awarded $756k from NIH for a 20-year follow-up to the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) study.
ADRC Assoc. Director Dr. Eric Larson published a book on aging for the public!
October 25, 2017 — "I knew I needed to write a book to try to tell an accurate story of aging." Read this UW SPH interview with ADRC's Dr. Eric Larson on his new book 'Enlightened Aging.'
Revised, Expanded NACC FY2018 Funding Opportunity Announcement: New Investigator Awards
October 20, 2017 — The New Investigator Awards will be funded at a level of $135,000 each (total costs) and no longer require focus solely on the secondary analysis of NACC data, plus other new highlights. Read more.
WATCH: Updated Diagnostic Criteria and Management of Lewy Body Dementia, DLB Consortium
October 16, 2017 — The new criteria elevate the importance of REM sleep disorder and incorporate the biomarker MIBG. DLB Consortium leaders hope that the diagnostic and management guidelines help clinicians catch more DLB cases. This resource will make this cognition and movement disorder more tractable for biomarker research, longitudinal cohorts, and clinical trials. Have you adopted the guidelines? What’s working, what’s not? How are they informing your research? View here.
NIH completes atlas of human DNA differences that influence gene expression
October 11, 2017 — This atlas is a critical resource for the scientific community interested in how individual genomic variation leads to biological differences, like healthy and diseased states, across human tissues and cell types. The culmination of work from the Genotype-Tissue Expression (GTEx) Consortium, the atlas catalogs how genomic variation influences how genes are turned off and on.
ITHS now accepting applications for three ITHS career development programs
October 11, 2017 — ITHS Education Program supports investigators, graduate students, and scholars, through training opportunities and mentored career development. Applications have just opened for all three structured education programs. Applications are due October 30, 2017.
LBD University: Updated Diagnostic Criteria and Management of Lewy Body Dementia
October 06, 2017 — The Dementia with Lewy Bodies (DLB) Consortium (including ADRC's Debby Tsuang) published updated diagnostic criteria for dementia with Lewy bodies in the journal Neurology. This 10/10 webinar will highlight the key changes for healthcare professionals to better diagnosis and manage their DLB patients. Register here!
New Paper: Translational geroscience: A new paradigm for 21st century medicine
October 05, 2017 — Published in Translational Medicine of Aging, ADRC's Dr. Matt Kaeberlein provides an overview of the field of translational geroscience, which he believes will become the paradigm for the practice of medicine in the 21st century. He cites initial clinical data indicates that geroprotective compounds such as rapamycin and metformin may delay or reverse age-related disease in otherwise healthy elderly people.