researchers affiliated with the University of Washington Alzheimer's Disease Center; insulin; healthy aging; pathology of Alzheimer's disease

UW ADRC Researchers                                                            

Faculty Researchers

Bird_Headshot.jpgThomas D. Bird, MD

Professor, Department of Neurology & Medical Genetics, University of Washington

Research Interests: Genetics of Alzheimer's disease; identifying genes associated with familial neurodegenerative disorders and other hereditary neurologic disorders; phenotype/genotype correlations; isolating chromosomal locations related to particular disorders

Publications

Keene_Headshot.jpgChristopher (Dirk) Keene, MD, PhD

Assistant Professor, Department of Pathology, University of Washington

Research Interests: The innate immune response in the brain and retina; identification of key genes and pathways involved in neurotoxicity derived from chronic innate immune activation in diseases such as Alzheimer's disease, Parkinson's disease, and glaucoma

Publications

Jim-Leverenz.jpgJames Leverenz, MD

Professor, Departments of Neurology and Psychiatry & Behavioral Sciences, University of Washington

Research Interests: Clinical and neuropathologic aspects of aging-associated disorders including Alzheiemer's disease, Parkinson's disease, Dementia with Lewy bodies, frontotemporal dementia, Down syndrome

Publications

Gail-Li.jpgGail Li, MD, PhD

Associate Professor, Department of Psychiatry & Behavioral Sciences, University of Washington

Research Interests: CSF biomarkers for Alzheimer's disease; Vascular risk and protective factors for Alzheimer's disease in a community-based populations; The potential protective effects of simvastatin for Alzheimer's disease in normal control subjects

Current CV

Montine_Headshot.jpgThomas Montine, PhD

Professor and Acting Chair, Department of Pathology, University of Washington

Research Interests: The structural and molecular bases of cognitive impairment in Alzheimer’s and Parkinson’s diseases; Defining key pathogenic steps and thereby identify new potential therapeutic targets through a combination of epidemiology-related neuropathology, biomarkers for clinical trials, and experimental studies

PublicationsLab Link

Elaine-Peskind.jpgElaine Peskind, MD

Friends of Alzheimer's Research Professor, Department of Psychiatry and Behavioral Sciences, University of Washington

Research Interests: Stress hormones in aging and Alzheimer’s disease; Cerebrospinal fluid (CSF) biomarkers of aging and neurodegenerative dementing disorders; Treatments for both the cognitive impairment and noncognitive behavioral problems of Alzheimer’s disease; Use of prazosin for combat trauma posttraumatic stress disorder (PTSD); Clinical phenomenology and neuroimaging and CSF biomarkers of neurodegeneration in combat blast concussion mild traumatic brain injury

Publications

Murray-Raskind.jpgMurray Raskind, MD

Professor and Vice-Chairman, Department of Psychiatry & Behavioral Sciences, University of Washington

Research Interests: Alzheimer's disease, aging, noncognitive behavioral problems in dementia, and PTSD in combat veterans and civilians; The use of prazosin for the treatment of combat-related trauma nightmares and sleep disturbances

Publications

Skinner_Headshot.jpgJeannine Skinner, PhD

Senior Fellow, School of Medicine, Department of Psychiatry & Behavioral Sciences, University of Washington

Research Interests: the effects of aerobic and resistance exercise on insulin sensitivity, cognition, and biomarkers of type 2 diabetes and Alzheimer's disease in older African Americans

PublicationsUW & VA Memory Wellness Program

 

Sonen_Headshot.jpgJoshua Sonnen, PhD

Assistant Professor, Department of Pathology, University of Washington

Research Interests: Neuropathology, brain autopsy and pathology of muscles, nerves and eyes; changes in the human brain as it ages and the impact of these changes on cognitive function; mid-to-late lifestyle factors and common medications which might prevent age-related brain injury

Publications

Debby-Tsuang.jpgDebby Tsuang, MD

Professor, Department of Psychiatry & Behavioral Sciences, University of Washington

Research Interests: Clinical-neuropathology of dementing disorders; psychosis in dementia genetics; endophenotypes of schizophrenia

Publications

Wang_Headshot.jpgLucy Wang, MD

Acting Assistant Professor, Department of Psychiatry & Behavioral Sciences, University of Washington

Research Interests: The use prazosin to reduce disruptive behaviors and agitation in Alzheimer's; the role of hormones and the nervous system in agitation and dementia

Publications

Wjisman_Headshot.jpgEllen Wijsman, PhD

Professor, Department of Medicine and Biostatistics, Division of Medical Genetics

Research Interests: The development and application of quantitative methods for analysis of human genetic data, including statistical techniques of gene mapping, modelling modes of inheritance, and identifying regions of identity-by-descent

Publications

Chang-Ed_Headshot.jpgChang-En Yu, PhD

Research Associate Professor, Division of Genrontology & Geriatric Medicine, University of Washington

Research Interests: Molecular genetics of neurodegenerative and psychiatric disorders, which include Alzheimer’s disease (AD), frontotemporal dementia (FTD), schizophrenia, and autism

Publications

Affiliated Researchers

Eric-Petrie.jpgEric Petrie, MD

Associate Professor, Department of Psychiatry & Behavioral Sciences, University of Washington

Research Interests: The development of Positron Emission Tomography (PET) radiotracers to better characterize the neurobiology giving rise to psychiatric symptoms in patients with Alzheimer's Disease and Posttraumatic Stress Disorder (PTSD); Characterizing potential neuroimaging biomarkers of mild traumatic brain injury in blast-exposed military personnel and in civilian athletes

Publications

Wilkinson_Headshot.jpgCharles Wilkinson, PhD

Research Associate Professor, Department of Psychiatry & Behavioral Sciences, University of Washington

Research Interests: Pituitary gland damage as a result of concussion (mild traumatic brain injury), which may lead to chronic fatigue, depression, sleep disturbance, cognitive deficiencies, sexual dysfunction, increased cardiovascular morbidity, and diminished quality of life

Publications

Cyrus_Headshot.jpgCyrus P. Zabetian, PhD

Associate Professor, Department of Neurology, Division of Neurogenetics, University of Washington

Research Interests: Identification of genes that alter risk or modify clinical characteristics in neurodegenerative diseases, particularly Parkinson's disease; developing intermediate phenotypes in complex neurological diseases; genotype phenotype correlation in genes related to noradrenergic signaling

Publications