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Elaine R. Peskind, M.D.

Position: Professor

Qualifications:

• B.S., California State College, San Bernadino, CA, Biology, 1975
• M.S., Washington State University, Pullman, WA, Zoology, 1978
• M.D., University of Washington School of Medicine, Seattle, WA, Medicine, 1986

Past Positions:

• 2002-present, Associate Director, UW Alzheimer's Disease Research Center
• 2000-present, Professor, Department of Psychiatry and Behavioral Sciences, UW School of Medicine
• 1997-present, Associate Director, Mental Illness Research, Education and Clinical Center (MIRECC), Northwest Network
• 1996-2000, Associate Professor, Department of Psychiatry and Behavioral Sciences, UW School of Medicine
• 1995-present, Director of Clinical Research for Mental Health Service, VAPSHCS
• 1994-1997, Staff Psychiatrist, VA Puget Sound Health Care System (VAPSHCS)
• 1991-1996, University of Washington School of Medicine, Dept. of Psychiatry and Behavioral Sciences, Assistant Professor
• 1991-1994, University of Washington Medical Center, Attending Psychiatrist

Honors and Awards:

• 1997-2001 National Institute on Aging Neuroscience of Aging Review Committee
• 1996 Elected Member, American College of Neuropsychopharmacology
• 1990 American College of Neuropsychopharmacology-Mead Johnson Travel Award
• 1990 Director's Award, Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine
• 1990 Sandoz Research Award
• 7/90-6/91 Thomas H. Holmes Research Scholar Award
• 7/89-6/91 Research Training for Veterans Administration Psychiatrists Award
• 1986 Janet M. Glasgow Memorial Achievement Citation of the American Medical Women's Assoc.
• 1986 Margaret H. O'Donnell Prize in Psychiatry, University of Washington School of Medicine
• 1986 Graduation with Honors, University of Washington School of Medicine
• 1985 Rock Sleyster Scholar, American Medical Association
• 1985 Alpha Omega Alpha, elected Junior year
• 1984 Herbert S. Ripley Psychiatry Research Thesis Award, University of Washington School of Medicine
• 1975 Graduation with High Honors, California State College, San Bernadino
• 1973 California Heart Association Student Research Associateship
• 1971 Riverside Foundation Scholarship

Selected Publications:

