Chiu, Vaughan receive NIH Transformative Research Award

Assistant Professor Joshua Vaughan and Professor Daniel Chiu are among the eight awardees selected by the National Institutes of Health (NIH) for a 2017 NIH Director’s Transformative Research Award. This program is one of four in the NIH High-Risk, High-Reward Research program, which funded 86 awards to scientists working in biomedical research in 2017.

The NIH High-Risk, High-Reward Research program funds exceptionally creative scientists proposing to use highly innovative approaches to tackle major challenges in biomedical research. The program accelerates scientific discovery by supporting high-risk ideas with high-impact potential, and applicants are encouraged to think outside the box and to pursue exciting, trailblazing ideas in any area of research relevant to the NIH mission.

The NIH Director’s Transformative Research Award, established in 2009, promotes cross-cutting, interdisciplinary approaches and is open to individuals and teams of investigators who propose research that could potentially create or challenge existing paradigms.

Professors Chiu and Vaughan are developing radical new technologies for high-resolution mapping of brain tissue, including circuit-level spatial information down to a resolution of 50 nanometers and comprehensive analysis of the types of proteins present across large regions of the brain. These techniques are needed because it is technically difficult to directly detect large numbers of proteins in brain tissue.

Instead of trying to measure proteins directly, most approaches measure RNA molecules—a precursor to proteins. But RNA detection in spatially complex brain tissue has its flaws. Current approaches struggle with dim signals that are difficult to detect over background noise in complex, thick tissues. Professors Chiu and Vaughan will develop new fluorescent probes to light up RNA molecules in tissues and will use a novel, large-area light sheet microscope—together with sample processing techniques—to rapidly probe large volumes of brain tissue at high spatial resolution.

The work of 2017 NIH award recipients will be featured at the 2018 High-Risk, High-Reward Research Symposium, held June 6-8, 2018 in Bethesda, MD. The symposium is free, open to the public, and will bring together recipients of the NIH Director’s Pioneer, New Innovator, Transformative Research, and Early Independence awards to share their groundbreaking research and discoveries.

To learn more about Professor Chiu and his research, please visit his faculty page and research group website.

To learn more about Professor Vaughan and his research, please visit his faculty page and research group website.

Adapted by Diana Knight from a October 6, 2017 story by Jennifer Langston of UW News and Leila Gray of UW Health Sciences/UW Medicine.

Four Faculty Members Elected Fellows of AAAS

In November 2011, the Council of the American Association for the Advancement of  Sciences (AAAS) elected 539 members as Fellows of the AAAS. These individuals will be recognized for their contributions to science and technology at the Fellows Forum to be held on 18 February 2012 during the AAAS Annual Meeting in Vancouver, British Columbia. Four faculty members from the UW Department of Chemistry were elected:

Daniel Chiu, A. Bruce Montgomery Professor of Chemistry and Endowed Professor in Analytical Chemistry

Daniel Gamelin, Harry and Catherine Jaynne Boand Endowed Professor of Chemistry

Karen Goldberg, Nicole A. Boand Endowed Professor in Chemistry

Bruce Robinson, Professor of Chemistry

See the full list of 2011 AAAS Fellows.

Daniel Chiu honored as one of UW’s most entrepreneurial faculty

Daniel Chiu, A. Bruce Montgomery Professor of Chemistry, is one of eight UW professors honored as the University’s most entrepreneurial faculty researchers, under a new Entrepreneurial Faculty Fellows Program initiated by Interim President Phyllis Wise.

The honorees have achieved success in translating their research into products and therapies or started groundbreaking programs for translation or collaboration with industry.

Fellows will mentor colleagues with entrepreneurial aspirations, advise the center on its programs and provide input on UW policies and programs related to entrepreneurship. A committee of deans and center leadership selected the inaugural awardees.

To learn more about Professor Daniel Chiu, visit his faculty page and his research group site.