• Watson GS, Peskind ER, Asthana S, Purganan K, Wait C, Chapman D, Schwartz MW, Plymate S, Craft S. Insulin increases CSF Abeta42 levels in normal older adults. Neurology 60:1899-1903, 2003.
• Wolkowitz OM, Kramer JH, Reus VI, Costa MM, Yaffe K, Walton P, Raskind M, Peskind E, Newhouse P, Sack D, DeSouza E, Sadowsky C, Roberts E, DHEA Alzheimer's Disease Collaborative Research. DHEA treatment of Alzheimer's disease: a randomized, double-blind, placebo-controlled study. Neurology 60:1071-1076, 2003.
• Aisen PS, Berg JD, Craft S, Peskind ER, Sano M, Teri L, Mulnard RA, Thomas RG, Thal L. Steroid-induced elevation of glucose in Alzheimer's disease: relationship to gender, apolipoprotein E genotype and cognition. Psychoneuroendocrinology 28:113-120, 2003.
• Bonner LT, Peskind ER. Pharmacologic treatments of dementia. Med Clin North Am 86:657-674, 2002.
• Leverenz JB, Agustin CM, Tsuang D, Peskind ER, Edland SD, Nochlin D, DiGiacomo L, Bowen JD, McCormick WC, Teri L, Raskind MA, Kukull WA, Larson EB. Clinical and neuropathological characteristics of hippocampal sclerosis: a community-based study. Arch Neurol 59:1099-1106, 2002.
• Rosin RA, Levine MD, Peskind E. Transdermal nicotine for agitation in dementia. Am J Geriatr Psychiatry 9:443-444, 2001.
• Peskind ER, Griffin WS, Akama KT, Raskind MA, Van Eldik LJ. Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's disease. Neurochem Int 39:409-413, 2001.
• Peskind ER, Wilkinson CW, Petrie E, Schellenberg G, Raskind MA. Increased CSF cortisol in Alzheimer's disease is a function of apolipoprotein E genotype. Neurology 56:1094-1098, 2001.
• Leverenz JB, Dobie DJ, Miller M, Peskind ER, Raskind MA. Alpha-2 adrenergic receptor upregulation in Lewy body variant of Alzheimer's disease. Neurobiol Aging 22:555-561, 2001.
• Teri L, Logsdon RG, Peskind E, Raskind M, Weiner MF, Tractenberg RE, Foster NL, Schneider LS, Sano M, Whitehouse P, Tariot P, Mellow AM, Auchus AP, Grundman M, Thomas RG, Schafer K, Thal LJ. Treatment of agitation in Alzheimer's disease patients: a randomized placebo controlled clinical trial. Neurology 55:1271-1278, 2000.
• Raskind MA, Peskind ER, Holmes C, Goldstein D. Patterns of cerebrospinal fluid catechols support increased central noradrenergic responsiveness in aging and Alzheimer's disease. Biol Psychiatry 46:756-765, 1999.
• Tsuang D, Larson EB, Bowen J, McCormick W, Teri L, Nochlin D, Leverenz JB, Peskind ER, Lim A, Raskind MA, Thompson ML, Mirra S, Gearing M, Schellenberg G, Kukull W. The utility of apolipoprotein E genotyping in the diagnosis of Alzheimer's disease in a community-based case series. Arch Neurol 56:1489-1495, 1999.
• Craft S, Peskind E, Schwartz MW, Schellenberg GD, Raskind M, Porte D Jr. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology 50:164-168, 1998.
• Peskind ER, Elrod R, Dobie DJ, Pascualy M, Petrie E, Jensen C, Brodkin K, Murray S, Veith RC, Raskind MR. Cerebrospinal fluid epinephrine in Alzheimer's disease and normal aging. Neuropsychopharmacology 19:465-471, 1998.
• Raskind MA, Peskind ER. Treatment of noncognitive symptoms in Alzheimer's disease and other dementia. In: American Psychiatric Press Textbook of Psychopharmacology (2nd ed.), AF Schatzberg, CB Nemeroff (eds.). Washington DC, American Psychiatric Press, pp. 791-801, 1998.
• Tsuang D, Leverenz J, Peskind E, Bird T, Schellenberg G, Sumi M, Raskind MA. The effect of apolipoprotein E genotype on expression of an autosomal dominant schizophreniform disorder with progressive dementia and neurofibrillary tangles. Biol Psychiatry 41:191-195, 1997.
• Wilkinson CW, Peskind ER, Raskind MA. Decreased sensitivity to glucocorticoid negative feedback in human aging. Neuroendocrinology 65:79-90, 1997.
• Peskind ER, Leverenz J, Farlow MR, Ito RK, Provow SA, Siegel RS, Cleveland M, Morgan CH, Pandian MR, Nochlin D, Schellenberg GD, Wagner SL. Clinicopathologic correlations of soluble amyloid beta-protein precursor in cerebrospinal fluid in Alzheimer's disease patients and controls. Alz Dis Assoc Disorders 11:201-216, 1997.
• Elrod R, Peskind ER, DiGiacomo L, Brodkin K, Veith RC, Raskind MA. Effects of Alzheimer's disease severity on cerebrospinal fluid norepinephrine. Am J Psychiatry 154:25-30, 1997.
• Peskind ER, Raskind MA. Cognitive Disorders. In: Textbook of Geriatric Psychiatry. EW Busse, DG Blazer (Eds). Washington, D.C., American Psychiatric Press, pp. 213-234, 1996.
• Tsuang D, Kukull W, Sheppard L, Barnhart R, Peskind E, Edland S, Schellenberg G, Larson E, Raskind MA. Impact of sample selection on APOE-e4 allele frequency: a comparison of two Alzheimer's disease samples. JAGS 44:704-707, 1996.
• Peskind ER, Raskind MA, Wingerson D, Pascualy M, Thal L, Dobie DJ, Wilkinson CW. Hypothalamic-pituitary-adrenocortical axis responses to physostigmine: effects of Alzheimer's disease and gender. Biol Psychiatry 40:61-68, 1996.
• Schwartz MW, Peskind ER, Raskind MA, Nicolson M, Moore J, Morawiecki A, Boyko E, Porte D Jr. Cerebrospinal fluid leptin levels: relationship to plasma levels and body adiposity in humans. Nature Medicine 2:589:592, 1996.
• Peskind ER, Raskind MA, Wingerson D, Pascualy M, Thal L, Dobie DJ, Wilkinson CW. Hypothalamic-pituitary-adrenocortical axis responses to physostigmine: effects of Alzheimer's disease and gender. Biol Psychiatry 40:61-68, 1996.
• Peskind ER, Pascualy M, Edland SD, Wingerson D, Dobie DJ, Raskind MA. Plasma arginine vasopressin response to hypertonic saline infusion in Alzheimer's disease. Alz Dis Assoc Dis 9:238-242, 1995.
• Raskind MA, Peskind ER, Pascualy M, Dobie DJ, Murray S, Sikkema C, Veith RC, Dorsa DM, Wilkinson CW. The effects of normal aging on cortisol and adrenocorticotropin responses to hypertonic saline solution. Psychoneuroendocrinology 20:637-644, 1995.
• Peskind ER, Wingerson D, Pascualy M, Thal L, Veith RC, Dorsa DM, Bodenheimer S, Raskind MA. Oral physostigmine in Alzheimer's disease: effects on norepinephrine and vasopressin in cerebrospinal fluid and plasma. Biol Psychiatry 38:532-538, 1995.
• Peskind ER, Wingerson D, Murray S, Pascualy M, Dobie DJ, LeCorre P, LeVerge R, Veith RC, Raskind MA. Effects of Alzheimer's disease and normal aging on cerebrospinal fluid norepinephrine responses to yohimbine and clonidine. Arch Gen Psychiatry 52:774-782, 1995.
• Peskind ER, Raskind MA, Wingerson D, Pascualy M, Thal LJ, Dobie DJ, Veith RC, Dorsa DM, Murray S, Sikkema C, Galt SA, Wilkinson CW. Enhanced hypothalamic pituitary adrenocortical axis responses to physostigmine in normal aging. J Gerontol 50A:M114-M120, 1995.