Two New Professorships; Two New Holders

We are pleased to announce the establishment of two new professorships within the Department of Chemistry and the appointments of the first holders to these new positions. A generous gift from Professor Larry Dalton, in honor of his spouse, has established the Nicole A. Boand Professorship in Chemistry. Professor Karen Goldberg is the first Nicole A. Boand Professor of Chemistry. A generous gift from Bruce Montgomery, an alumnus of our undergraduate program and biotechnology pioneer, has established the A. Bruce Montgomery Endowed Professorship in Chemistry. Professor Daniel Chiu has been selected as the first Montgomery Professor of Chemistry. We thank the donors for their extraordinary contributions to our program and congratulate the new faculty appointees!

To read more about Professor Karen Goldberg, visit her faculty website. To learn more about Professor Daniel Chiu, visit his faculty page.

Click to read additional Department of Chemistry news stories about Professor Larry Dalton and Dr. Bruce Montgomery.

Professor Daniel Chiu wins Young Innovator Award in Microfluidics

Dr. Daniel Chiu, Professor of Chemistry, is the recipient of the Analytical Chemistry 2010 Young Innovator Award. This award, sponsored by Analytical Chemistry and the Chemical and Biological Microsystems Society (CBMS), recognizes the contributions of an individual who has demonstrated exceptional technical advancement and innovation in the field of micro- or nanofluidics in his or her early career.

With articles published in ACS journals such as Analytical Chemistry, Accounts of Chemical Research, Langmuir, Journal of American Chemical Society, and Nano Letters, Dr. Chiu has pioneered the development and application of new methodologies in the area of microfluidics and single-molecule manipulation and detection. Dr. Chiu has been at the forefront of advancing microfluidic techniques, ranging from methods of microfabrication, to the investigation of unique fluidic behaviors encountered in microfluidics, to the application of microfluidics to biomedical and clinical studies. He is the recipient of various awards including Alfred P. Sloan Fellow, McKnight Technological Innovations in Neuroscience Award, and Keck Distinguished Young Scholar in Biomedical Research.

Dr. Chiu will accept his award at the upcoming MicroTAS 2010 Conference in Groningen, The Netherlands from October 3 – 7, 2010.

To view the latest research published in ACS journals by Dr. Daniel Chiu, visit the Analytical Chemistry 2010 Young Innovator Award page.

Daniel Chiu receives Life Sciences Discovery Fund Grant

Professor Daniel Chiu received a 2007 Life Sciences Discovery Fund Grant. The Life Sciences Discovery Fund was established in 2005 to support “innovative research in Washington State to promote life sciences competitiveness, enhance economic vitality, and improve health and health care.”

Chiu was one of six to receive the first-ever grants awarded by the LSDF. His $760,000 grant will be used to continue his project, “monitoring breast cancer metastasis and treatment efficacy.” Breast cancer is the most frequently diagnosed cancer and the second leading cause of cancer death in Washington. The research in this study is aimed at monitoring circulating tumor cells and tumor DNA in patient blood using a chip-based device, with the goal of developing a low-cost method for monitoring breast cancer prognosis, treatment efficacy, and early diagnosis.

For more information about Daniel Chiu and his research, please visit his faculty page or his research group website.

Daniel Chiu receives National Fresenius Award

Professor Daniel Chiu received the 2007 National Fresenius Award from the Phi Lambda Upsilon Honorary Chemical Society. This annual award was established in 1965 to promote “high scholarship and original investigation in all branches of pure and applied chemistry.” The award recognizes outstanding chemists early in their professional careers, who have attained national recognition in the areas of research, teaching and/or administration.

For more information about the National Fresenius Award, please visit the PLU Fresenius website.

For more information about Daniel Chiu and his research, please visit his faculty page or his research group website.

Daniel Chiu receives Sloan Research Fellowship

Assistant Professor Daniel Chiu was one of four UW faculty members awarded a highly competitive and prestigious Sloan Research Fellowship from the Alfred P. Sloan Foundation. Sloan Research Fellowships are granted to enhance the careers of the top young academics in the sciences, and they carry a $40,000 grant over a two-year period. Currently there are 116 fellowships awarded annually across seven fields: chemistry, computational and evolutionary molecular biology, computer science, economics, mathematics, neuroscience, and physics.

Original article by Bob Roseth from the University Week publication.

For more information about the Sloan Fellowship and recent recipients, please see the Fellowship website.

For more information about Daniel Chiu and his research, please visit his faculty page or his research group website.